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Abstract

Background: Copy number variations (CNVs) are a main source of genomic structural variations underlying animal evolution and production traits. Here, with one pure-blooded Angus bull as reference, we describe a genome-wide analysis of CNVs based on comparative genomic hybridization arrays in 29...

Author(s)
Zhang LiangZhi; Jia ShanGang; Yang MingJuan; Xu Yao; Li, C. J.; Sun JiaJie; Huang YongZhen; Lan XianYong; Lei ChuZhao; Zhou Yang; Zhang ChunLei; Zhao Xin; Chen Hong
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2014, 15, 480, pp (17 June 2014)
Abstract

The paired box 7 (Pax7) gene encoding for the transcription factor can regulate the conversion of stem cells into myogenic cells and participate in the development and regeneration of skeletal muscle. The aims of this study were to detect variations of the Pax7 gene by DNA pool sequencing and...

Author(s)
Xu Yao; Zhou Yang; Wang Ning; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 1, pp 9-15
Abstract

As an adaptor protein, apart from potentiating Janus kinase 2 (JAK2) activation and promoting the insulin signaling pathway, Src homology 2 B 2 (SH2B2) indirectly takes part in the regulation of glucose uptake through the c-Cb1/CAP/TC10 pathway, which can in turn affect growth. In this study, we...

Author(s)
Yang MingJuan; Fu JunHui; Lan XianYong; Sun YuJia; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 528, 2, pp 314-319
Abstract

Objective: The purpose of this study is to reveal the genetic variation characteristics of bovine ANGPTL6 gene and find several candidate molecular markers that related to growth traits of Luxi cattle, thus for accumulating some basic information for molecular breeding of Luxi cattle breed. Method: ...

Author(s)
Li AiMin; Ma Yun; Yang DongYing; Lan XianYong; Hu ShenRong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Scientia Agricultura Sinica, Beijing, China
Citation
Scientia Agricultura Sinica, 2012, 45, 11, pp 2306-2314
AbstractFull Text

Fat-inducing transcript (FIT) are endoplasmic reticulum-resident membrane proteins that induce lipid droplet accumulation. It plays a crucial role in the fundamental process of storing fat. In this study, applying the PCR-SSCP and DNA sequencing methods, polymorphism of the FIT gene were detected....

Author(s)
Sun JiaJie; Zhang ChunLei; Fang XingTang; Lei ChuZhao; Lan XianYong; Chen Hong
Publisher
Polish Academy of Sciences, Institute of Genetics and Animal Breeding, Jastrzebiec, Poland
Citation
Animal Science Papers and Reports, 2011, 29, 2, pp 99-107
Abstract

Retinoic acid receptor responder 2 gene (RARRES2) encodes a novel adipokine protein that plays a crucial role in regulating several biological processes, including immune responses, adipocyte differentiation, type 2 diabetes and metabolic syndrome. In this paper, polymorphisms of the bovine RARRES2 ...

Author(s)
Zhang Ya; Zhu JinLong; Wang Chen; Sun JiaJie; Lai XinSheng; Xu Yao; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Yang DonbGying; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2012, 39, 3, pp 2305-2311
Abstract

We investigated the polymorphisms of bovine cocaine- and amphetamine-regulated transcripts (CART). The coding and regulating regions of CART were screened in 7 cattle breeds by the single-stranded conformation polymorphism (SSCP) technique. The four loci (C1, C2, C3 and C4) studied were all...

Author(s)
Zhang ChunLei; Chen Hong; Wang YanHong; Lan XianYong; Lei ChuZhao; Fang XingTang
Publisher
Indian Academy of Sciences, Bangalore, India
Citation
Journal of Biosciences, 2008, 33, 3, pp 365-370
Abstract

The PCR-SSCP technique was used to analyse the polymorphisms of the 10th exon of the GHR gene in Qinchuan cattle. The PCR products demonstrated the polymorphisms in Qinchuan cattle. Moreover, the population showed a Hardy-Weinberg equilibrium. There were 3 allele genes (A, B and C) in this locus,...

Author(s)
Zhao GaoFeng; Chen Hong; Lei ChuZhao; Zhang ChunLei; Zhang Li; Lan XianYong; Fang XingTang; Kang XiangTao
Publisher
Editorial Office of Hereditas (Beijing), Beijing, China
Citation
Hereditas (Beijing), 2007, 29, 3, pp 319-323

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