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Abstract

Genetic polymorphism has great influences on the improvement of cattle traits. The polymorphism of the same gene family will greatly change the growth traits of cattle, such as the pleomorphic adenoma gene (PLAG) family. Many studies have shown that the PLAG family proteins are the transcription...

Author(s)
Zhong JiaLin; Xu JiaWei; Wang Jian; Wen YiFan; Niu Hui; Zheng Li; He Hua; Peng Kun; He Pan; Shi ShuYue; Huang YinQi; Lei ChuZhao; Dang RuiHua; Lan XianYong; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 689, pp 166-171
Abstract

We report genome characterization of three native Chinese cattle breeds discovering ∼34.3 M SNPs and ∼3.8 M InDels using whole genome resequencing. On average, 10.4 M SNPs were shared amongst the three cattle breeds, whereas, 3.0 M, 4.9 M and 5.8 M were specific to LQ, WN and WS breeds,...

Author(s)
Zhang FengWei; Qu KaiXing; Chen NingBo; Hanif, Q.; Jia YuTang; Huang YongZhen; Dang RuiHua; Zhang JiCai; Lan XianYong; Chen Hong; Huang BiZhi; Lei ChuZhao
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2019, 9, 9, pp 596
Abstract

Polymorphisms in the prion protein gene (PRNP) have been linked with the occurrence of transmissible spongiform encephalopathies and the expression of some phenotypic traits in healthy animals including cattle. The aim of this study was to verify the 23-bp insertion/deletion (indel) within promoter ...

Author(s)
Yang Qing; Zhang SiHuan; Liu LiangLiang; Lei ChuZhao; Qi XingLei; Lin FengPeng; Qu WeiDong; Qi XingShan; Liu JiMing; Wang RongMin; Chen Hong; Lan XianYong
Publisher
Taylor & Francis, Abingdon, UK
Citation
Journal of Applied Animal Research, 2018, 46, 1, pp 505-511
Abstract

Identification of polymorphisms associated with economic traits is important for successful marker-assisted selection in cattle breeding. The family of mammalian sirtuin regulates many biological functions, such as life span extension and energy metabolism. SIRT2, a most abundant sirtuin in...

Author(s)
Sun XiaoMei; Li MingXun; Hao Dan; Hua LiuShuai; Lan XianYong; Lei ChuZhao; Hu ShenRong; Qi XingLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2015, 42, 3, pp 729-736
Abstract

Myocyte enhancer factor 2C (MEF2C) gene was annotated for its potential phenotypic effects on bovine stature including body dimensions and body weight. The aim of this study was the analysis of MEF2C as a candidate for bovine stature. Four SNPs including two novel SNPs were identified and the...

Author(s)
Cao XiuKai; Zhan ZhaoYang; Huang YongZhen; Lan XianYong; Lei ChuZhao; Qi XingLei; Chen Hong
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Livestock Science, 2016, 185, pp 106-109
Abstract

To determine the Y chromosome genetic diversity and paternal origin of Chinese cattle, 369 bulls from 17 Chinese native cattle breeds and 30 bulls from Holstein and four bulls from Burma were analyzed using a recently discovered USP9Y marker that could distinguish between taurine and indicine ...

Author(s)
Li Ran; Xie WenMei; Chang ZhenHua; Wang ShaoQiang; Dang RuiHua; Lan XianYong; Chen Hong; Lei ChuZhao
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2013, 40, 12, pp 6633-6636
Abstract

Background: Copy number variations (CNVs) are a main source of genomic structural variations underlying animal evolution and production traits. Here, with one pure-blooded Angus bull as reference, we describe a genome-wide analysis of CNVs based on comparative genomic hybridization arrays in 29...

Author(s)
Zhang LiangZhi; Jia ShanGang; Yang MingJuan; Xu Yao; Li, C. J.; Sun JiaJie; Huang YongZhen; Lan XianYong; Lei ChuZhao; Zhou Yang; Zhang ChunLei; Zhao Xin; Chen Hong
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2014, 15, 480, pp (17 June 2014)
Abstract

Copy number variations (CNVs) have been recently recognized as another important genetic variability complementary to single nucleotide polymorphisms (SNPs). Compelling evidence has indicated that CNVs are responsible for phenotypic traits by changing the copy numbers of functional genes. Myosin...

Author(s)
Xu Yao; Shi Tao; Cai HanFang; Zhou Yang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Qi XingLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 535, 2, pp 106-111
Abstract

Bone morphogenetic proteins (BMPs) are peptide growth factors belonging to the transforming growth factor-beta (TGF-β) superfamily, and some members of the BMP family support white adipocyte differentiation. In this study, we focused on the BMP7 which singularly promotes the differentiation of...

Author(s)
Huang YongZhen; Wang XinLei; He Hua; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 532, 2, pp 281-287
Abstract

Tetra-primer amplification refractory mutation system PCR (T-ARMS-PCR) offers fast detection and extreme simplicity at a negligible cost for SNP genotyping. SIRT2, the family member (sirtuins, SIRT1-7) with the greatest homology to the silent information regulator 2 (Sir2), is the most abundantly...

Author(s)
Li MingXun; Sun XiaoMei; Jiang Jing; Sun YuJia; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Royal Society of Chemistry, Cambridge, UK
Citation
Analytical Methods, 2014, 6, 6, pp 1835-1840

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