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Abstract

Bacteria of the genus Brucella infect a range of vertebrates causing a worldwide extended zoonosis. The best-characterized brucellae infect domestic livestock, behaving as stealthy facultative intracellular parasites. This stealthiness depends on envelope molecules with reduced pathogen-associated...

Author(s)
Zúñiga-Ripa, A.; Barbier, T.; Lázaro-Antón, L.; Miguel, M. J. de; Conde-Álvarez, R.; Muñoz, P. M.; Letesson, J. J.; Iriarte, M.; Moriyón, I.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Microbiology, 2018, 9, April, pp 641
Abstract

The aim of this study was to compare the genetic diversity of the single copy Bv80 gene sequences of Babesia bovis in populations of attenuated and virulent parasites. PCR/RT-PCR followed by cloning and sequence analyses of 4 attenuated and 4 virulent strains were performed. Multiple fragments in...

Author(s)
Mazuz, M. L.; Molad, T.; Fish, L.; Leibovitz, B.; Wolkomirsky, R.; Fleiderovitz, L.; Shkap, V.
Publisher
Cambridge University Press, Cambridge, UK
Citation
Parasitology, 2012, 139, 3, pp 317-323
Abstract

To assess transmissibility of attenuated Babesia bigemina (BIS) and Babesia bovis (BOR) strains by Rhipicephalus microplus (R. microplus), 12 steers from a tick-free area were divided in four groups and infested at different intervals with R. microplus larvae. One animal from each group was...

Author(s)
Rojas Ramírez, E. E.; Mosqueda Gualito, J. J.; Álvarez Martínez, J. A.; Hernández Ortíz, R.; Ramos Aragón, J. A.; Rojas Martínez, C.; Vega y Murguia, C. A.; Figueroa Millán, J. V.
Publisher
Instituto Nacional de Investigaciones Forestales, Agrícolas y Pecuarias (INIFAP), Mexico City, Mexico
Citation
Revista Mexicana de Ciencias Pecuarias, 2011, 2, 3, pp 267-281
Abstract

Nuclear and nuclear-related technologies have played an important role in animal health, particularly in relation to disease diagnosis and characterization of pathogenic organisms. This review focuses primarily on how and where nuclear technologies, both non-isotopic and isotopic methods, have made ...

Author(s)
Viljoen, G. J.; Luckins, A. G.
Publisher
Springer, Amsterdam, Netherlands
Citation
Tropical Animal Health and Production, 2012, 44, 7, pp 1341-1366
Abstract

Background: Virulence acquisition and loss is a dynamic adaptation of pathogens to thrive in changing milieus. We investigated the mechanisms of virulence loss at the whole genome level using Babesia bovis as a model Apicomplexan in which genetically related attenuated parasites can be reliably...

Author(s)
Lau, A. O. T.; Kalyanaraman, A.; Echaide, I.; Palmer, G. H.; Bock, R.; Pedroni, M. J.; Rameshkumar, M.; Ferreira, M. B.; Fletcher, T. I.; McElwain, T. F.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2011, 12, 410, pp (12 August 2011)
Abstract

The objectives of this study were: (1) to identify the types of host cells that the sporozoites of T. annulata infect in cattle; (2) to determine whether virulent schizont-infected cell lines differed phenotypically from avirulent cell lines; and (3) to establish wether attenuation in vitro was...

Author(s)
Preston, P. M.; Jackson, L. A.; Sutherland, I. A.; Brown, D. J.; Schofield, J.; Bird, T.; Sanderson, A.; Brown, C. G. D.
Publisher
Academic Press, Orlando, USA
Citation
Experimental Parasitology, 2001, 98, 4, pp 188-205
Abstract

Mediterranean theileriosis is widely distributed throughout southern Spain, where it causes economic losses of considerable importance. In recent studies on 221 fighting bulls from 29 locations of different provinces, mainly in southern Spain, the seroprevalence was 75.1% by IFAT. Studies on beef...

Author(s)
Viseras, J.; García-Fernández, P.
Publisher
Lombardo Editore, Roma, Italy
Citation
Parassitologia (Roma), 1999, 41, Supplement 1, pp 111-115
Abstract

Author(s)
Adamson, R.; Hall, R.
Publisher
Kluwer Academic Publishers, Norwell, USA
Citation
Theileria, 2002, pp 55-67
Abstract

Long-term culture of Theileria annulata is known to result in a reduction in the activity of the host matrix metalloproteinases that play an important role in the pathogenesis of theileriosis. In this study parasites from long-term cultures were used to infect cattle; it was found when infected...

Author(s)
Adamson, R. E.; Ilhan, T.; Wilkie, G. F.; Preston, P. M.; Brown, C. G. D.; Hall, F. R.
Citation
Experimental Parasitology, 2000, 94, 1, pp 45-47
Abstract

In order to investigate how Theileria annulata vaccine cell lines become attenuated, 6 lines from Turkey, India and Tunisia were cultured in vitro for long enough for attenuation to occur. Attenuation is known to be accompanied by a reduction in host matrix metalloproteinases (MMP) activity,...

Author(s)
Hall, R.; Ilhan, T.; Kirvar, E.; Wilkie, G.; Preston, P. M.; Darghouth, M.; Somerville, R.; Adamson, R.
Citation
Tropical Medicine and International Health, 1999, 4, 9, pp A78-A84

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