Cowpox virus (CPXV) is a zoonotic orthopoxvirus (OPV) that infects a wide range of mammals. CPXV-specific DNA and antibodies were detected in different vole species, such as common voles (Microtus arvalis) and bank voles (Myodes glareolus). Therefore, voles are the putative main reservoir host of...

Viruses must be able to resist host innate responses, especially the type I interferon (IFN) response. They do so by preventing the induction or activity of IFN and/or by resisting the antiviral effectors that it induces. Poxviruses are no exception, with many mechanisms identified whereby...

Buffalopox occurs either as a localized (limited to the teats and udder) or a generalized disease. The former was more common. On the CAM the virus caused either a large, white, opaque lesion or a greyish white lesion without central necrosis. The virus caused agglutination of fowl, rabbit and g...

Vaccinia virus caused pock formation when inoculated into the feather follicles of fowls; cow pox virus did not. The test took 3-4 days.-R.M.

Lesions similar to skin pocks were present in the mucosa of the proventriculus of four chickens with fowl pox. Pox virus was isolated on chorio-allantoic membrane of embryonated eggs. V. also records an outbreak of cow pox in Mozambique and vario-liform exanthema in pigs in Mozambique on pages...

The techniques used included complement fixation, gel diffusion and ring precipitation, haemagglutinin inhibition, pock and plaque neutralization, and staining with fluorescein-coupled antibody. Close relationships between vaccinia, cow pox, rabbit pox, and ectromelia, and between myxoma and...

The Dutch rabbit pox or rabbit plague virus isolated by Jansen [V.B. 14, 1735] immunized guineapigs against infection with vaccinia 38 days later, but it protected only one of 8 from cow pox infection. Vaccinia virus protected guineapigs from rabbit pox, but only 2 of 12 were protected from cow...

The c.f. test has provided considerable information on the antigenic composition of vaccinia-variola viruses. The test has also been applied in the demonstration of viral antigen in pus from cases of smallpox and in the detection of antibody in the sera of survivors and in sera of vaccinated...