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Abstract

I-mfa (inhibitor of the MyoD family a) is a transcription modulator that binds to MyoD family members and inhibits their transcriptional activities. It is highly expressed in the sclerotome and plays an important role in the patterning of the somite early in development. In this study, the...

Author(s)
Huang YongZhen; Li JingJing; Zhang ChunLei; Fang XingTang; Lan XianYong; Qi XingLei; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2016, 27, 4, pp 278-286
Abstract

Copy number variations (CNVs) have been recently recognized as another important genetic variability complementary to single nucleotide polymorphisms (SNPs). Compelling evidence has indicated that CNVs are responsible for phenotypic traits by changing the copy numbers of functional genes. Myosin...

Author(s)
Xu Yao; Shi Tao; Cai HanFang; Zhou Yang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Qi XingLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 535, 2, pp 106-111
Abstract

NPC1 gene is an important gene closely related to the Niemann-Pick type C (NPC). Mutations in the NPC1 gene tend to cause Niemann-Pick type C, a lysosomal storage disorder. Previous studies have shown that NPC1 protein plays an important role in subcellular lipid transport, homeostasis, platelet...

Author(s)
Dang YongLong; Li MingXun; Yang MingJuan; Cao XiuKai; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Lin Qing; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 540, 2, pp 153-160
Abstract

Copy number variations (CNVs) recently have been recognized as an important source of genetic variability. Compelling evidence has indicated that CNVs are responsible for phenotypic traits by altering the copy numbers of functional genes. The molecule interacting with CasL-like protein 2 (MICAL-L2) ...

Author(s)
Xu Yao; Zhang LiangZhi; Shi Tao; Zhou Yang; Cai HanFang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
Springer, New York, USA
Citation
Mammalian Genome, 2013, 24, 11/12, pp 508-516
Abstract

The paired box 7 (Pax7) gene encoding for the transcription factor can regulate the conversion of stem cells into myogenic cells and participate in the development and regeneration of skeletal muscle. The aims of this study were to detect variations of the Pax7 gene by DNA pool sequencing and...

Author(s)
Xu Yao; Zhou Yang; Wang Ning; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 1, pp 9-15
Abstract

Muscle growth is a complex phenomenon regulated by many factors, whereby net growth results from the combined action of synthesis and turnover. Insulin-like growth factor 2 (IGF2) is a fetal growth and differentiation factor that plays an important role in muscle growth and in myoblast...

Author(s)
Huang YongZhen; Zhan ZhaoYang; Sun YuJia; Wang Jing; Li MingXun; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 6, pp 327-334
Abstract

As an adaptor protein, apart from potentiating Janus kinase 2 (JAK2) activation and promoting the insulin signaling pathway, Src homology 2 B 2 (SH2B2) indirectly takes part in the regulation of glucose uptake through the c-Cb1/CAP/TC10 pathway, which can in turn affect growth. In this study, we...

Author(s)
Yang MingJuan; Fu JunHui; Lan XianYong; Sun YuJia; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 528, 2, pp 314-319
Abstract

Objective: The purpose of this study is to reveal the genetic variation characteristics of bovine ANGPTL6 gene and find several candidate molecular markers that related to growth traits of Luxi cattle, thus for accumulating some basic information for molecular breeding of Luxi cattle breed. Method: ...

Author(s)
Li AiMin; Ma Yun; Yang DongYing; Lan XianYong; Hu ShenRong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Scientia Agricultura Sinica, Beijing, China
Citation
Scientia Agricultura Sinica, 2012, 45, 11, pp 2306-2314
Abstract

Neuropeptide Y (NPY) is one of the most potent orexigenic factors that is implicated in the control of feeding behavior and energy homeostasis. Four Chinese indigenous cattle breeds (n=338) were used to detect single nucleotide polymorphisms (SNPs) in the coding regions with their intron-exon...

Author(s)
Zhang Li; Zhang AiLing; Zhang LiangZhi; Zhang Qin; Zhang ChunLei; Lan XianYong; Chen Hong
Publisher
Elsevier, Amsterdam, Netherlands
Citation
General and Comparative Endocrinology, 2011, 170, 1, pp 189-192
Abstract

PCR-SSCP and DNA sequencing methods were employed to screen the genetic variation of vascular endothelial growth factor (VEGF) gene in 675 individuals belonging to three Chinese indigenous cattle breeds including Qinchuan (QC), Jiaxian Red (JX) and Nanyang (NY) breed. Three new single nucleotide...

Author(s)
Pang YongHong; Lei ChuZhao; Zhang ChunLei; Lan XianYong; Yue WangPing; Gu ChuanWen; Chen DanXia; Wang JuQiang; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2011, 38, 5, pp 3219-3225

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