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Abstract

Nanog is an important pluripotent transcription regulator transforming somatic cells to induced pluripotent stem cells (iPSCs), and its overexpression leads to a high expression of the growth and differentiation factor 3 (GDF3), which affects animal growth traits. Therefore, the aim of this study...

Author(s)
Zhang Meng; Pan ChuanYing; Lin Qin; Hu SheNrong; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 3, pp 351-361
Abstract

Paired-like homeodomain transcription factor 1 (PITX1) is a pivotal gene in the hypothalamic-pituitary-adrenal axis, which is a well-known pathway affecting lactation performance. The aim of this study was to analyze the DNA methylation profile of the PITX1 gene and its relevance to milk...

Author(s)
Zhao HaiYu; Zhang SiHuan; Wu XianFeng; Pan ChuanYing; Li XiangChen; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2019, 62, 1, pp 59-68
Abstract

Transmembrane protein 95 (TMEM95) is closely related to male reproductive performance in cattle, but does not affect semen quality. Alternative splicing plays an important role in regulating biological function as well as in generating proteomic and functional diversity in metazoan organisms. Thus, ...

Author(s)
Zhang SiHuan; Cai HanFang; Yang Qing; Shi Tao; Pan ChuanYing; Lei ChuZhao; Dang RuiHua; Chen Hong; Lan XianYong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2016, 575, 2 Part 2, pp 531-536
Abstract

The PROP1 protein, encoded by the prophet of Pit-1 (PROP1) gene, exhibits both DNA-binding and transcriptional activation abilities. Its expression leads to the ontogenesis of growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (TSH), and pituitary hormone. The missense mutation H173R ...

Author(s)
Pan ChuanYing; Wu ChongYang; Jia WenChao; Xu Yao; Lei ChuZhao; Hu ShenRong; Lan XianYong; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 531, 2, pp 398-402
Abstract

Objective: The objective of this study was to construct and express the TAT-bSox2-9R fusion vector, which would improve the formation of safe induced pluripotent stem cells using TAT and Poly-Arg (9R) peptides. Method: According to the available coding region of bovine Sox2 gene in GenBank...

Author(s)
Jia WenChao; Gan Peng; Xiong Liang; Pan ChuanYing; Lan XianYong; Chen Hong
Publisher
Northwest A & F University (Natural Science Edition), Yangling, China
Citation
Journal of Northwest A & F University - Natural Science Edition, 2013, 41, 11, pp 1-6
Abstract

GH secretagogue receptor (ghrelin receptor, GHSR) is known to be involved in the control of GH release by mediating the strong stimulatory effect of the endogenous ligand, ghrelin, on GH secretion. Associations between the GHSR gene polymorphism and the growth traits were revealed in Nanyang ...

Author(s)
Zhang Bao; Chen Hong; Guo YiKun; Zhang LiangZhi; Zhao Miao; Lan XianYong; Zhang ChunLei; Pan ChuanYing; Hu ShenRong; Wang JuQiang; Lei ChuZhao
Publisher
Springer, Dordrecht, Netherlands
Citation
Molecular Biology Reports, 2009, 36, 8, pp 2259-2263
Abstract

The AT motif-binding factor (ATBF1), also known as zinc finger homeobox 3 (ZFXH3), is necessary for activating the POU1F1 gene; thus, the ATBF1 gene greatly affects the grow traits in animals. The objective of this work was to explore novel indel (insertion/deletion) variations and their...

Author(s)
Wei ZhenYu; Wang Ke; Hui YiQing; Yan HaiLong; Zhu HaiJing; Qu Lei; Pan ChuanYing; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2018, 61, 3, pp 311-319
Abstract

A conserved gene in meiosis, the Boule gene is involved in meiosis and spermatogenesis. The deletion of this gene in males blocks meiosis and results in infertility. Alternative splicing variants of the Boule gene have been identified in humans, bovines, and bats, but in dairy goats remains...

Author(s)
Zhang XiaoYan; Yu Shuai; Yang Qing; Wang Ke; Zhang SiHuan; Pan ChuanYing; Yan HaiLong; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Elsevier, New York, USA
Citation
Theriogenology, 2018, 116, pp 53-63
Abstract

In this study, polymorphism in the bovine LEPR gene exon 4 was detected by PCR-SSCP and DNA sequencing methods in 653 individuals from five Chinese cattle breeds. Two haplotypes (M and N), three observed genotypes (MM, MN, and NN), and five single nucleotide polymorphisms (SNPs) (NC_007301:g.26767T ...

Author(s)
Guo YiKun; Chen Hong; Lan XianYong; Zhang Bao; Pan ChuanYing; Zhang LiangZhi; Zhang CunFang; Zhao Miao
Publisher
Springer Science + Business Media, Dordrecht, Netherlands
Citation
Biochemical Genetics, 2008, 46, 11/12, pp 828-834
Abstract

Polymorphism of the mtDNA ND5 gene was detected by PCR-SSCP and DNA sequencing methods in 714 individuals from six Chinese cattle breeds. The results showed that at the P2 locus, two kinds of haplotypes, named A and B, with three SNPs (T12900C, A12923T, C12924T) were detected. The frequencies of...

Author(s)
Zhang Bao; Chen Hong; Hua LiuShuai; Zhang ChunLei; Kang XiangTao; Wang XinZhuang; Pan ChuanYing; Lan XianYong; Lei ChuZhao
Publisher
Springer Science + Business Media, Dordrecht, Netherlands
Citation
Biochemical Genetics, 2008, 46, 5/6, pp 362-368

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