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Abstract

Antimicrobial resistant determinants (ARDs) can be transmitted from livestock systems through meat products or environmental effluents. The public health risk posed by these two routes is not well understood, particularly in non-pathogenic bacteria. We collected pooled samples from 8 groups of 1741 ...

Author(s)
Noyes, N. R.; Yang Xiang; Linke, L. M.; Magnuson, R. J.; Dettenwanger, A.; Cook, S.; Geornaras, I.; Woerner, D. E.; Gow, S. P.; McAllister, T. A.; Yang Hua; Ruiz, J.; Jones, K. L.; Boucher, C. A.; Morley, P. S.; Belk, K. E.
Publisher
eLife Sciences Publications Ltd, Cambridge, UK
Citation
eLife, 2016, 5, 13195, pp e13195
Abstract

The objective was to examine effects of treating commercial beef feedlot cattle with therapeutic doses of tulathromycin, a macrolide antimicrobial drug, on changes in the fecal resistome and microbiome using shotgun metagenomic sequencing. Two pens of cattle were used, with all cattle in one pen...

Author(s)
Doster, E.; Rovira, P.; Noyes, N. R.; Burgess, B. A.; Yang Xiang; Weinroth, M. D.; Lakin, S. M.; Dean, C. J.; Linke, L.; Magnuson, R.; Jones, K. I.; Boucher, C.; Ruiz, J.; Belk, K. E.; Morley, P. S.
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Microbiology, 2018, 9, July, pp 1715
Abstract

Treatment of food-producing animals with antimicrobial drugs (AMD) is controversial because of concerns regarding promotion of antimicrobial resistance (AMR). To investigate this concern, resistance genes in metagenomic bovine fecal samples during a clinical trial were analyzed to assess the...

Author(s)
Weinroth, M. D.; Scott, H. M.; Norby, B.; Loneragan, G. H.; Noyes, N. R.; Rovira, P.; Doster, E.; Yang Xiang; Woerner, D. R.; Morley, P. S.; Belk, K. E.
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Applied and Environmental Microbiology, 2018, 84, 13, pp e00610-18
Abstract

It has been proposed that livestock production effluents such as wastewater, airborne dust and manure increase the density of antimicrobial resistant bacteria and genes in the environment. The public health risk posed by this proposed outcome has been difficult to quantify using traditional...

Author(s)
Noyes, N. R.; Yang Xiang; Linke, L. M.; Magnuson, R. J.; Cook, S. R.; Rahat Zaheer; Yang Hua; Woerner, D. R.; Geornaras, I.; McArt, J. A.; Gow, S. P.; Ruiz, J.; Jones, K. L.; Boucher, C. A.; McAllister, T. A.; Belk, K. E.; Morley, P. S.
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2016, 6, 1, pp 24645
Abstract

Background: Infection control is critical to providing high-quality patient care. Many veterinary teaching hospitals (VTHs) utilize footbaths or footmats at entrances and key control points throughout the facility to decrease trafficking of pathogenic microorganism on contaminated footwear....

Author(s)
Hornig, K. J.; Burgess, B. A.; Saklou, N. T.; Johnson, V.; Malmlov, A.; Metre, D. C. van; Morley, P. S.; Byers, S. R.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2016, 30, 6, pp 1882-1886
Abstract

The use of antibiotics in livestock production in North America and possible association with elevated abundance of detectable antimicrobial resistance genes (ARG) is a growing concern. Real-time, quantitative PCR (RT-qPCR) was used to determine the relative abundance and diversity of ARG in fecal...

Author(s)
Beukers, A. G.; Zaheer, R.; Cook, S. R.; Chaves, A. V.; Ward, M. P.; Tymensen, L.; Morley, P. S.; Hannon, S.; Booker, C. W.; Read, R. R.; McAllister, T. A.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2018, 82, 1, pp 24-38
Abstract

Background: Anecdotal reports suggest the incidence of right-sided congestive heart failure (RHF) in feedlot cattle is increasing; however, the rate of occurrence and risk factors are largely unknown. Objective: The purposes of this study were to evaluate the risk of RHF over time and among...

Author(s)
Neary, J. M.; Booker, C. W.; Wildman, B. K.; Morley, P. S.
Publisher
Wiley-Blackwell, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2016, 30, 1, pp 326-334
Abstract

Liver abscesses are a major economic burden to beef producers. Although a few causative organisms have been cultured from purulent material, the full polymicrobial diversity of liver abscesses has not been reported. The objective of this study was to characterize purulent material collected from...

Author(s)
Weinroth, M. D.; Carlson, C. R.; Martin, J. N.; Metcalf, J. L.; Morley, P. S.; Belk, K. E.
Publisher
American Society of Animal Science, Savoy, USA
Citation
Journal of Animal Science, 2017, 95, 10, pp 4520-4525
Abstract

The specific antimicrobial resistance (AMR) decreases that can be expected from reducing antimicrobial (AM) use in U.S. beef production have not been defined. To address this data gap, feces were recovered from 36 lots of "raised without antibiotics" (RWA) and 36 lots of "conventional" (CONV) beef ...

Author(s)
Vikram, A.; Rovira, P.; Agga, G. E.; Arthur, T. M.; Bosilevac, J. M.; Wheeler, T. L.; Morley, P. S.; Belk, K. E.; Schmidt, J. W.
Publisher
American Society for Microbiology (ASM), Washington, USA
Citation
Applied and Environmental Microbiology, 2017, 83, 22, pp e01682-17
Abstract

The objectives of this study were to estimate the prevalence of antimicrobial resistance (AMR) and to investigate the associations between exposures to antimicrobial drugs (AMDs) and AMR in fecal non-type specific Escherichia coli (NTSEC) recovered from a large population of feedlot cattle....

Author(s)
Benedict, K. M.; Gow, S. P.; McAllister, T. A.; Booker, C. W.; Hannon, S. J.; Checkley, S. L.; Noyes, N. R.; Morley, P. S.
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2015, 10, 12, pp e0143995

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