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Abstract

The objective of this study was to examine the association of transient receptor potential vanilloid 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1) genes polymorphisms with growth traits in three Chinese cattle breeds (Jiaxian red cattle, Qinchuan cattle and Luxi cattle). Through...

Author(s)
Wu JiYao; Wang JianJin; Yue BingLin; Fang XingTang; Zhang ChunLei; Ma Yun; Hu LinYong; Bai YueYu; Qi XingShan; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 3, pp 202-211
Abstract

As a member of MYLK family, MYLK4 gene may play a vital role in muscle development. In this study, one novel single-nucleotide polymorphism (SNP) was identified the bovine MYLK4 by sequencing pooled DNA samples (pool-Seq) and forced polymerase chain reaction-restriction fragment length polymorphism ...

Author(s)
Zheng Li; Zhang GuiMin; Dong YanPeng; Wen YiFan; Dong Dong; Lei ChuZhao; Qi XingLei; Chen Hong; Huo LiJun; Huang YongZhen
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 1, pp 30-35
Abstract

Polymorphisms in the prion protein gene (PRNP) have been linked with the occurrence of transmissible spongiform encephalopathies and the expression of some phenotypic traits in healthy animals including cattle. The aim of this study was to verify the 23-bp insertion/deletion (indel) within promoter ...

Author(s)
Yang Qing; Zhang SiHuan; Liu LiangLiang; Lei ChuZhao; Qi XingLei; Lin FengPeng; Qu WeiDong; Qi XingShan; Liu JiMing; Wang RongMin; Chen Hong; Lan XianYong
Publisher
Taylor & Francis, Abingdon, UK
Citation
Journal of Applied Animal Research, 2018, 46, 1, pp 505-511
Abstract

CNV1 and CNV2 of the GBP2 gene in 80 Qinchuan and 30 Jiaxian red cattle were detected by using quantitative real-time PCR (qPCR), respectively, to examine the variation of copy number and genetic effects of the GBP2 gene in Chinese cattle and the correlation of 2 CNV regions of GBP2 gene variation...

Author(s)
Zhang GuiMin; He Hua; Zheng Li; Song ChengChuang; Cao XiuKai; Wen YiFan; Lu QianQian; Lei ChuChao; Chen Hong; Huang YongZhen
Publisher
Guoji Shudian (Institute of Scientific and Technological Information of China, China Publications Centre), Beijing, China
Citation
Chinese Journal of Animal Science, 2018, 54, 1, pp 51-54, 64
Abstract

Our previous work reported a relationship between FOXO1 mutations and growth of Qinchuan (QC) cattle. Here, we performed differential expression analysis of FOXO1 and its association analysis with growth traits in QC cattle. First, we measured the expression of the FOXO1 gene in nine tissues during ...

Author(s)
Sun YuJia; Liu KunPeng; Huang YongZhen; Lan XianYong; Chen Hong
Publisher
Science China Press, co-published with Springer, Berlin, Germany
Citation
Science China Life Sciences, 2018, 61, 7, pp 826-835
Abstract

Sonic Hedgehog (Shh) regulates many key developmental processes during vertebrate limb development, fat formation, and skeletal tissue regeneration. Current whole genome sequencing data have identified a copy number variation mapping to bovine Sonic Hedgehog gene (SHH-CNV). The object of this study ...

Author(s)
Liu Mei; Li Bo; Shi Tao; Huang YongZhen; Liu, G. E.; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Journal of Applied Genetics, 2019, 60, 2, pp 199-207
Abstract

Current evidences show that copy number variations (CNVs) are linked to complex phenotypic traits. Leptin receptor (LEPR) gene plays a critical role in energy homeostasis and fat development and re-sequencing of the cattle genome revealed the CNV region (herein referred to as "I3 DNA") within the ...

Author(s)
Shi Tao; Xu Yao; Yang MingJuan; Huang YongZhen; Lan XianYong; Lei ChuZhao; Qi XingLei; Yang XiaoMing; Chen Hong
Publisher
Wiley-Blackwell, Melbourne, Australia
Citation
Animal Science Journal, 2016, 87, 3, pp 336-343
Abstract

Copy number variation is a large genome variation which usually happens in the noncoding-region, and it may occur at the locus associated with the functional gene to further influence the phenotype. Potassium inwardly-rectifying channel, subfamily J 12 (KCNJ12) gene expressed widely in...

Author(s)
Zheng Li; Xu JiaWei; Li JiChao; Wang DaHui; An QingMing; Xu LinNa; Ma YiLei; Wang Jian; Peng ShuJun; Lei ChuZhao; Lan XianYong; Chen Hong; Huo LiJun; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 689, pp 90-96
Abstract

The α-adducin (ADD1) is a subunit of adducin which is a cytoskeleton heterodimeric protein. Adducin participates in oocytes chromosome meiosis of mice, prompting adducin has an effect on embryonic development. Adducin gene mutation has significantly functional change. So the present study was to...

Author(s)
Huang YongZhen; Qian LiNa; Wang Jian; Zhang ChunLei; Fang XingTang; Lei ChuZhao; Lan XianYong; Ma Yun; Bai YueYu; Lin FengPeng; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 1, pp 7-12
Abstract

Pituitary homeobox 2 (PITX2) plays crucial roles in embryogenesis, ontogenesis, growth, and development via the Wnt/beta-catenin and POU1F1 pathways. To better understand the characteristics and genetic effects of the cattle PITX2 gene, we identified alternative PITX2 splicings, examined the...

Author(s)
Zhang SiHuan; Xu Han; Kang ZiHong; Cai HanFang; Dang RuiHua; Lei ChuZhao; Chen Hong; Guo Xian; Lan XianYong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2018, 669, pp 1-7

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