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Abstract

Angiopoietin-like protein 6 (ANGPTL6), which plays an important role in angiogenesis and energy metabolism as a circulating orphan peptide secreted by liver, could produce a potential effect on growth and development of animals. The objective of this study was to detect genetic variations of...

Author(s)
Li AiMin; Lan XianYong; Sun XiaoMei; Gao Yuan; Ma Wei; Ma Yun; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2012, 39, 9, pp 9223-9232
Abstract

Zinc-a2-glycoprotien (AZGP1) involved in lipid metabolism and associated with adipose tissue atrophy in cachexia. And it also related to sperm motility and in turn fertilization. To ascertain whether there were mutations in the bovine AZGP1 gene, this study investigated variation of the AZGP1 gene...

Author(s)
Zhang Bao; Guo YiKun; Li ShengBin; Zhang LiangZhi; Lan XianYong; Hu ShenRong; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2012, 39, 12, pp 10475-10479
Abstract

Pituitary homeobox 2 (PITX2) plays crucial roles in embryogenesis, ontogenesis, growth, and development via the Wnt/beta-catenin and POU1F1 pathways. To better understand the characteristics and genetic effects of the cattle PITX2 gene, we identified alternative PITX2 splicings, examined the...

Author(s)
Zhang SiHuan; Xu Han; Kang ZiHong; Cai HanFang; Dang RuiHua; Lei ChuZhao; Chen Hong; Guo Xian; Lan XianYong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2018, 669, pp 1-7
Abstract

Viral infections can play direct or indirect roles in the etiology of the bovine mastitis. Mx dynamin-like GTPase 2 (MX2) gene is a main effector of the antiviral innate immune defense mediated by type I interferon (IFN I), which was demonstrated to confer positive antiviral responses to many...

Author(s)
Chen NingBo; Wang FengQiao; Yu NongQi; Gao Yuan; Huang JiePing; Dang RuiHua; Huang YongZhen; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2018, 29, 2, pp 81-89
Abstract

Apolipoprotein A-II (APOA2) is one of the major constituents of high-density lipoprotein and plays a critical role in lipid metabolism and obesity. However, similar research for the bovine APOA2 gene is lacking. In this study, polymorphisms of the bovine APOA2 gene and its promoter region were...

Author(s)
Zhou Yang; Li CaiXia; Cai HanFang; Xu Yao; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 531, 2, pp 288-293
Abstract

The PROP1 protein, encoded by the prophet of Pit-1 (PROP1) gene, exhibits both DNA-binding and transcriptional activation abilities. Its expression leads to the ontogenesis of growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (TSH), and pituitary hormone. The missense mutation H173R ...

Author(s)
Pan ChuanYing; Wu ChongYang; Jia WenChao; Xu Yao; Lei ChuZhao; Hu ShenRong; Lan XianYong; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 531, 2, pp 398-402
Abstract

Background: MicroRNAs (miRNAs) are a family of ∼22 nucleotide small RNA molecules that regulate gene expression by fully or partially binding to their complementary sequences. Recently, a large number of miRNAs and their expression patterns have been identified in various species. However, to date...

Author(s)
Sun JiaJie; Li MiJie; Li ZhuanJian; Xue Jing; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2013, 14, 42, pp (18 January 2013)
Abstract

Ghrelin is an important peptide that stimulates food intake and regulates energy balance of animals. Single nucleotide polymorphisms of ghrelin gene in three Chinese cattle populations were investigated through PCR-SSCP and DNA sequencing. Five over-lapped DNA fragments were analyzed and a total of ...

Author(s)
Zhang AiLing; Zhang Li; Zhang LiangZhi; Zhang CunFang; Lan XianYong; Zhang ChunLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2012, 39, 6, pp 6981-6986
Abstract

Visfatin, like insulin, induces phosphorylation of signal transduction proteins that operatate downstream of the insulin receptor. The present study is focused on detecting deletion of visfatin gene and analyzing its effect on growth traits in six Chinese cattle breeds (Nangyang, Luxi, Qinchuan,...

Author(s)
Wang Mou; Zhang Ya; Yu Hui; Lai XinSheng; Zhu JinLong; Jiao JinZhen; Lan XianYong; Lei ChuZhao; Zhang LiangZhi; Chen Hong
Publisher
Elsevier B.V., Beijing, China
Citation
Journal of Integrative Agriculture, 2012, 11, 8, pp 1327-1332
Abstract

Growth hormone-releasing hormone (GHRH) is secreted by the hypothalamus and stimulates growth hormone (GH) released from the pituitary. Mutations detected in GHRH gene showed associations with animal production traits. The purpose of this study was to investigate the association of the GHRH gene...

Author(s)
Zhang Bao; Zhao GaoFeng; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2012, 92, 2, pp 243-246

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