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Abstract

Adipocyte differentiation-associated long noncoding RNA (ADNCR) is a newly discovered lncRNA. It plays function by targeting miR-204 to significantly regulates the expression of the target SIRT1 gene in preadipocytes both at the level of mRNA and protein, thereby inhibiting adipogenesis. The...

Author(s)
Jin YunYun; Yang Qing; Zhang Meng; Zhang SiHuan; Cai HanFang; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 2, pp 159-165
Abstract

Genetic polymorphism has great influences on the improvement of cattle traits. The polymorphism of the same gene family will greatly change the growth traits of cattle, such as the pleomorphic adenoma gene (PLAG) family. Many studies have shown that the PLAG family proteins are the transcription...

Author(s)
Zhong JiaLin; Xu JiaWei; Wang Jian; Wen YiFan; Niu Hui; Zheng Li; He Hua; Peng Kun; He Pan; Shi ShuYue; Huang YinQi; Lei ChuZhao; Dang RuiHua; Lan XianYong; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 689, pp 166-171
Abstract

We report genome characterization of three native Chinese cattle breeds discovering ∼34.3 M SNPs and ∼3.8 M InDels using whole genome resequencing. On average, 10.4 M SNPs were shared amongst the three cattle breeds, whereas, 3.0 M, 4.9 M and 5.8 M were specific to LQ, WN and WS breeds,...

Author(s)
Zhang FengWei; Qu KaiXing; Chen NingBo; Hanif, Q.; Jia YuTang; Huang YongZhen; Dang RuiHua; Zhang JiCai; Lan XianYong; Chen Hong; Huang BiZhi; Lei ChuZhao
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2019, 9, 9, pp 596
Abstract

The potassium inwardly rectifying channel, subfamily J, member 12 (KCNJ12) gene is a promising candidate for economic traits because of its crucial roles in myoblast development. Here, a missense mutation (Cys > Arg) was first detected to be located in exon 3 of KCNJ12 from three Chinese cattle...

Author(s)
Cheng Jie; Peng WenWen; Cao XiuKai; Huang YongZhen; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2019, 9, 5, pp 273
Abstract

Cattle domestication and the complex histories of East Asian cattle breeds warrant further investigation. Through analysing the genomes of 49 modern breeds and eight East Asian ancient samples, worldwide cattle are consistently classified into five continental groups based on Y-chromosome...

Author(s)
Chen NingBo; Cai YuDong; Chen QiuMing; Li Ran; Wang Kun; Huang YongZhen; Hu SongMei; Huang ShiSheng; Zhang HuCai; Zheng ZhuQing; Song WeiNing; Ma ZhiJie; Ma Yun; Dang RuiHua; Zhang ZiJing; Xu Lei; Jia YuTang; Liu ShanZhai; Yue XiangPeng; Deng WeiDong; Zhang XiaoMing; Sun ZhouYong; Lan XianYong; Han JianLin; Chen Hong; Bradley, D. G. (et al)
Publisher
Nature Publishing Group, London, UK
Citation
Nature Communications, 2018, 9, 6, pp 2337
Abstract

Our previous work reported a relationship between FOXO1 mutations and growth of Qinchuan (QC) cattle. Here, we performed differential expression analysis of FOXO1 and its association analysis with growth traits in QC cattle. First, we measured the expression of the FOXO1 gene in nine tissues during ...

Author(s)
Sun YuJia; Liu KunPeng; Huang YongZhen; Lan XianYong; Chen Hong
Publisher
Science China Press, co-published with Springer, Berlin, Germany
Citation
Science China Life Sciences, 2018, 61, 7, pp 826-835
Abstract

Angiopoietin-like protein 6, which is encoded by ANGPTL6 gene (also known as angiopoietin growth factor, AGF), has been extensively characterized with regard to its proposed functions as angiogenesis and energy metabolism. The present results showed the occurrence of alternative splicing by intron...

Author(s)
Wu JiYao; Li AiMin; Cai HanFang; Zhang ChenGe; Lei ChuZhao; Lan XianYong; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 709, pp 17-24
Abstract

NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair regeneration of skeletal muscles. However, similar research on the bovine ...

Author(s)
Liu Mei; Zhang ChenGe; Lai XinSheng; Xue Jing; Lan XianYong; Lei ChuZhao; Jia YuTang; Chen Hong
Publisher
Springer Berlin, Heidelberg, Germany
Citation
Journal of Applied Genetics, 2017, 58, 2, pp 241-247
Abstract

WNT-β-Catenin-TCF pathway is involved in carcinogenesis and foetal development. As a member of the WNT gene family, Wnt8A encodes secreted signalling proteins and responds to many biological processes. However, similar research on the effects of genetic variations of Wnt8A gene on growth traits is...

Author(s)
Huang YongZhen; Zou Yong; Lin Qing; He Hua; Zheng Li; Zhang ZiJing; Dang YongLong; Lei ChuZhao; Lan XianYong; Qi XingShan; Chen Hong
Publisher
Indian Academy of Sciences, Bangalore, India
Citation
Journal of Genetics, 2017, 96, 4, pp 535-544
Abstract

The aim of this study was to examine the association of cofilin2 (CFL2) gene polymorphisms with growth traits in Chinese Qinchuan cattle. Three single nucleotide polymorphisms (SNPs) were identified in the bovine CFL2 gene using DNA sequencing and (forced) PCR-RFLP methods. These polymorphisms...

Author(s)
Sun YuJia; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2015, 563, 2, pp 136-141

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