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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

NPC1 gene is an important gene closely related to the Niemann-Pick type C (NPC). Mutations in the NPC1 gene tend to cause Niemann-Pick type C, a lysosomal storage disorder. Previous studies have shown that NPC1 protein plays an important role in subcellular lipid transport, homeostasis, platelet...

Author(s)
Dang YongLong; Li MingXun; Yang MingJuan; Cao XiuKai; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Lin Qing; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 540, 2, pp 153-160
Abstract

Muscle growth is a complex phenomenon regulated by many factors, whereby net growth results from the combined action of synthesis and turnover. Insulin-like growth factor 2 (IGF2) is a fetal growth and differentiation factor that plays an important role in muscle growth and in myoblast...

Author(s)
Huang YongZhen; Zhan ZhaoYang; Sun YuJia; Wang Jing; Li MingXun; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2013, 56, 6, pp 327-334
Abstract

Patatin-like phospholipase domain-containing protein 3 (PNPLA3), a member of the patatin like phospholipase domain-containing (PNPLA) family, plays an important role in energy balance, fat metabolism regulation, glucose metabolism and fatty liver disease. Tetra-primer amplification refractory...

Author(s)
Wang ZiNian; Cai HanFang; Li MingXun; Cao XiuKai; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2016, 575, 2 Part 1, pp 191-198
Abstract

Hepatocyte nuclear factor-4α (HNF-4α), a member of the hepatocyte nuclear factor family, plays an important role in regulating the expression of genes involved in the development, differentiation and normal function of liver and pancreatic β cells, as well as the maintenance of glucose homeostasis. ...

Author(s)
Wang ZiNian; Li MiJie; Lan XianYong; Li MingXun; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 546, 2, pp 206-213

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