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Veterinary information to support practice, based on evidence and continuing education

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Abstract

Sonic Hedgehog (Shh) regulates many key developmental processes during vertebrate limb development, fat formation, and skeletal tissue regeneration. Current whole genome sequencing data have identified a copy number variation mapping to bovine Sonic Hedgehog gene (SHH-CNV). The object of this study ...

Author(s)
Liu Mei; Li Bo; Shi Tao; Huang YongZhen; Liu, G. E.; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Journal of Applied Genetics, 2019, 60, 2, pp 199-207
Abstract

Copy number variations (CNVs) recently have been recognized as another important genetic variability followed single nucleotide polymorphisms (SNPs). The guanylate binding protein 2 (GBP2) gene plays an important role in cell proliferation. This study was performed to determine the presence of GBP2 ...

Author(s)
Zhang GuiMin; Zheng Li; He Hua; Song ChengChuang; Zhang ZiJing; Cao XiuKai; Lei ChuZhao; Lan XianYong; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2018, 647, pp 101-106
Abstract

Copy number variations (CNVs) recently have been recognized as an important source of genetic variability. Compelling evidence has indicated that CNVs are responsible for phenotypic traits by altering the copy numbers of functional genes. The molecule interacting with CasL-like protein 2 (MICAL-L2) ...

Author(s)
Xu Yao; Zhang LiangZhi; Shi Tao; Zhou Yang; Cai HanFang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
Springer, New York, USA
Citation
Mammalian Genome, 2013, 24, 11/12, pp 508-516
Abstract

The peroxisome proliferator-activated receptor gamma coactivator-1 alpha protein, encoded by the PPARGC1A gene, is a metabolic switch, which transcriptionally activates a complex pathway of mitochondrial biogenesis, lipid and glucose metabolism. Three SNPs (exon 3 c.396G>A, intron 9 c.1892+19C>T...

Author(s)
Li MiJie; Liu Mei; Liu Dong; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 1, pp 39-44
AbstractFull Text

In the process of anterior pituitary gland development and maturation, numerous transcription factors were involved in the pituitary organogenesis. To date, the lack of knowledge on POU1F1-PROP1-PITX1-SIX3 pathway genes affecting growth traits was reported in Chinese goat breeds. The objective of...

Author(s)
Ma Lin; Qin QiaoMei; Yang Qing; Zhang Meng; Zhao HaiYu; Pan ChuanYing; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
National Research Institute of Animal Production, Kraków, Poland
Citation
Annals of Animal Science, 2017, 17, 2, pp 399-411
Abstract

Adiponectin modulates lipid and glucose metabolism in adipose tissues and is also related to bone metabolism. Polymorphisms in the ADIPOQ gene likely have an impact on growth traits in cattle. In this study, we examined the relationship between ADIPOQ polymorphisms and body measurement parameters...

Author(s)
Zhang LiangZhi; Li MiJie; Lai XinSheng; Yang MingJuan; Xu Yao; Hua LiuShuai; Lan XianYong; Zhang ChunLei; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 7, pp 389-394
Abstract

The transcription factor paired box 6 gene (PAX6) plays a key role during the early development of various organs. In this study, three single nucleotide polymorphisms (SNPs) have been identified in the introns 2, 8 and 11 of the bovine PAX6 gene. 8 haplotypes and 13 diplotypes were revealed and...

Author(s)
Huang YongZhen; Jing YongJie; Wei TianBao; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2013, 40, 12, pp 6775-6784
Abstract

The AT motif-binding factor (ATBF1) not only interacts with protein inhibitor of activated signal transducer and activator of transcription 3 (STAT3) (PIAS3) to suppress STAT3 signaling regulating embryo early development and cell differentiation, but is required for early activation of the...

Author(s)
Zhang XiaoYan; Wu XianFeng; Jia WenChao; Pan ChuanYing; Li XiangCheng; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Asian-Australasian Association of Animal Production Societies, Seoul, Korea Republic
Citation
Asian-Australasian Journal of Animal Sciences, 2015, 28, 10, pp 1394-1406
Abstract

The insulin-induced gene 1 (INSIG1) gene encodes a protein that blocks proteolytic activation of sterol regulatory element binding proteins, which are transcription factors that activate genes that regulate cholesterol, fatty acid, and glucose metabolism. However, similar research for the bovine ...

Author(s)
Sun JiaJie; Gao Yuan; Liu Dong; Ma Wei; Xue Jing; Zhang ChunLei; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2012, 55, 6, pp 429-436
Abstract

Signal transducer and activator of transcription 5A (STAT5A), previously known as mammary gland factor (MGF), belongs to the prolactin/JAK2/STAT5 pathway, and plays an important role in growth and development, milking, and lipid accumulation in mammals. The aim of this study was to identify novel...

Author(s)
Wu XianFeng; Jia WenChao; Zhang JingJing; Li XiangCheng; Pan ChuanYing; Lei ChuZhao; Chen Hong; Dang RuiHua; Lan XianYong
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Small Ruminant Research, 2014, 121, 2/3, pp 232-243

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