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Abstract

Genetic polymorphism has great influences on the improvement of cattle traits. The polymorphism of the same gene family will greatly change the growth traits of cattle, such as the pleomorphic adenoma gene (PLAG) family. Many studies have shown that the PLAG family proteins are the transcription...

Author(s)
Zhong JiaLin; Xu JiaWei; Wang Jian; Wen YiFan; Niu Hui; Zheng Li; He Hua; Peng Kun; He Pan; Shi ShuYue; Huang YinQi; Lei ChuZhao; Dang RuiHua; Lan XianYong; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 689, pp 166-171
Abstract

Copy number variation (CNV) related to complex traits, such as disease and quantitative phenotype, is considered an important and wealthy source of genetic and phenotypic diversity. It suggests that the copy number variation of function gene maybe leads to the phenotypic changes. Kupple like factor ...

Author(s)
Xu JiaWei; Zheng Li; Li LiJuan; Yao YuFei; Hua He; Yang ShiZhen; Wen YiFan; Song ChengChuang; Cao XiuKai; Liu KunPeng; Zhang GuiMin; Yang JiaMeng; Hao Dan; Dang RuiHua; Lan XianYong; Lei ChuZhao; Qi XingLei; Chen Hong; Huang YongZhen
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 680, pp 99-104
Abstract

Polymorphisms in the prion protein gene (PRNP) have been linked with the occurrence of transmissible spongiform encephalopathies and the expression of some phenotypic traits in healthy animals including cattle. The aim of this study was to verify the 23-bp insertion/deletion (indel) within promoter ...

Author(s)
Yang Qing; Zhang SiHuan; Liu LiangLiang; Lei ChuZhao; Qi XingLei; Lin FengPeng; Qu WeiDong; Qi XingShan; Liu JiMing; Wang RongMin; Chen Hong; Lan XianYong
Publisher
Taylor & Francis, Abingdon, UK
Citation
Journal of Applied Animal Research, 2018, 46, 1, pp 505-511
Abstract

Adipose tissue plays central role in determining the gustatory quality of beef, but traditional Chinese beef cattle have low levels of fat content. We applied RNA-seq to study the molecular mechanisms underlying adipocyte differentiation in Qinchuan cattle. A total of 18,283 genes were found to be...

Author(s)
Cai HanFang; Li MingXun; Sun XiaoMei; Plath, M.; Li CongJun; Lan XianYong; Lei ChuZhao; Huang YongZhen; Bai YueYu; Qi XingLei; Lin FengPeng; Chen Hong
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Genetics, 2018, 9, October, pp 463
Abstract

Skeletal muscle development is regulated by a series of regulatory factors, and also including noncoding RNA, especially microRNAs (miRNAs). Recently, miR-148a has been found to be involved in murine C2C12 differentiation by targeting ROCK1. However, the function of miR-148a-3p for the...

Author(s)
Song ChengChuang; Yang JiaMeng; Jiang Rui; Yang ZhaoXin; Li Hui; Huang YongZhen; Lan XianYong; Lei ChuZhao; Ma Yun; Qi XingLei; Chen Hong
Publisher
Wiley, Hoboken, USA
Citation
Journal of Cellular Physiology, 2019, 234, 9, pp 15742-15750
Abstract

Growth traits are complex quantitative traits controlled by numerous candidate genes, and they can be well-evaluated using body measurement traits. As the members of the nicotinamide adenine dinucleotide-dependent family of histone deacetylases, class I sirtuin genes (including SIRT1, SIRT2 and ...

Author(s)
Jin YunYun; Yang Qing; Gao JiaYang; Tang Qi; Duan Bo; Yu Ting; Qi XingLei; Liu JiMing; Wang RongMin; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Springer, New York, USA
Citation
Biochemical Genetics, 2018, 56, 6, pp 663-676
Abstract

Paired box 7 (Pax7) gene, a member of the paired box gene family, plays a critical role in animal growth and muscle development, especially in cell proliferation and self-renewal. The aim of this study was to detect the 10 base pair (bp) duplication insertion/deletion (indel) in the promoter region ...

Author(s)
Jin YunYun; Cai HanFang; Liu JiMing; Lin FengPeng; Qi XingLei; Bai YueYu; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 4, pp 469-476
Abstract

Current evidences show that copy number variations (CNVs) are linked to complex phenotypic traits. Leptin receptor (LEPR) gene plays a critical role in energy homeostasis and fat development and re-sequencing of the cattle genome revealed the CNV region (herein referred to as "I3 DNA") within the ...

Author(s)
Shi Tao; Xu Yao; Yang MingJuan; Huang YongZhen; Lan XianYong; Lei ChuZhao; Qi XingLei; Yang XiaoMing; Chen Hong
Publisher
Wiley-Blackwell, Melbourne, Australia
Citation
Animal Science Journal, 2016, 87, 3, pp 336-343
Abstract

I-mfa (inhibitor of the MyoD family a) is a transcription modulator that binds to MyoD family members and inhibits their transcriptional activities. It is highly expressed in the sclerotome and plays an important role in the patterning of the somite early in development. In this study, the...

Author(s)
Huang YongZhen; Li JingJing; Zhang ChunLei; Fang XingTang; Lan XianYong; Qi XingLei; Chen Hong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2016, 27, 4, pp 278-286
Abstract

Identification of polymorphisms associated with economic traits is important for successful marker-assisted selection in cattle breeding. The family of mammalian sirtuin regulates many biological functions, such as life span extension and energy metabolism. SIRT2, a most abundant sirtuin in...

Author(s)
Sun XiaoMei; Li MingXun; Hao Dan; Hua LiuShuai; Lan XianYong; Lei ChuZhao; Hu ShenRong; Qi XingLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2015, 42, 3, pp 729-736

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