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Abstract

The identification of copy number variations (CNVs) allow us to explore genomic polymorphisms. In recent years, significant progress in understanding CNVs has been made in studies of human and animals, however, association and expression studies of CNVs are still in the early stage. It was...

Author(s)
Yang MingJuan; Lv JingQiao; Zhang LiangZhi; Li MingXun; Zhou Yang; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2017, 7, 1, pp 46599
Abstract

The aim of this study was to detect mutations of the nuclear factor I/X (Nfix) gene and examine the association of its polymorphisms with growth traits in cattle. Six sequence variants (SVs) including five single-nucleotide mutations and an indel with multiple alleles were detected, among which...

Author(s)
Zhou Yang; Lan XianYong; Xu Yao; Zhang Bao; Li MiJie; Huang YongZhen; Sun JiaJie; Cai HanFang; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2012, 55, 12, pp 845-851
Abstract

The paired box 7 (Pax7) gene encoding for the transcription factor can regulate the conversion of stem cells into myogenic cells and participate in the development and regeneration of skeletal muscle. The aims of this study were to detect variations of the Pax7 gene by DNA pool sequencing and...

Author(s)
Xu Yao; Zhou Yang; Wang Ning; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 1, pp 9-15
Abstract

Background: Copy number variation (CNV) is an important type of genetic variation contributing to phenotypic differences among mammals and may serve as an alternative molecular marker to single nucleotide polymorphism (SNP) for genome-wide association study (GWAS). Recently, GWAS analysis using CNV ...

Author(s)
Zhou Yang; Connor, E. E.; Wiggans, G. R.; Lu YongFang; Tempelman, R. J.; Schroeder, S. G.; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2018, 19, 314, pp (2 May 2018)
Abstract

Flightless-1 (FLII) is essential for early embryogenesis, structural organization of indirect flight muscle and can inhibit adipocyte differentiation. We therefore aimed to identify common variations in FLII gene and to investigate their effects on cattle growth traits. By DNA sequencing and forced ...

Author(s)
Liu Mei; Liu Min; Li Bo; Zhou Yang; Huang YongZhen; Lan XianYong; Qu WeiDong; Qi XingShan; Bai YueYu; Chen Hong
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Molecular and Cellular Probes, 2016, 30, 4, pp 266-272
Abstract

Objective: The study was conducted to detect the genetic diversity and relationship of cattle in south China. Method: The complete mitochondrial control regions of 40 cattle in 8 breeds were sequenced and analyzed. Result: The results showed as follows: 56 variations and 17 haplotypes were...

Author(s)
Zhou Yan; Chen Hong; Jia ShanGang; Lei ChuZhao
Publisher
Northwest A & F University (Natural Science Edition), Yangling, China
Citation
Journal of Northwest A & F University - Natural Science Edition, 2008, 36, 5, pp 7-11
Abstract

Complete mitochondrial D-loop sequences of 140 samples obtained from 15 Chinese local cattle breeds were analyzed. The result showed 67 different haplotypes with 113 polymorphic sites. The haplotype diversity and nucleotide diversity were 0.608-1.000 and 0.002-0.028, respectively, indicating...

Author(s)
Fang XingTang; Zhou Yan; Chen Hong; Cai Xin; Fang NanZhu
Publisher
Science Press, Beijing, China
Citation
Acta Zoologica Sinica, 2007, 53, 5, pp 928-933
Abstract

Paired box 3 (PAX3) belongs to the PAX superfamily of transcription factors and plays essential roles in the embryogenesis and postnatal formation of limb musculature through affecting the survival of muscle progenitor cells. By genetic mapping, PAX3 gene is assigned in the interval of quantitative ...

Author(s)
Xu Yao; Cai HanFang; Zhou Yang; Shi Tao; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Jia YuTang; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 7, pp 4295-4303

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