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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

Hepatocyte nuclear factor-4α (HNF-4α), a member of the hepatocyte nuclear factor family, plays an important role in regulating the expression of genes involved in the development, differentiation and normal function of liver and pancreatic β cells, as well as the maintenance of glucose homeostasis. ...

Author(s)
Wang ZiNian; Li MiJie; Lan XianYong; Li MingXun; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 546, 2, pp 206-213
Abstract

The peroxisome proliferator-activated receptor gamma coactivator-1 alpha protein, encoded by the PPARGC1A gene, is a metabolic switch, which transcriptionally activates a complex pathway of mitochondrial biogenesis, lipid and glucose metabolism. Three SNPs (exon 3 c.396G>A, intron 9 c.1892+19C>T...

Author(s)
Li MiJie; Liu Mei; Liu Dong; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 1, pp 39-44