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Abstract

Sonic Hedgehog (Shh) regulates many key developmental processes during vertebrate limb development, fat formation, and skeletal tissue regeneration. Current whole genome sequencing data have identified a copy number variation mapping to bovine Sonic Hedgehog gene (SHH-CNV). The object of this study ...

Author(s)
Liu Mei; Li Bo; Shi Tao; Huang YongZhen; Liu, G. E.; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Journal of Applied Genetics, 2019, 60, 2, pp 199-207
Abstract

Identification of polymorphisms associated with economic traits is important for successful marker-assisted selection in cattle breeding. The family of mammalian sirtuin regulates many biological functions, such as life span extension and energy metabolism. SIRT2, a most abundant sirtuin in...

Author(s)
Sun XiaoMei; Li MingXun; Hao Dan; Hua LiuShuai; Lan XianYong; Lei ChuZhao; Hu ShenRong; Qi XingLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2015, 42, 3, pp 729-736
Abstract

LIM homeobox transcription factor 4 (LHX4) is a LIM homeodomain transcription factor involved in pituitary gland and nervous system development. The aim of this study was to examine the association of the LHX4 polymorphisms with growth traits in beef cattle breed. A total of 7 single nucleotide...

Author(s)
Ren Gang; Huang YongZhen; Wei TianBao; Liu JunXia; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Zhang ZhiYing; Qi XingLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 538, 2, pp 354-360
Abstract

The glioma-associated oncogene family zinc finger 3 gene (GLI3) mediates in all vertebrates hedgehog (Hh) signaling that plays an essential role in the induction and patterning of numerous cell types during invertebrate and vertebrate development. In this study, a total of 6 single nucleotide...

Author(s)
Huang YongZhen; Wang KeYi; He Hua; Shen QingWu; Lei ChuZhao; Lan XianYong; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 513, 1, pp 141-146
Abstract

The paired box 7 (Pax7) gene encoding for the transcription factor can regulate the conversion of stem cells into myogenic cells and participate in the development and regeneration of skeletal muscle. The aims of this study were to detect variations of the Pax7 gene by DNA pool sequencing and...

Author(s)
Xu Yao; Zhou Yang; Wang Ning; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 1, pp 9-15
Abstract

The Pit-1 gene was studied as a candidate for genetic markers of growth traits in Chinese cattle in this study. The single-strand conformation polymorphism method was used to identify polymorphism in the Pit-1 intron 5. One single nucleotide polymorphism, Pit1I5, was found in intron 5. The...

Author(s)
Tang LiGang; Yang DongYing; Ouyang WuQing; Zhang LiangZhi; Lan XianYong; Zhang ChunLei; Zhang RunFeng; Zhang AiLing; Zhang Li; Chen Hong
Publisher
Academic Journals, Nairobi, Kenya
Citation
African Journal of Biotechnology, 2012, 11, 42, pp 9906-9910
Abstract

Growth is under complex genetic control and uncovering the molecular mechanisms how the genes and polymorphisms affect economic growth traits, are important for successful marker-assisted selection and more efficient management strategies in commercial cattle populations. SIRT1 is a NAD+-dependent...

Author(s)
Li MingXun; Sun XiaoMei; Hua LiuShuai; Lai XinSheng; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Qi XingLei; Chen Hong
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Molecular and Cellular Probes, 2013, 27, 5/6, pp 215-220
Abstract

The myostatin (GDF-8) acts as a negative regulator of muscle growth. Mutations of the gene are responsible for the double muscling phenotype in several European cattle breeds. The study was conducted to determine the polymorphisms of the bovine myostatin gene at promoter region in Nanyang cattle...

Author(s)
Zhang RunFeng; Chen Hong; Zhang ZhengFeng; Zhang HaiJun; Yan LinJun; Bao Bin
Publisher
Asian Network for Biotechnology in Animal Production and Health, Haidian, China
Citation
Animal Biotechnology Bulletin, 2006, 10, 1, pp 360-362
Abstract

Monoacylglycerol acyltransferase (MGAT3, also known as MOGAT3) catalyzes the synthesis of diacylglycerol (DAG) using 2-monoacylglycerol and fatty acyl coenzyme A. This enzymatic reaction is believed to be an essential and rate-limiting step for the absorption of dietary fat in the small intestine....

Author(s)
Sun JiaJie; Zhang ChunLei; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2012, 55, 1, pp 56-62
Abstract

The aim of this study was to detect mutations of the nuclear factor I/X (Nfix) gene and examine the association of its polymorphisms with growth traits in cattle. Six sequence variants (SVs) including five single-nucleotide mutations and an indel with multiple alleles were detected, among which...

Author(s)
Zhou Yang; Lan XianYong; Xu Yao; Zhang Bao; Li MiJie; Huang YongZhen; Sun JiaJie; Cai HanFang; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2012, 55, 12, pp 845-851

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