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Abstract

As a member of MYLK family, MYLK4 gene may play a vital role in muscle development. In this study, one novel single-nucleotide polymorphism (SNP) was identified the bovine MYLK4 by sequencing pooled DNA samples (pool-Seq) and forced polymerase chain reaction-restriction fragment length polymorphism ...

Author(s)
Zheng Li; Zhang GuiMin; Dong YanPeng; Wen YiFan; Dong Dong; Lei ChuZhao; Qi XingLei; Chen Hong; Huo LiJun; Huang YongZhen
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 1, pp 30-35
Abstract

Adipocyte differentiation-associated long noncoding RNA (ADNCR) is a newly discovered lncRNA. It plays function by targeting miR-204 to significantly regulates the expression of the target SIRT1 gene in preadipocytes both at the level of mRNA and protein, thereby inhibiting adipogenesis. The...

Author(s)
Jin YunYun; Yang Qing; Zhang Meng; Zhang SiHuan; Cai HanFang; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 2, pp 159-165
Abstract

In this study, we detected the polymorphism of SNPs of intron 6 in CAPN4 gene in Datong Yak, Tianzhu White Yak, Gannan Yak and cattle by PCR-SSCP and DNA sequencing in order to understand the genetic characters of this gene in yak and cattle. The results showed that the 6 intron of CAPN4 gene in...

Author(s)
Zhang Li; Liu LiXia; Chen Hong; Yu LingXiao
Publisher
Guangxi University, Guangxi, China
Citation
Genomics and Applied Biology, 2017, 36, 12, pp 5099-5103
Abstract

SMAD3, the messenger of the transforming growth factor beta (TGF-β) signaling pathway, plays essential roles in myogenesis and osteogenesis and may relate to the regulation of body weight. In this study, a 17 bp indel (NC_007308: g.101893_101909 insGAGGATGAGTGCTCCAG) in intron3 of the SMAD3 gene...

Author(s)
Shi Tao; Peng WenWen; Yan JianYu; Cai HanFang; Lan XianYong; Lei ChuZhao; Bai YueYu; Chen Hong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 1, pp 151-157
Abstract

NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair regeneration of skeletal muscles. However, similar research on the bovine ...

Author(s)
Liu Mei; Zhang ChenGe; Lai XinSheng; Xue Jing; Lan XianYong; Lei ChuZhao; Jia YuTang; Chen Hong
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Journal of Applied Genetics, 2017, 58, 2, pp 241-247
Abstract

Paired-like homeodomain transcription factor 1 (PITX1) is a pivotal gene in the hypothalamic-pituitary-adrenal axis, which is a well-known pathway affecting lactation performance. The aim of this study was to analyze the DNA methylation profile of the PITX1 gene and its relevance to milk...

Author(s)
Zhao HaiYu; Zhang SiHuan; Wu XianFeng; Pan ChuanYing; Li XiangChen; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2019, 62, 1, pp 59-68
Abstract

Paired box 7 (Pax7) gene, a member of the paired box gene family, plays a critical role in animal growth and muscle development, especially in cell proliferation and self-renewal. The aim of this study was to detect the 10 base pair (bp) duplication insertion/deletion (indel) in the promoter region ...

Author(s)
Jin YunYun; Cai HanFang; Liu JiMing; Lin FengPeng; Qi XingLei; Bai YueYu; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 4, pp 469-476
Abstract

Current evidences show that copy number variations (CNVs) are linked to complex phenotypic traits. Leptin receptor (LEPR) gene plays a critical role in energy homeostasis and fat development and re-sequencing of the cattle genome revealed the CNV region (herein referred to as "I3 DNA") within the ...

Author(s)
Shi Tao; Xu Yao; Yang MingJuan; Huang YongZhen; Lan XianYong; Lei ChuZhao; Qi XingLei; Yang XiaoMing; Chen Hong
Publisher
Wiley-Blackwell, Melbourne, Australia
Citation
Animal Science Journal, 2016, 87, 3, pp 336-343
Abstract

I-mfa (inhibitor of the MyoD family a) is a transcription modulator that binds to MyoD family members and inhibits their transcriptional activities. It is highly expressed in the sclerotome and plays an important role in the patterning of the somite early in development. In this study, the...

Author(s)
Huang YongZhen; Li JingJing; Zhang ChunLei; Fang XingTang; Lan XianYong; Qi XingLei; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2016, 27, 4, pp 278-286
Abstract

The α-adducin (ADD1) is a subunit of adducin which is a cytoskeleton heterodimeric protein. Adducin participates in oocytes chromosome meiosis of mice, prompting adducin has an effect on embryonic development. Adducin gene mutation has significantly functional change. So the present study was to...

Author(s)
Huang YongZhen; Qian LiNa; Wang Jian; Zhang ChunLei; Fang XingTang; Lei ChuZhao; Lan XianYong; Ma Yun; Bai YueYu; Lin FengPeng; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 1, pp 7-12

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