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Abstract

In this study, we isolated and analysed a small heat shock protein (HSP) of Ostertagia ostertagi (Oo-HSP18). Oo-hsp18 is encoded by a single-copy gene and the full-length cDNA represents an 18-kDa protein. The expression of Oo-hsp18 is highly stage specific and restricted to the adult stage. The...

Author(s)
Vercauteren, I.; Maere, V. de; Vercruysse, J.; Stevens, M.; Gevaert, K.; Claerebout, E.
Publisher
American Society of Parasitologists, Lawrence, USA
Citation
Journal of Parasitology, 2006, 92, 6, pp 1244-1250
Abstract

In this study, we describe the molecular analysis of zinc-metalloproteases from the abomasal nematode Ostertagia ostertagi which were exclusively recognized by local antibodies of immune cattle. Full-length or partial coding sequences of 4 different zinc-metalloprotease cDNAs of Ostertagia (met-1,...

Author(s)
Maere, V. de; Vercauteren, I.; Geldhof, P.; Gevaert, K.; Vercruysse, J.; Claerebout, E.
Publisher
Cambridge University Press, Cambridge, UK
Citation
Parasitology, 2005, 130, 1, pp 89-98
Abstract

The identification of protective helminth antigens remains the most important challenge in the development of parasitic vaccines. To identify protective antigens of Ostertagia ostertagi, an important abomasal parasite of cattle, parasite-specific local antibodies from the abomasal mucus and from...

Author(s)
Maere, V. de; Vercauteren, I.; Saverwyns, H.; Claerebout, E.; Berx, G.; Vercruysse, J.
Publisher
Cambridge University Press, Cambridge, UK
Citation
Parasitology, 2002, 125, 4, pp 383-391
Abstract

RNA interference (RNAi) on parasitic nematodes has been described as successful and useful for the identification of novel drug and vaccine candidates. In this study we have evaluated this technology on the cattle parasite Ostertagia ostertagi. Eight different genes were targeted in L1 and L3 O....

Author(s)
Visser, A.; Geldhof, P.; Maere, V. de; Knox, D. P.; Vercruysse, J.; Claerebout, E.
Publisher
Cambridge University Press, Cambridge, UK
Citation
Parasitology, 2006, 133, 6, pp 777-783
Abstract

Protease inhibitors are thought to protect intestinal parasitic nematodes from their hostile proteolytic environment. In a previous study, screening of Ostertagia ostertagi cDNA libraries with local antibody probes of the abomasal lymph nodes and mucus revealed a (28 kDa) aspartyl protease...

Author(s)
Maere, V. de; Vercauteren, I.; Gevaert, K.; Vercruysse, J.; Claerebout, E.
Publisher
Elsevier, Oxford, UK
Citation
Molecular and Biochemical Parasitology, 2005, 141, 1, pp 81-88

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