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Abstract

The objective of this study was to examine the association of transient receptor potential vanilloid 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1) genes polymorphisms with growth traits in three Chinese cattle breeds (Jiaxian red cattle, Qinchuan cattle and Luxi cattle). Through...

Author(s)
Wu JiYao; Wang JianJin; Yue BingLin; Fang XingTang; Zhang ChunLei; Ma Yun; Hu LinYong; Bai YueYu; Qi XingShan; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 3, pp 202-211
Abstract

As a member of MYLK family, MYLK4 gene may play a vital role in muscle development. In this study, one novel single-nucleotide polymorphism (SNP) was identified the bovine MYLK4 by sequencing pooled DNA samples (pool-Seq) and forced polymerase chain reaction-restriction fragment length polymorphism ...

Author(s)
Zheng Li; Zhang GuiMin; Dong YanPeng; Wen YiFan; Dong Dong; Lei ChuZhao; Qi XingLei; Chen Hong; Huo LiJun; Huang YongZhen
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 1, pp 30-35
Abstract

Adipocyte differentiation-associated long noncoding RNA (ADNCR) is a newly discovered lncRNA. It plays function by targeting miR-204 to significantly regulates the expression of the target SIRT1 gene in preadipocytes both at the level of mRNA and protein, thereby inhibiting adipogenesis. The...

Author(s)
Jin YunYun; Yang Qing; Zhang Meng; Zhang SiHuan; Cai HanFang; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 2, pp 159-165
Abstract

Our previous work reported a relationship between FOXO1 mutations and growth of Qinchuan (QC) cattle. Here, we performed differential expression analysis of FOXO1 and its association analysis with growth traits in QC cattle. First, we measured the expression of the FOXO1 gene in nine tissues during ...

Author(s)
Sun YuJia; Liu KunPeng; Huang YongZhen; Lan XianYong; Chen Hong
Publisher
Science China Press, co-published with Springer, Berlin, Germany
Citation
Science China Life Sciences, 2018, 61, 7, pp 826-835
Abstract

Adipose tissue plays central role in determining the gustatory quality of beef, but traditional Chinese beef cattle have low levels of fat content. We applied RNA-seq to study the molecular mechanisms underlying adipocyte differentiation in Qinchuan cattle. A total of 18,283 genes were found to be...

Author(s)
Cai HanFang; Li MingXun; Sun XiaoMei; Plath, M.; Li CongJun; Lan XianYong; Lei ChuZhao; Huang YongZhen; Bai YueYu; Qi XingLei; Lin FengPeng; Chen Hong
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Genetics, 2018, 9, October, pp 463
Abstract

SMAD3, the messenger of the transforming growth factor beta (TGF-β) signaling pathway, plays essential roles in myogenesis and osteogenesis and may relate to the regulation of body weight. In this study, a 17 bp indel (NC_007308: g.101893_101909 insGAGGATGAGTGCTCCAG) in intron3 of the SMAD3 gene...

Author(s)
Shi Tao; Peng WenWen; Yan JianYu; Cai HanFang; Lan XianYong; Lei ChuZhao; Bai YueYu; Chen Hong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 1, pp 151-157
Abstract

Copy number variation (CNV) is a main and prevalent structural alterations underlying evolution of animal, which is considered to affect gene expression and complex traits. In this study, we analyzed genomic characteristics of CNV regions (CNVRs) in 254 Qinchuan cattle using GeneSeek HD 77k...

Author(s)
Huang JiePing; Li Ran; Zhang Xin; Huang YongZhen; Dang RuiHua; Lan XianYong; Chen Hong; Lei ChuZhao
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Livestock Science, 2017, 204, pp 88-91
Abstract

Paired box 7 (Pax7) gene, a member of the paired box gene family, plays a critical role in animal growth and muscle development, especially in cell proliferation and self-renewal. The aim of this study was to detect the 10 base pair (bp) duplication insertion/deletion (indel) in the promoter region ...

Author(s)
Jin YunYun; Cai HanFang; Liu JiMing; Lin FengPeng; Qi XingLei; Bai YueYu; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 4, pp 469-476
Abstract

Current evidences show that copy number variations (CNVs) are linked to complex phenotypic traits. Leptin receptor (LEPR) gene plays a critical role in energy homeostasis and fat development and re-sequencing of the cattle genome revealed the CNV region (herein referred to as "I3 DNA") within the ...

Author(s)
Shi Tao; Xu Yao; Yang MingJuan; Huang YongZhen; Lan XianYong; Lei ChuZhao; Qi XingLei; Yang XiaoMing; Chen Hong
Publisher
Wiley-Blackwell, Melbourne, Australia
Citation
Animal Science Journal, 2016, 87, 3, pp 336-343
Abstract

I-mfa (inhibitor of the MyoD family a) is a transcription modulator that binds to MyoD family members and inhibits their transcriptional activities. It is highly expressed in the sclerotome and plays an important role in the patterning of the somite early in development. In this study, the...

Author(s)
Huang YongZhen; Li JingJing; Zhang ChunLei; Fang XingTang; Lan XianYong; Qi XingLei; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2016, 27, 4, pp 278-286

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