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Abstract

Paired box 7 (PAX7) gene regulates the conversion of muscle satellite cells into myogenic cells and participates in multi-step processes in myogenesis. Expression levels of PAX7 are decisive for its regulatory function. Previous reports revealed that PAX7 were responsible for the developmental...

Author(s)
Xu Yao; Shi Tao; Zhou Yang; Liu Mei; Klaus, S.; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2018, 8, 1, pp 1724
Abstract

The growth and development of muscle is a complex and multistage process, which is regulated by many factors. In particular, genes related to muscle development play a very important role. Studies have shown that there are two kinds of regulatory functions of genes affecting muscle development. One ...

Author(s)
Wen YiFan; He Hua; Song ChengChuang; Peng ShuJun; Lei ChuChao; Chen Hong; Huang YongZhen
Publisher
Guangxi University, Guangxi, China
Citation
Genomics and Applied Biology, 2018, 37, 7, pp 2825-2831
Abstract

Background: Copy number variations (CNVs) are structural variants consisting of large-scale insertions and deletions of genomic fragments. Exploring CNVs and estimating their effects on phenotypes are useful for genome selection but remain challenging in the livestock. Results: We identified 1043...

Author(s)
Liu Mei; Fang LingZhao; Liu ShuLi; Pan, M. G.; Seroussi, E.; Cole, J. B.; Ma Li; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2019, 20, 181, pp (7 March 2019)
Abstract

Identification of polymorphisms associated with economic traits is important for successful marker-assisted selection in cattle breeding. The family of mammalian sirtuin regulates many biological functions, such as life span extension and energy metabolism. SIRT2, a most abundant sirtuin in...

Author(s)
Sun XiaoMei; Li MingXun; Hao Dan; Hua LiuShuai; Lan XianYong; Lei ChuZhao; Hu ShenRong; Qi XingLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2015, 42, 3, pp 729-736
Abstract

Myocyte enhancer factor 2C (MEF2C) gene was annotated for its potential phenotypic effects on bovine stature including body dimensions and body weight. The aim of this study was the analysis of MEF2C as a candidate for bovine stature. Four SNPs including two novel SNPs were identified and the...

Author(s)
Cao XiuKai; Zhan ZhaoYang; Huang YongZhen; Lan XianYong; Lei ChuZhao; Qi XingLei; Chen Hong
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Livestock Science, 2016, 185, pp 106-109
Abstract

Copy number variations (CNVs) recently have been recognized as another important genetic variability followed single nucleotide polymorphisms (SNPs). The guanylate binding protein 2 (GBP2) gene plays an important role in cell proliferation. This study was performed to determine the presence of GBP2 ...

Author(s)
Zhang GuiMin; Zheng Li; He Hua; Song ChengChuang; Zhang ZiJing; Cao XiuKai; Lei ChuZhao; Lan XianYong; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2018, 647, pp 101-106
Abstract

Background: Copy number variation (CNV) is an important type of genetic variation contributing to phenotypic differences among mammals and may serve as an alternative molecular marker to single nucleotide polymorphism (SNP) for genome-wide association study (GWAS). Recently, GWAS analysis using CNV ...

Author(s)
Zhou Yang; Connor, E. E.; Wiggans, G. R.; Lu YongFang; Tempelman, R. J.; Schroeder, S. G.; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2018, 19, 314, pp (2 May 2018)
Abstract

Adipokines play a crucial role in the regulation of energy homeostasis; however, little is known about genetic alterations in this family that may contribute to economic traits in cattle. Therefore, this study conducts transcript profiles, variations and association studies of three major...

Author(s)
Fu WeiWei; Chen NingBo; Han Shuang; Huang JiePing; Li Fen; Hao RuiJie; Chen Hong; Lei ChuZhao; Ma Yun
Publisher
Wiley, Berlin, Germany
Citation
Reproduction in Domestic Animals, 2018, 53, 5, pp 1227-1234
Abstract

Viral infections can play direct or indirect roles in the etiology of the bovine mastitis. Mx dynamin-like GTPase 2 (MX2) gene is a main effector of the antiviral innate immune defense mediated by type I interferon (IFN I), which was demonstrated to confer positive antiviral responses to many...

Author(s)
Chen NingBo; Wang FengQiao; Yu NongQi; Gao Yuan; Huang JiePing; Dang RuiHua; Huang YongZhen; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2018, 29, 2, pp 81-89
Abstract

Cell death-inducing DFFA-like effector c (CIDEC, also known as Fsp27) has emerged as an important regulator of metabolism associated with lipodystrophy, diabetes, and hepatic steatosis. It is required for unilocular lipid droplet formation and optimal energy storage. The mechanism between this gene ...

Author(s)
Wang Jing; Hua LiuShuai; Pan Hong; Zhang LiangZhi; Li MingXun; Huang YongZhen; Li ZhuanJian; Lan XianYong; Lei ChuZhao; Li CongJun; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2015, 5, 1, pp 12075

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