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Abstract

Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains a persistent problem for cattle industries in endemic countries. The frequency, quality, and performance of tests, and the presence of wildlife reservoirs, have been identified as impediments to eradication. Recently, exposure to...

Author(s)
Byrne, A. W.; McBride, S.; Graham, J.; Lahuerta-Marin, A.; McNair, J.; Skuce, R. A.; McDowell, S. W.
Publisher
Wiley, Berlin, Germany
Citation
Transboundary and Emerging Diseases, 2019, 66, 2, pp 785-796
Abstract

Accuracy of new or alternative diagnostic tests is typically estimated in relation to a well-standardized reference test referred to as a gold standard. However, for bovine tuberculosis (bTB), a chronic disease of cattle, affecting animal and public health, no reliable gold standard is available....

Author(s)
Picasso-Risso, C.; Perez, A.; Gil, A.; Nunez, A.; Salaberry, X.; Suanes, A.; Alvarez, J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2019, 6, August, pp 261
Abstract

Co-infection of tuberculosis (TB) and helminths is recognized as a significant problem in regions where such pathogens are endemic and chronic cases exist. Co-infection can modulate the immune system leading to interference with diagnostic tests, increased pathological impacts and pathogen...

Author(s)
Byrne, A. W.; Graham, J.; McConville, J.; Milne, G.; Guelbenzu-Gonzalo, M.; McDowell, S.
Publisher
Wiley, Berlin, Germany
Citation
Transboundary and Emerging Diseases, 2019, 66, 4, pp 1727-1736
Abstract

Bovine Tuberculosis (bTB) in cattle is a global health problem and eradication of the disease requires accurate estimates of diagnostic test performance to optimize their efficiency. The objective of this study was, through statistical meta-analyses, to obtain estimates of sensitivity (Se) and...

Author(s)
Nuñez-Garcia, J.; Downs, S. H.; Parry, J. E.; Abernethy, D. A.; Broughan, J. M.; Cameron, A. R.; Cook, A. J.; Rua-Domenech, R. de la; Goodchild, A. V.; Gunn, J.; More, S. J.; Rhodes, S.; Rolfe, S.; Sharp, M.; Upton, P. A.; Vordermeier, H. M.; Watson, E.; Welsh, M.; Whelan, A. O.; Woolliams, J. A.; Clifton-Hadley, R. S.; Greiner, M.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2018, 153, pp 94-107
Abstract

In Spain, the national bovine tuberculosis (bTB) eradication program is based on yearly skin testing of every ≥6 weeks old animal using the single or comparative tuberculin test and parallel use of the interferon-gamma (IFN-γ) assay as an ancillary diagnostic test in infected herds. There are...

Author(s)
Cruz, M. L. de la; Branscum, A. J.; Nacar, J.; Pages, E.; Pozo, P.; Perez, A.; Grau, A.; Saez, J. L.; Juan, L. de; Diaz, R.; Minguez, O.; Alvarez, J.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Veterinary Science, 2018, 5, September, pp 229
Abstract

In Spain, despite years of efforts to eradicate bovine tuberculosis (bTB), the disease is still endemic, with some areas of high prevalence. In this context, the surveillance and control plans may need to be re-evaluated, and understanding the dynamics of bTB spread within Spanish herds may help to ...

Author(s)
Ciaravino, G.; García-Saenz, A.; Cabras, S.; Allepuz, A.; Casal, J.; García-Bocanegra, I.; Koeijer, A. de; Gubbins, S.; Sáez, J. L.; Cano-Terriza, D.; Napp, S.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Epidemics, 2018, 23, pp 110-120
Abstract

The gamma-interferon assay (IFNγ) is often used as an ancillary diagnostic test alongside the tuberculin skin test in order to detect Mycobacterium bovis infected cattle. The performance of the IFNγ test has been evaluated in many countries worldwide and wider usage as a disease surveillance tool...

Author(s)
Gormley, E.; Doyle, M.; Duignan, A.; Good, M.; More, S. J.; Clegg, T. A.
Publisher
BioMed Central Ltd, London, UK
Citation
Veterinary Research, 2013, 44, 117, pp (5 December 2013)
Abstract

An observational case-control study was conducted to investigate risk factors for confirmed bovine tuberculosis (bTB) infection in cattle reacting positively to the single intradermal comparative cervical test (SICCT) in Northern Ireland in the years 1998, 2002 and 2006. Macroscopic lesions were...

Author(s)
O'Hagan, M. J. H.; Courcier, E. A.; Drewe, J. A.; Gordon, A. W.; McNair, J.; Abernethy, D. A.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Preventive Veterinary Medicine, 2015, 120, 3/4, pp 283-290
Abstract

Test-and-slaughter strategies have been the basis of bovine tuberculosis (BT) eradication programs worldwide; however, eradication efforts have not succeeded in certain regions, and imperfect sensitivity and specificity of applied diagnostic techniques have been deemed as one of the possible causes ...

Author(s)
Álvarez, J.; Perez, A.; Bezos, J.; Marqués, S.; Grau, A.; Saez, J. L.; Mínguez, O.; Juan, L. de; Domínguez, L.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Microbiology, 2012, 155, 1, pp 38-43
Abstract

Considerable effort has been devoted to improving the existing diagnostic tests for bovine tuberculosis (single intradermal comparative tuberculin test [SICTT] and γ-interferon assay [γ-IFN]) and to develop new tests. Previously, the diagnostic characteristics (sensitivity, specificity) have been...

Author(s)
Clegg, T. A.; Duignan, A.; Whelan, C.; Gormley, E.; Good, M.; Clarke, J.; Toft, N.; More, S. J.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Microbiology, 2011, 151, 1/2, pp 68-76

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