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Veterinary information to support practice, based on evidence and continuing education

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Abstract

WNT-β-Catenin-TCF pathway is involved in carcinogenesis and foetal development. As a member of the WNT gene family, Wnt8A encodes secreted signalling proteins and responds to many biological processes. However, similar research on the effects of genetic variations of Wnt8A gene on growth traits is...

Author(s)
Huang YongZhen; Zou Yong; Lin Qing; He Hua; Zheng Li; Zhang ZiJing; Dang YongLong; Lei ChuZhao; Lan XianYong; Qi XingShan; Chen Hong
Publisher
Indian Academy of Sciences, Bangalore, India
Citation
Journal of Genetics, 2017, 96, 4, pp 535-544
Abstract

Muscle growth is a complex phenomenon regulated by many factors, whereby net growth results from the combined action of synthesis and turnover. Insulin-like growth factor 2 (IGF2) is a fetal growth and differentiation factor that plays an important role in muscle growth and in myoblast...

Author(s)
Huang YongZhen; Zhan ZhaoYang; Sun YuJia; Wang Jing; Li MingXun; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 6, pp 327-334
Abstract

The myostatin (GDF-8) acts as a negative regulator of muscle growth. Mutations of the gene are responsible for the double muscling phenotype in several European cattle breeds. The study was conducted to determine the polymorphisms of the bovine myostatin gene at promoter region in Nanyang cattle...

Author(s)
Zhang RunFeng; Chen Hong; Zhang ZhengFeng; Zhang HaiJun; Yan LinJun; Bao Bin
Publisher
Asian Network for Biotechnology in Animal Production and Health, Haidian, China
Citation
Animal Biotechnology Bulletin, 2006, 10, 1, pp 360-362
Abstract

PCR-SSCP and DNA sequencing methods were employed to screen the genetic variation of VEGF gene in 671 individuals belonging to three Chinese indigenous cattle breeds including Nanyang, Jiaxian Red and Qinchuan. Three haplotypes (A, B and C), four observed genotypes (AA, AB, BB and AC) and three new ...

Author(s)
Pang YongHong; Wang JuQiang; Zhang ChunLei; Lei ChuZhao; Lan XianYong; Yue WangPing; Gu ChuanWen; Chen DanXia; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2011, 38, 2, pp 755-759
Abstract

Hepatocyte nuclear factor-4α (HNF-4α), a member of the hepatocyte nuclear factor family, plays an important role in regulating the expression of genes involved in the development, differentiation and normal function of liver and pancreatic β cells, as well as the maintenance of glucose homeostasis. ...

Author(s)
Wang ZiNian; Li MiJie; Lan XianYong; Li MingXun; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 546, 2, pp 206-213
Abstract

The F-box protein 32 (FBXO32), also known as Atrogin-1, is one of the four subunits of the ubiquitin protein ligase complex. FBXO32 has been previously shown to be involved in regulation of initiation and development of muscle mass. In the present study, we investigated the polymorphism of FBXO32...

Author(s)
Wang AiLan; Zhang Ya; Li MiJie; Lan XianYong; Wang JuQiang; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 515, 1, pp 181-186
Abstract

The peroxisome proliferator-activated receptor gamma coactivator-1 alpha protein, encoded by the PPARGC1A gene, is a metabolic switch, which transcriptionally activates a complex pathway of mitochondrial biogenesis, lipid and glucose metabolism. Three SNPs (exon 3 c.396G>A, intron 9 c.1892+19C>T...

Author(s)
Li MiJie; Liu Mei; Liu Dong; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 1, pp 39-44
Abstract

Paired box 3 (PAX3) belongs to the PAX superfamily of transcription factors and plays essential roles in the embryogenesis and postnatal formation of limb musculature through affecting the survival of muscle progenitor cells. By genetic mapping, PAX3 gene is assigned in the interval of quantitative ...

Author(s)
Xu Yao; Cai HanFang; Zhou Yang; Shi Tao; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Jia YuTang; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 7, pp 4295-4303
Abstract

Forkhead box A2 (Foxa2) has been recognized as one of the most potent transcriptional activators that is implicated in the control of feeding behavior and energy homeostasis. However, similar research about the effects of genetic variations of Foxa2 gene on growth traits are lacking. Therefore,...

Author(s)
Liu Mei; Li MiJie; Wang ShaoQiang; Xu Yao; Lan XianYong; Li ZhuanJian; Lei ChuZhao; Yang DongYing; Jia YuTang; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 536, 2, pp 385-392
Abstract

The aim of this study was to examine the association of the SREBP-1c polymorphism with growth traits in cattle breeds. Five sequence variants (SVs) were identified within the bovine sterol regulatory element-binding protein-1c gene (SREBP-1c), using DNA sequencing, PCR, PCR-RFLP, and forced...

Author(s)
Huang YongZhen; He Hua; Sun JiaJie; Wang Jing; Li ZhuanJian; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Zhang EnPing; Wang JuQiang; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2011, 54, 6, pp 507-516

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