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Abstract

Background: Copy number variations (CNVs) are structural variants consisting of large-scale insertions and deletions of genomic fragments. Exploring CNVs and estimating their effects on phenotypes are useful for genome selection but remain challenging in the livestock. Results: We identified 1043...

Author(s)
Liu Mei; Fang LingZhao; Liu ShuLi; Pan, M. G.; Seroussi, E.; Cole, J. B.; Ma Li; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2019, 20, 181, pp (7 March 2019)
Abstract

Background: Copy number variation (CNV) is an important type of genetic variation contributing to phenotypic differences among mammals and may serve as an alternative molecular marker to single nucleotide polymorphism (SNP) for genome-wide association study (GWAS). Recently, GWAS analysis using CNV ...

Author(s)
Zhou Yang; Connor, E. E.; Wiggans, G. R.; Lu YongFang; Tempelman, R. J.; Schroeder, S. G.; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2018, 19, 314, pp (2 May 2018)
Abstract

Viral infections can play direct or indirect roles in the etiology of the bovine mastitis. Mx dynamin-like GTPase 2 (MX2) gene is a main effector of the antiviral innate immune defense mediated by type I interferon (IFN I), which was demonstrated to confer positive antiviral responses to many...

Author(s)
Chen NingBo; Wang FengQiao; Yu NongQi; Gao Yuan; Huang JiePing; Dang RuiHua; Huang YongZhen; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2018, 29, 2, pp 81-89
AbstractFull Text

The primary agent of mastitis is a wide spectrum of bacterial strains; however, viral-related mastitis has also been reported. The MX dynamin-like GTPase 1 (MX1) gene has been demonstrated to confer positive antiviral responses to many viruses, and may be a suitable candidate gene for the study of...

Author(s)
Chen NingBo; Wang FengQiao; Yu NongQi; Gao Yuan; Huang JiePing; Huang YongZhen; Lan XianYon; Lei ChuZhao; Chen Hong; Dang RuiHua
Publisher
Czech Academy of Agricultural Sciences, Prague, Czech Republic
Citation
Czech Journal of Animal Science, 2017, 62, 4, pp 157-167
Abstract

Beef production is an economically important sector of animal husbandry and much attention has been paid on the identification of molecular markers associated with gene expressions and growth traits. The aim of this study was to search for potential effects of a novel copy number variation (CNV)...

Author(s)
Liu Mei; Li Bo; Huang YongZhen; Yang MingJuan; Lan XianYong; Lei ChuZhao; Qu WeiDong; Bai YueYu; Chen Hong
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Livestock Science, 2016, 194, pp 44-50
Abstract

It has been well established that mutations of the solute carrier family 11 A1 (SLC11A1) gene are responsible for susceptibility to a number of intracellular pathogens. Mastitis is the most common and most costly disease of dairy cattle, commonly caused by bacteria. As SLC11A1 protein is involved...

Author(s)
Zhang ChunLei; Wang YanHong; Chen Hong; Gu ChuanWen; Fang XingTang
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Veterinary Immunology and Immunopathology, 2009, 127, 3/4, pp 389-392
Abstract

Genetic polymorphisms of prolactin (PRL) and prolactin receptor (PRLR) genes in Chinese Holstein cattle were detected by PCR-SSCP methods. Polymorphisms were observed in both genes and direct sequencing confirmed the A > G mutation at position 8398 in exon 4 of PRL gene and the A > C mutation at...

Author(s)
Hu XiuCai; LüAiJun; Chen Hong; Gao XueYuan; Xu HaiXia; Zhang ChunLei; Fang XingTang; Lei ChuZhao
Publisher
Garuda Scientific Publications, Izatnagar, India
Citation
Journal of Applied Animal Research, 2009, 36, 2, pp 213-217
Abstract

Genetic variability and genetic relationships were investigated among eight Chinese cattle breeds using 12 microsatellite markers. Three hundred and fifty-two alleles were detected and the average number of alleles per locus ranged from 8.33±1.67 in the Jiaxian breed to 21.33±5.60 in the Qinchuan...

Author(s)
Sun WeiBin; Chen Hong; Lei ChuZhao; Lei XueQin; Zhang YingHan
Publisher
EDP Sciences, Les Ulis, France
Citation
Genetics, Selection, Evolution, 2008, 40, 6, pp 681-692
Abstract

Blood and milk samples were collected from 61 Holstein cows in a farm in Xi'an area, China. Somatic cell count (SCC) and pre-somatic cell score (PreSCC) were recorded and somatic cell score (SCS) was calculated. PCR-RFLP (restriction fragment length polymorphism) was carried out on IGFBP-3, β-lg 5' ...

Author(s)
Zhang RunFeng; Chen Hong; Lei ChuZhao; Fang XingTang; Lan XianYong; Hu ShenRong; Su LiHong
Publisher
China Agricultural University, Beijing, China
Citation
Journal of Agricultural Biotechnology, 2007, 15, 1, pp 179-180
Abstract

In a study, insulin-like growth factor binding protein 3 (IGFBP-3) gene was regarded as candidate gene of partial milk traits in Chinese Holstein. Analysis on 61 Chinese Holstein dairy cows with PROC GLM of SAS, LS Means ANOVA revealed that the effect of IGFBP-3 locus on milk yield, protein...

Author(s)
Zhang RunFeng; Chen Hong; Lei ChuZhao; Hu ShenRong; Su LiHong
Publisher
Guoji Shudian (Institute of Scientific and Technological Information of China, China Publications Centre), Beijing, China
Citation
Chinese Journal of Animal Science, 2006, 42, 3, pp 9-11

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