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Abstract

The study was conducted to analyse Pit-1 gene as a candidate for genetic markers of growth traits in different Chinese cattle. The single-strand conformation polymorphism method was used to detect genetic polymorphism in the Pit-1 gene and intron 5. Results showed that one single nucleotide...

Author(s)
Yang DongYing; Chen Hong; Lan XianYong; Zhang ZhengFeng; Tang LiGang; Zhang LiangZhi; Wang XinZhuang; Wang YiMin; Niu Hui
Publisher
Asian Network for Biotechnology in Animal Production and Health, Haidian, China
Citation
Animal Biotechnology Bulletin, 2006, 10, 1, pp 356-359
Abstract

The identification of copy number variations (CNVs) allow us to explore genomic polymorphisms. In recent years, significant progress in understanding CNVs has been made in studies of human and animals, however, association and expression studies of CNVs are still in the early stage. It was...

Author(s)
Yang MingJuan; Lv JingQiao; Zhang LiangZhi; Li MingXun; Zhou Yang; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2017, 7, 1, pp 46599
Abstract

Cell death-inducing DFFA-like effector c (CIDEC, also known as Fsp27) has emerged as an important regulator of metabolism associated with lipodystrophy, diabetes, and hepatic steatosis. It is required for unilocular lipid droplet formation and optimal energy storage. The mechanism between this gene ...

Author(s)
Wang Jing; Hua LiuShuai; Pan Hong; Zhang LiangZhi; Li MingXun; Huang YongZhen; Li ZhuanJian; Lan XianYong; Lei ChuZhao; Li CongJun; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2015, 5, 1, pp 12075
Abstract

Background: Copy number variations (CNVs) are a main source of genomic structural variations underlying animal evolution and production traits. Here, with one pure-blooded Angus bull as reference, we describe a genome-wide analysis of CNVs based on comparative genomic hybridization arrays in 29...

Author(s)
Zhang LiangZhi; Jia ShanGang; Yang MingJuan; Xu Yao; Li, C. J.; Sun JiaJie; Huang YongZhen; Lan XianYong; Lei ChuZhao; Zhou Yang; Zhang ChunLei; Zhao Xin; Chen Hong
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2014, 15, 480, pp (17 June 2014)
Abstract

Copy number variations (CNVs) recently have been recognized as an important source of genetic variability. Compelling evidence has indicated that CNVs are responsible for phenotypic traits by altering the copy numbers of functional genes. The molecule interacting with CasL-like protein 2 (MICAL-L2) ...

Author(s)
Xu Yao; Zhang LiangZhi; Shi Tao; Zhou Yang; Cai HanFang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
Springer, New York, USA
Citation
Mammalian Genome, 2013, 24, 11/12, pp 508-516
Abstract

DNA methylation is a key epigenetic modification in mammals and plays important roles in muscle development. We sampled longissimus dorsi muscle (LDM) from a well-known elite native breed of Chinese Qinchuan cattle living within the same environment but displaying distinct skeletal muscle at the...

Author(s)
Huang YongZhen; Sun JiaJie; Zhang LiangZhi; Li CongJun; Womack, J. E.; Li ZhuanJian; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Zhao Xin; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2014, 4, 1, pp 06546
Abstract

The Pit-1 gene was studied as a candidate for genetic markers of growth traits in Chinese cattle in this study. The single-strand conformation polymorphism method was used to identify polymorphism in the Pit-1 intron 5. One single nucleotide polymorphism, Pit1I5, was found in intron 5. The...

Author(s)
Tang LiGang; Yang DongYing; Ouyang WuQing; Zhang LiangZhi; Lan XianYong; Zhang ChunLei; Zhang RunFeng; Zhang AiLing; Zhang Li; Chen Hong
Publisher
Academic Journals, Nairobi, Kenya
Citation
African Journal of Biotechnology, 2012, 11, 42, pp 9906-9910
Abstract

As an adaptor protein, SH2B1 is a key regulator of leptin sensitivity, energy balance, growth, and body weight. In this study, we identified three SNPs (snp796, snp823 and snp4368) of the SH2B1 gene in 1028 individuals from five Chinese cattle breeds by PCR-RFLP and sequencing, and investigated...

Author(s)
Yang MingJuan; Qu Lian; Liu JunXia; Lan XianYong; Zhang LiangZhi; Wang Jing; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Livestock Science, 2012, 143, 2/3, pp 283-288
Abstract

Zinc-a2-glycoprotien (AZGP1) involved in lipid metabolism and associated with adipose tissue atrophy in cachexia. And it also related to sperm motility and in turn fertilization. To ascertain whether there were mutations in the bovine AZGP1 gene, this study investigated variation of the AZGP1 gene...

Author(s)
Zhang Bao; Guo YiKun; Li ShengBin; Zhang LiangZhi; Lan XianYong; Hu ShenRong; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2012, 39, 12, pp 10475-10479
Abstract

Studies in humans have independently identified single nucleotide polymorphisms (SNPs) in the fat mass and obesity associated (FTO) gene associated with obesity in multiple populations. It was shown that FTO participated in the regulation of energy homeostasis and associated with increased...

Author(s)
Zhang Bao; Zhang Ya; Zhang LiangZhi; Wang Jing; Li ZhuanJian; Chen Hong
Publisher
Humana Press, Totowa, USA
Citation
Molecular Biotechnology, 2011, 49, 3, pp 257-262

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