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Abstract

Genetic polymorphism has great influences on the improvement of cattle traits. The polymorphism of the same gene family will greatly change the growth traits of cattle, such as the pleomorphic adenoma gene (PLAG) family. Many studies have shown that the PLAG family proteins are the transcription...

Author(s)
Zhong JiaLin; Xu JiaWei; Wang Jian; Wen YiFan; Niu Hui; Zheng Li; He Hua; Peng Kun; He Pan; Shi ShuYue; Huang YinQi; Lei ChuZhao; Dang RuiHua; Lan XianYong; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 689, pp 166-171
Abstract

As a member of MYLK family, MYLK4 gene may play a vital role in muscle development. In this study, one novel single-nucleotide polymorphism (SNP) was identified the bovine MYLK4 by sequencing pooled DNA samples (pool-Seq) and forced polymerase chain reaction-restriction fragment length polymorphism ...

Author(s)
Zheng Li; Zhang GuiMin; Dong YanPeng; Wen YiFan; Dong Dong; Lei ChuZhao; Qi XingLei; Chen Hong; Huo LiJun; Huang YongZhen
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 1, pp 30-35
Abstract

Copy number variation (CNV) related to complex traits, such as disease and quantitative phenotype, is considered an important and wealthy source of genetic and phenotypic diversity. It suggests that the copy number variation of function gene maybe leads to the phenotypic changes. Kupple like factor ...

Author(s)
Xu JiaWei; Zheng Li; Li LiJuan; Yao YuFei; Hua He; Yang ShiZhen; Wen YiFan; Song ChengChuang; Cao XiuKai; Liu KunPeng; Zhang GuiMin; Yang JiaMeng; Hao Dan; Dang RuiHua; Lan XianYong; Lei ChuZhao; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 680, pp 99-104
Abstract

Polymorphisms in the prion protein gene (PRNP) have been linked with the occurrence of transmissible spongiform encephalopathies and the expression of some phenotypic traits in healthy animals including cattle. The aim of this study was to verify the 23-bp insertion/deletion (indel) within promoter ...

Author(s)
Yang Qing; Zhang SiHuan; Liu LiangLiang; Lei ChuZhao; Qi XingLei; Lin FengPeng; Qu WeiDong; Qi XingShan; Liu JiMing; Wang RongMin; Chen Hong; Lan XianYong
Publisher
Taylor & Francis, Abingdon, UK
Citation
Journal of Applied Animal Research, 2018, 46, 1, pp 505-511
Abstract

Polymorphic adenoma gene 1 (PLAG1) is a member of the pleomorphic adenoma gene family. PLAG family of proteins as a nuclear transcription factor mainly play a role in regulating a variety of important genes in the body. The aim of this study was to examine the association of the PLAG1 polymorphism...

Author(s)
Xu Wei; He Hua; Zheng Li; Xu JiaWei; Lei ChuZhao; Zhang GuiMin; Dang RuiHua; Niu Hui; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2018, 675, pp 144-149
Abstract

Adipose tissue plays central role in determining the gustatory quality of beef, but traditional Chinese beef cattle have low levels of fat content. We applied RNA-seq to study the molecular mechanisms underlying adipocyte differentiation in Qinchuan cattle. A total of 18,283 genes were found to be...

Author(s)
Cai HanFang; Li MingXun; Sun XiaoMei; Plath, M.; Li CongJun; Lan XianYong; Lei ChuZhao; Huang YongZhen; Bai YueYu; Qi XingLei; Lin FengPeng; Chen Hong
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Genetics, 2018, 9, October, pp 463
Abstract

Skeletal muscle development is regulated by a series of regulatory factors, and also including noncoding RNA, especially microRNAs (miRNAs). Recently, miR-148a has been found to be involved in murine C2C12 differentiation by targeting ROCK1. However, the function of miR-148a-3p for the...

Author(s)
Song ChengChuang; Yang JiaMeng; Jiang Rui; Yang ZhaoXin; Li Hui; Huang YongZhen; Lan XianYong; Lei ChuZhao; Ma Yun; Qi XingLei; Chen Hong
Publisher
Wiley, Hoboken, USA
Citation
Journal of Cellular Physiology, 2019, 234, 9, pp 15742-15750
Abstract

Growth traits are complex quantitative traits controlled by numerous candidate genes, and they can be well-evaluated using body measurement traits. As the members of the nicotinamide adenine dinucleotide-dependent family of histone deacetylases, class I sirtuin genes (including SIRT1, SIRT2 and ...

Author(s)
Jin YunYun; Yang Qing; Gao JiaYang; Tang Qi; Duan Bo; Yu Ting; Qi XingLei; Liu JiMing; Wang RongMin; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Springer, New York, USA
Citation
Biochemical Genetics, 2018, 56, 6, pp 663-676
Abstract

Paired box 7 (Pax7) gene, a member of the paired box gene family, plays a critical role in animal growth and muscle development, especially in cell proliferation and self-renewal. The aim of this study was to detect the 10 base pair (bp) duplication insertion/deletion (indel) in the promoter region ...

Author(s)
Jin YunYun; Cai HanFang; Liu JiMing; Lin FengPeng; Qi XingLei; Bai YueYu; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 4, pp 469-476
Abstract

Current evidences show that copy number variations (CNVs) are linked to complex phenotypic traits. Leptin receptor (LEPR) gene plays a critical role in energy homeostasis and fat development and re-sequencing of the cattle genome revealed the CNV region (herein referred to as "I3 DNA") within the ...

Author(s)
Shi Tao; Xu Yao; Yang MingJuan; Huang YongZhen; Lan XianYong; Lei ChuZhao; Qi XingLei; Yang XiaoMing; Chen Hong
Publisher
Wiley-Blackwell, Melbourne, Australia
Citation
Animal Science Journal, 2016, 87, 3, pp 336-343

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