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Abstract

The α-adducin (ADD1) is a subunit of adducin which is a cytoskeleton heterodimeric protein. Adducin participates in oocytes chromosome meiosis of mice, prompting adducin has an effect on embryonic development. Adducin gene mutation has significantly functional change. So the present study was to...

Author(s)
Huang YongZhen; Qian LiNa; Wang Jian; Zhang ChunLei; Fang XingTang; Lei ChuZhao; Lan XianYong; Ma Yun; Bai YueYu; Lin FengPeng; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 1, pp 7-12
Abstract

The insulin-like growth factor 1 receptor (IGF1R) plays a vital role in immunomodulation and muscle and bone growth. The copy number variation (CNV) is believed to the reason for many complex phenotypic variations. In this paper, we statistically analyzed the copy number and the expression...

Author(s)
Ma YiLei; Wen YiFan; Cao XiuKai; Cheng Jie; Huang YongZhen; Ma Yun; Hu LinYong; Lei ChuZhao; Qi XingLei; Cao Hui; Chen Hong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2019, 62, 1, pp 171-179
Abstract

Background: Copy number variations (CNVs) are structural variants consisting of large-scale insertions and deletions of genomic fragments. Exploring CNVs and estimating their effects on phenotypes are useful for genome selection but remain challenging in the livestock. Results: We identified 1043...

Author(s)
Liu Mei; Fang LingZhao; Liu ShuLi; Pan, M. G.; Seroussi, E.; Cole, J. B.; Ma Li; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2019, 20, 181, pp (7 March 2019)
Abstract

The growth and development of muscle is a complex and multistage process, which is regulated by many factors. In particular, genes related to muscle development play a very important role. Studies have shown that there are two kinds of regulatory functions of genes affecting muscle development. One ...

Author(s)
Wen YiFan; He Hua; Song ChengChuang; Peng ShuJun; Lei ChuChao; Chen Hong; Huang YongZhen
Publisher
Guangxi University, Guangxi, China
Citation
Genomics and Applied Biology, 2018, 37, 7, pp 2825-2831
Abstract

Author(s)
Zeng LuLan; Huang BiZhi; Li FangYu; Chen NingBo; Ma ZhiJie; Qu KaiXing; Chen Hong; Lei ChuZhao
Publisher
Wiley, Oxford, UK
Citation
Animal Genetics, 2018, 49, 6, pp 655-656
Abstract

Differentiated embryo chondrocyte 1 (DEC1), a member of basic-helix-loop-helix transcription factor Bhlhe40, also called stimulated by retinoic acid 13, STRA13, plays an important role in the regulation of adipogenesis, tumorigenesis, peripheral circadian output, response to hypoxia, and...

Author(s)
Huang YongZhen; Lai XinSheng; Hu LinYong; Lei ChuZhao; Lan XianYong; Zhang ChunLei; Ma Yun; Zheng Li; Bai YueYu; Lin FengPeng; Chen Hong
Publisher
Wiley, Hoboken, USA
Citation
Journal of Cellular Physiology, 2018, 233, 12, pp 9365-9374
Abstract

I-mfa (inhibitor of the MyoD family a) is a transcription modulator that binds to MyoD family members and inhibits their transcriptional activities. It is highly expressed in the sclerotome and plays an important role in the patterning of the somite early in development. In this study, the...

Author(s)
Huang YongZhen; Li JingJing; Zhang ChunLei; Fang XingTang; Lan XianYong; Qi XingLei; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2016, 27, 4, pp 278-286
Abstract

Transmembrane protein 95 (TMEM95) is closely related to male reproductive performance in cattle, but does not affect semen quality. Alternative splicing plays an important role in regulating biological function as well as in generating proteomic and functional diversity in metazoan organisms. Thus, ...

Author(s)
Zhang SiHuan; Cai HanFang; Yang Qing; Shi Tao; Pan ChuanYing; Lei ChuZhao; Dang RuiHua; Chen Hong; Lan XianYong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2016, 575, 2 Part 2, pp 531-536
Abstract

Background: As a major epigenetic component, DNA methylation plays important functions in individual development and various diseases. DNA methylation has been well studied in human and model organisms, but only limited data exist in economically important animals like cattle. Results: Using...

Author(s)
Zhou Yang; Xu LingYang; Bickhart, D. M.; Hay, E. H. A.; Schroeder, S. G.; Connor, E. E.; Alexander, L. J.; Sonstegard, T. S.; Tassell, C. P. van; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2016, 17, 779, pp (6 October 2016)
Abstract

Copy number variations (CNVs) recently have been recognized as another important genetic variability followed single nucleotide polymorphisms (SNPs). The guanylate binding protein 2 (GBP2) gene plays an important role in cell proliferation. This study was performed to determine the presence of GBP2 ...

Author(s)
Zhang GuiMin; Zheng Li; He Hua; Song ChengChuang; Zhang ZiJing; Cao XiuKai; Lei ChuZhao; Lan XianYong; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2018, 647, pp 101-106

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