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Abstract

Our previous work reported a relationship between FOXO1 mutations and growth of Qinchuan (QC) cattle. Here, we performed differential expression analysis of FOXO1 and its association analysis with growth traits in QC cattle. First, we measured the expression of the FOXO1 gene in nine tissues during ...

Author(s)
Sun YuJia; Liu KunPeng; Huang YongZhen; Lan XianYong; Chen Hong
Publisher
Science China Press, co-published with Springer, Berlin, Germany
Citation
Science China Life Sciences, 2018, 61, 7, pp 826-835
Abstract

Circular RNA (circRNA) is a new class of non-coding RNA that has recently attracted researchers' interest. Studies have demonstrated that circRNA can function as microRNA sponges or competing endogenous RNAs. Although circRNA has been explored in some species and tissues, the genetic basis of...

Author(s)
Gao Yuan; Wu MingLi; Fan YingZhi; Li ShiPeng; Lai ZhenYu; Huang YongZhen; Lan XianYong; Lei ChuZhao; Chen Hong; Dang RuiHua
Publisher
Royal Society, London, UK
Citation
Royal Society Open Science, 2018, 5, 7, pp 180413
Abstract

MiRNAs have emerged as key regulators of skeletal muscle development, but the knowledge of miRNAs in the molecular network of muscle development remains poorly understood. In this study, we designed to examine the biological function of bovine-miR-101-1. The bovine miR-101-1 was detected in the...

Author(s)
Wu JiYao; He DanDan; Yue BingLin; Zhang ChunLei; Fang XingTang; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2017, 636, pp 64-69
Abstract

NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair regeneration of skeletal muscles. However, similar research on the bovine ...

Author(s)
Liu Mei; Zhang ChenGe; Lai XinSheng; Xue Jing; Lan XianYong; Lei ChuZhao; Jia YuTang; Chen Hong
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Journal of Applied Genetics, 2017, 58, 2, pp 241-247
Abstract

Sonic Hedgehog (Shh) regulates many key developmental processes during vertebrate limb development, fat formation, and skeletal tissue regeneration. Current whole genome sequencing data have identified a copy number variation mapping to bovine Sonic Hedgehog gene (SHH-CNV). The object of this study ...

Author(s)
Liu Mei; Li Bo; Shi Tao; Huang YongZhen; Liu, G. E.; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Journal of Applied Genetics, 2019, 60, 2, pp 199-207
Abstract

The aim of this study was to examine the association of cofilin2 (CFL2) gene polymorphisms with growth traits in Chinese Qinchuan cattle. Three single nucleotide polymorphisms (SNPs) were identified in the bovine CFL2 gene using DNA sequencing and (forced) PCR-RFLP methods. These polymorphisms...

Author(s)
Sun YuJia; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2015, 563, 2, pp 136-141
Abstract

NPC1 gene is an important gene closely related to the Niemann-Pick type C (NPC). Mutations in the NPC1 gene tend to cause Niemann-Pick type C, a lysosomal storage disorder. Previous studies have shown that NPC1 protein plays an important role in subcellular lipid transport, homeostasis, platelet...

Author(s)
Dang YongLong; Li MingXun; Yang MingJuan; Cao XiuKai; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Lin Qing; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 540, 2, pp 153-160
Abstract

DNA methylation is a key epigenetic modification in mammals and plays important roles in muscle development. We sampled longissimus dorsi muscle (LDM) from a well-known elite native breed of Chinese Qinchuan cattle living within the same environment but displaying distinct skeletal muscle at the...

Author(s)
Huang YongZhen; Sun JiaJie; Zhang LiangZhi; Li CongJun; Womack, J. E.; Li ZhuanJian; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Zhao Xin; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2014, 4, 1, pp 06546
Abstract

The Pit-1 gene was studied as a candidate for genetic markers of growth traits in Chinese cattle in this study. The single-strand conformation polymorphism method was used to identify polymorphism in the Pit-1 intron 5. One single nucleotide polymorphism, Pit1I5, was found in intron 5. The...

Author(s)
Tang LiGang; Yang DongYing; Ouyang WuQing; Zhang LiangZhi; Lan XianYong; Zhang ChunLei; Zhang RunFeng; Zhang AiLing; Zhang Li; Chen Hong
Publisher
Academic Journals, Nairobi, Kenya
Citation
African Journal of Biotechnology, 2012, 11, 42, pp 9906-9910
Abstract

PCR-RFLP was applied to analyse the polymorphisms of H-FABP gene in 164 beef cattle aged 4 months (±10 days) comprised of Qinchuan (QQ), Qinchuan × Limousin (LQ), Qinchuan × Red Angus (AQ) and Qinchuan × German Yellow breeds (DQ). The results showed that 2071 bp PCR products digested with HaeIII...

Author(s)
Xue Kai; Chen Hong; Wang Shan; Cai Xin; Fang XingTang
Publisher
Asian Network for Biotechnology in Animal Production and Health, Haidian, China
Citation
Animal Biotechnology Bulletin, 2006, 10, 1, pp 426-429

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