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Abstract

Identification of polymorphisms associated with economic traits is important for successful marker-assisted selection in cattle breeding. The family of mammalian sirtuin regulates many biological functions, such as life span extension and energy metabolism. SIRT2, a most abundant sirtuin in...

Author(s)
Sun XiaoMei; Li MingXun; Hao Dan; Hua LiuShuai; Lan XianYong; Lei ChuZhao; Hu ShenRong; Qi XingLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2015, 42, 3, pp 729-736
Abstract

Cell death-inducing DFFA-like effector c (CIDEC, also known as Fsp27) has emerged as an important regulator of metabolism associated with lipodystrophy, diabetes, and hepatic steatosis. It is required for unilocular lipid droplet formation and optimal energy storage. The mechanism between this gene ...

Author(s)
Wang Jing; Hua LiuShuai; Pan Hong; Zhang LiangZhi; Li MingXun; Huang YongZhen; Li ZhuanJian; Lan XianYong; Lei ChuZhao; Li CongJun; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2015, 5, 1, pp 12075
Abstract

Growth is under complex genetic control and uncovering the molecular mechanisms how the genes and polymorphisms affect economic growth traits, are important for successful marker-assisted selection and more efficient management strategies in commercial cattle populations. SIRT1 is a NAD+-dependent...

Author(s)
Li MingXun; Sun XiaoMei; Hua LiuShuai; Lai XinSheng; Lan XianYong; Lei ChuZhao; Zhang ChunLei; Qi XingLei; Chen Hong
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Molecular and Cellular Probes, 2013, 27, 5/6, pp 215-220
Abstract

Peroxisome proliferators-activated receptor gamma (PPARG) is an important regulator in the regulation of adipose differentiation and development. The mutations of the PPARG in human had been shown to be associated with type II diabetes, fat distribution and body weight. The functional importance of ...

Author(s)
Hua LiuShuai; Wang Jing; Chen FuYing; Hu ShenRong; Chen Hong
Publisher
Academic Journals, Nairobi, Kenya
Citation
African Journal of Biotechnology, 2011, 10, 14, pp 2785-2790
Abstract

Myocyte enhancer factor 2A (MEF2A) gene encodes a member of the myocyte enhancer factor 2 (MEF2) protein family, which involves in vertebrate skeletal muscle development and differentiation. The important function of MEF2A implies this gene is a potential candidate gene for considering association...

Author(s)
Chen FuYing; Chen Hong; Wang JuQiang; Niu Hui; Lan XianYong; Hua LiuShuai; Li ZhuanJian; Lei ChuZhao; Fang XingTang
Publisher
Medwell Online, Faisalabad, Pakistan
Citation
Journal of Animal and Veterinary Advances, 2010, 9, 4, pp 814-819
Abstract

Deleted in breast cancer 1 (DBC1, KIAA1967, p30 DBC) is a novel protein that has been recently shown to bind and regulate SIRT1. Loss of function of DBC1 increased SIRT1 deacetylase activity, which promotes "browning" of WAT by deacetylating peroxisome proliferator-activated receptor (PPARγ) on...

Author(s)
Li MingXun; Sun XiaoMei; Hua LiuShuai; Huang YongZhen; Wang Jing; Cao XiuKai; Zhan ZhaoYang; Lan XianYong; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 527, 2, pp 689-693
Abstract

PCR-RFLP was applied to analyse the polymorphisms of Pit-1 gene in 178 Guyuan local cattle and Limousin × local cattle crossbreds. The association with fattening traits of these polymorphisms was analysed. The 451 bp PCR products digested with Hinf I demonstrated polymorphisms in Guyuan local ...

Author(s)
Hua LiuShuai; Chen Hong; Yang XiaoBing; Yang Qi; Lan XianYong
Publisher
Northwest A & F University (Natural Science Edition), Yangling, China
Citation
Journal of Northwest A & F University - Natural Science Edition, 2007, 35, 12, pp 1-5
Abstract

Polymorphism of the mtDNA ND5 gene was detected by PCR-SSCP and DNA sequencing methods in 714 individuals from six Chinese cattle breeds. The results showed that at the P2 locus, two kinds of haplotypes, named A and B, with three SNPs (T12900C, A12923T, C12924T) were detected. The frequencies of...

Author(s)
Zhang Bao; Chen Hong; Hua LiuShuai; Zhang ChunLei; Kang XiangTao; Wang XinZhuang; Pan ChuanYing; Lan XianYong; Lei ChuZhao
Publisher
Springer Science + Business Media, Dordrecht, Netherlands
Citation
Biochemical Genetics, 2008, 46, 5/6, pp 362-368
Abstract

This study was conducted to detect single nucleotide polymorphisms (SNPs) in the growth hormone secretagogue receptor gene (GHSR) in Chinese cattle breeds using polymerase chain reaction (PCR). Five novel SNPs were found in 649 unrelated animals belonging to 5 breeds (240 Nanyang, 141 Qinchuan, 133 ...

Author(s)
Zhang Bao; Chen Hong; Guo YiKun; Zhang LiangZhi; Hua LiuShuai; Zhao Miao; Lan XianYong; Lei ChuZhao
Publisher
Forschungsinstitut für die Biologie landwirtschaftlicher Nutztiere, Dummerstorf, Germany
Citation
Archiv für Tierzucht, 2007, 50, 6, pp 630-631
Abstract

The 5′ flanking region, the coding region and partial introns of bovine prophet of Pit1 gene (PROP1) were scanned for single nucleotide polymorphisms (SNPs) in 606 Nanyang, Qinchuan, Jiaxian Red, Holstein-Friesian and Angus cattle from China. The alleles of nt349 and nt381 were located in the 5′...

Author(s)
Pan ChuanYing; Lan XianYong; Chen Hong; Hua LiuShuai; Guo YiKun; Zhang Bao; Lei ChuZhao
Publisher
Forschungsinstitut für die Biologie landwirtschaftlicher Nutztiere, Dummerstorf, Germany
Citation
Archiv für Tierzucht, 2007, 50, 4, pp 421-423

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