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Veterinary information to support practice, based on evidence and continuing education

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Abstract

WNT-β-Catenin-TCF pathway is involved in carcinogenesis and foetal development. As a member of the WNT gene family, Wnt8A encodes secreted signalling proteins and responds to many biological processes. However, similar research on the effects of genetic variations of Wnt8A gene on growth traits is...

Author(s)
Huang YongZhen; Zou Yong; Lin Qing; He Hua; Zheng Li; Zhang ZiJing; Dang YongLong; Lei ChuZhao; Lan XianYong; Qi XingShan; Chen Hong
Publisher
Indian Academy of Sciences, Bangalore, India
Citation
Journal of Genetics, 2017, 96, 4, pp 535-544
Abstract

Chinese indigenous cattle breeds have abundant genetic resources, which are valuable for the molecular breeding of cattle around the world. Thus, identifying important candidate genes and their genetic markers is very important for cattle molecular breeding. A previous study found that a nonsense...

Author(s)
Zhang SiHuan; Peng Kun; Zhang GuoLiang; Cao Yang; Zhang Meng; Chen Hong; Lei ChuZhao; Lan XianYong; Zhao YuMin
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2019, 9, 7, pp 444
Abstract

Flightless-1 (FLII) is essential for early embryogenesis, structural organization of indirect flight muscle and can inhibit adipocyte differentiation. We therefore aimed to identify common variations in FLII gene and to investigate their effects on cattle growth traits. By DNA sequencing and forced ...

Author(s)
Liu Mei; Liu Min; Li Bo; Zhou Yang; Huang YongZhen; Lan XianYong; Qu WeiDong; Qi XingShan; Bai YueYu; Chen Hong
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Molecular and Cellular Probes, 2016, 30, 4, pp 266-272
Abstract

Monoacylglycerol acyltransferase (MGAT3, also known as MOGAT3) catalyzes the synthesis of diacylglycerol (DAG) using 2-monoacylglycerol and fatty acyl coenzyme A. This enzymatic reaction is believed to be an essential and rate-limiting step for the absorption of dietary fat in the small intestine....

Author(s)
Sun JiaJie; Zhang ChunLei; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2012, 55, 1, pp 56-62
Abstract

The aim of this study was to detect mutations of the nuclear factor I/X (Nfix) gene and examine the association of its polymorphisms with growth traits in cattle. Six sequence variants (SVs) including five single-nucleotide mutations and an indel with multiple alleles were detected, among which...

Author(s)
Zhou Yang; Lan XianYong; Xu Yao; Zhang Bao; Li MiJie; Huang YongZhen; Sun JiaJie; Cai HanFang; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2012, 55, 12, pp 845-851
Abstract

Wingless-type MMTV integration site family, member 10B (WNT10B) may play an important role in inhibiting differentiation of preadipocytes in vitro and impairing adipose development in vivo. In this study, based on DNA sequencing and PCR-RFLP methods, we attempted to characterize the associations...

Author(s)
Zhao Jing; Zhang CunLei; Fang XingTang; Zhang HaiYan; Liu XuanXuan; Li JingJing; Liu Yao; Yang DongYing; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2012, 93, 3, pp 1301-1306
Abstract

The F-box protein 32 (FBXO32), also known as Atrogin-1, is one of the four subunits of the ubiquitin protein ligase complex. FBXO32 has been previously shown to be involved in regulation of initiation and development of muscle mass. In the present study, we investigated the polymorphism of FBXO32...

Author(s)
Wang AiLan; Zhang Ya; Li MiJie; Lan XianYong; Wang JuQiang; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 515, 1, pp 181-186
Abstract

The peroxisome proliferator-activated receptor gamma coactivator-1 alpha protein, encoded by the PPARGC1A gene, is a metabolic switch, which transcriptionally activates a complex pathway of mitochondrial biogenesis, lipid and glucose metabolism. Three SNPs (exon 3 c.396G>A, intron 9 c.1892+19C>T...

Author(s)
Li MiJie; Liu Mei; Liu Dong; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 1, pp 39-44
Abstract

Zinc finger, BED-type containing 6 (ZBED6) is a novel transcription factor that was identified and shown to act as a repressor of IGF2 transcription in skeletal muscle myogenesis and development. The aims of this study were to determine ZBED6 expression level and examine the association of the ...

Author(s)
Huang YongZhen; Sun YuJia; Zhan ZhaoYang; Li MingXun; Wang Jing; Xue Jing; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2014, 25, 1, pp 35-54
Abstract

Background: Identification of genetic variants, including SNPs (Single Nucleotide Polymorphisms), CNVs (Copy Number Variations) and alternative splicing, within functional genes has received increasing attention in animal science research. HGF (Hepatocyte Growth Factor) is a very important growth...

Author(s)
Cai HanFang; Zhou Yang; Jia WenChao; Zhang BoWen; Lan XianYong; Lei ChuZhao; Fang XinTang; Chen Hong
Publisher
BioMed Central Ltd, London, UK
Citation
Journal of Animal Science and Biotechnology, 2015, 6, 55, pp (22 December 2015)

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