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VetMed Resource

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Abstract

SMAD3, the messenger of the transforming growth factor beta (TGF-β) signaling pathway, plays essential roles in myogenesis and osteogenesis and may relate to the regulation of body weight. In this study, a 17 bp indel (NC_007308: g.101893_101909 insGAGGATGAGTGCTCCAG) in intron3 of the SMAD3 gene...

Author(s)
Shi Tao; Peng WenWen; Yan JianYu; Cai HanFang; Lan XianYong; Lei ChuZhao; Bai YueYu; Chen Hong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 1, pp 151-157
Abstract

Paired-like homeodomain transcription factor 1 (PITX1) is a pivotal gene in the hypothalamic-pituitary-adrenal axis, which is a well-known pathway affecting lactation performance. The aim of this study was to analyze the DNA methylation profile of the PITX1 gene and its relevance to milk...

Author(s)
Zhao HaiYu; Zhang SiHuan; Wu XianFeng; Pan ChuanYing; Li XiangChen; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2019, 62, 1, pp 59-68
Abstract

I-mfa (inhibitor of the MyoD family a) is a transcription modulator that binds to MyoD family members and inhibits their transcriptional activities. It is highly expressed in the sclerotome and plays an important role in the patterning of the somite early in development. In this study, the...

Author(s)
Huang YongZhen; Li JingJing; Zhang ChunLei; Fang XingTang; Lan XianYong; Qi XingLei; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2016, 27, 4, pp 278-286
Abstract

AT motif binding factor 1 (ATBF1) gene can promote the expression level of the growth hormone 1 (GH1) gene by binding to the enhancers of the POU1F1 and PROP1 genes; thus, it affects the growth and development of livestock. Considering that the ATBF1 gene also has a close relationship with the...

Author(s)
Xu Han; Zhang SiHuan; Zhang XiaoYan; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2017, 60, 3, pp 285-296
Abstract

The PROP1 protein, encoded by the prophet of Pit-1 (PROP1) gene, exhibits both DNA-binding and transcriptional activation abilities. Its expression leads to the ontogenesis of growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (TSH), and pituitary hormone. The missense mutation H173R ...

Author(s)
Pan ChuanYing; Wu ChongYang; Jia WenChao; Xu Yao; Lei ChuZhao; Hu ShenRong; Lan XianYong; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 531, 2, pp 398-402
Abstract

SIRT1, a mammalian homologue for yeast silent information regulator 2 (SIR2), is a NAD+-dependent deacetylase that belongs to the class III histone deacetylases. It plays an important role in diverse cellular processes, including stress resistance, mitochondrial function, suppression of...

Author(s)
Li MingXun; Sun XiaoMei; Zhang LiangZhi; Wang Jing; Huang YongZhen; Sun YuJia; Hu ShenRong; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Animal Genetics, 2013, 44, 5, pp 584-587
AbstractFull Text

Through shot-gun method, one hundred and three DNA segments of promoter from genomic library of 168 Bacillus subtilis were detected with Escherichia coli-B. subtilis shuttle plasmid. The activities of the reporter gene of bgaB driven by one promoter fragment, P3.4.23, exhibited high expression...

Author(s)
Zhang AiLing; Zhang Li; Yang MingMing; Zhang LiangZhi; Chen Hong
Publisher
South China Agricultural University, Guangzhou, China
Citation
Journal of South China Agricultural University, 2011, 32, 3, pp 92-96
Abstract

The insulin-induced gene 1 (INSIG1) gene encodes a protein that blocks proteolytic activation of sterol regulatory element binding proteins, which are transcription factors that activate genes that regulate cholesterol, fatty acid, and glucose metabolism. However, similar research for the bovine ...

Author(s)
Sun JiaJie; Gao Yuan; Liu Dong; Ma Wei; Xue Jing; Zhang ChunLei; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2012, 55, 6, pp 429-436

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