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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

WNT-β-Catenin-TCF pathway is involved in carcinogenesis and foetal development. As a member of the WNT gene family, Wnt8A encodes secreted signalling proteins and responds to many biological processes. However, similar research on the effects of genetic variations of Wnt8A gene on growth traits is...

Author(s)
Huang YongZhen; Zou Yong; Lin Qing; He Hua; Zheng Li; Zhang ZiJing; Dang YongLong; Lei ChuZhao; Lan XianYong; Qi XingShan; Chen Hong
Publisher
Indian Academy of Sciences, Bangalore, India
Citation
Journal of Genetics, 2017, 96, 4, pp 535-544
Abstract

I-mfa (inhibitor of the MyoD family a) is a transcription modulator that binds to MyoD family members and inhibits their transcriptional activities. It is highly expressed in the sclerotome and plays an important role in the patterning of the somite early in development. In this study, the...

Author(s)
Huang YongZhen; Li JingJing; Zhang ChunLei; Fang XingTang; Lan XianYong; Qi XingLei; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2016, 27, 4, pp 278-286
Abstract

Copy number variations (CNVs) have been recently recognized as another important genetic variability complementary to single nucleotide polymorphisms (SNPs). Compelling evidence has indicated that CNVs are responsible for phenotypic traits by changing the copy numbers of functional genes. Myosin...

Author(s)
Xu Yao; Shi Tao; Cai HanFang; Zhou Yang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Qi XingLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 535, 2, pp 106-111
Abstract

As an adaptor protein, apart from potentiating Janus kinase 2 (JAK2) activation and promoting the insulin signaling pathway, Src homology 2 B 2 (SH2B2) indirectly takes part in the regulation of glucose uptake through the c-Cb1/CAP/TC10 pathway, which can in turn affect growth. In this study, we...

Author(s)
Yang MingJuan; Fu JunHui; Lan XianYong; Sun YuJia; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 528, 2, pp 314-319
Abstract

Patatin-like phospholipase domain-containing protein 3 (PNPLA3), a member of the patatin like phospholipase domain-containing (PNPLA) family, plays an important role in energy balance, fat metabolism regulation, glucose metabolism and fatty liver disease. Tetra-primer amplification refractory...

Author(s)
Wang ZiNian; Cai HanFang; Li MingXun; Cao XiuKai; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2016, 575, 2 Part 1, pp 191-198
Abstract

The peroxisome proliferator-activated receptor gamma coactivator-1 alpha protein, encoded by the PPARGC1A gene, is a metabolic switch, which transcriptionally activates a complex pathway of mitochondrial biogenesis, lipid and glucose metabolism. Three SNPs (exon 3 c.396G>A, intron 9 c.1892+19C>T...

Author(s)
Li MiJie; Liu Mei; Liu Dong; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 1, pp 39-44
Abstract

The transcription factor paired box 6 gene (PAX6) plays a key role during the early development of various organs. In this study, three single nucleotide polymorphisms (SNPs) have been identified in the introns 2, 8 and 11 of the bovine PAX6 gene. 8 haplotypes and 13 diplotypes were revealed and...

Author(s)
Huang YongZhen; Jing YongJie; Wei TianBao; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2013, 40, 12, pp 6775-6784
Abstract

The aim of this study was to examine the association of the SREBP-1c polymorphism with growth traits in cattle breeds. Five sequence variants (SVs) were identified within the bovine sterol regulatory element-binding protein-1c gene (SREBP-1c), using DNA sequencing, PCR, PCR-RFLP, and forced...

Author(s)
Huang YongZhen; He Hua; Sun JiaJie; Wang Jing; Li ZhuanJian; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Zhang EnPing; Wang JuQiang; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2011, 54, 6, pp 507-516

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