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Abstract

Background: Copy number variation (CNV) is an important type of genetic variation contributing to phenotypic differences among mammals and may serve as an alternative molecular marker to single nucleotide polymorphism (SNP) for genome-wide association study (GWAS). Recently, GWAS analysis using CNV ...

Author(s)
Zhou Yang; Connor, E. E.; Wiggans, G. R.; Lu YongFang; Tempelman, R. J.; Schroeder, S. G.; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2018, 19, 314, pp (2 May 2018)
Abstract

SIRT1, a mammalian homologue for yeast silent information regulator 2 (SIR2), is a NAD+-dependent deacetylase that belongs to the class III histone deacetylases. It plays an important role in diverse cellular processes, including stress resistance, mitochondrial function, suppression of...

Author(s)
Li MingXun; Sun XiaoMei; Zhang LiangZhi; Wang Jing; Huang YongZhen; Sun YuJia; Hu ShenRong; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Animal Genetics, 2013, 44, 5, pp 584-587
Abstract

Adipose differentiation-related protein (ADFP) is important for regulation of lipid metabolism and insulin secretion in beta-cells. In this study, we investigated polymorphisms within the caprine ADFP gene and determined its relationship with production traits. As there was no sequence information...

Author(s)
Li ZhuanJian; Guo WenJiao; Tian YaDong; Han RuiLi; Sun YuJia; Xue Jing; Lan XianYong; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 538, 2, pp 244-250
Abstract

The AT motif-binding factor (ATBF1) not only interacts with protein inhibitor of activated signal transducer and activator of transcription 3 (STAT3) (PIAS3) to suppress STAT3 signaling regulating embryo early development and cell differentiation, but is required for early activation of the...

Author(s)
Zhang XiaoYan; Wu XianFeng; Jia WenChao; Pan ChuanYing; Li XiangCheng; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Asian-Australasian Association of Animal Production Societies, Seoul, Korea Republic
Citation
Asian-Australasian Journal of Animal Sciences, 2015, 28, 10, pp 1394-1406
Abstract

Signal transducer and activator of transcription 5A (STAT5A), previously known as mammary gland factor (MGF), belongs to the prolactin/JAK2/STAT5 pathway, and plays an important role in growth and development, milking, and lipid accumulation in mammals. The aim of this study was to identify novel...

Author(s)
Wu XianFeng; Jia WenChao; Zhang JingJing; Li XiangCheng; Pan ChuanYing; Lei ChuZhao; Chen Hong; Dang RuiHua; Lan XianYong
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Small Ruminant Research, 2014, 121, 2/3, pp 232-243

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