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Abstract

Nanog is an important pluripotent transcription regulator transforming somatic cells to induced pluripotent stem cells (iPSCs), and its overexpression leads to a high expression of the growth and differentiation factor 3 (GDF3), which affects animal growth traits. Therefore, the aim of this study...

Author(s)
Zhang Meng; Pan ChuanYing; Lin Qin; Hu SheNrong; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 3, pp 351-361
Abstract

Identification of polymorphisms associated with economic traits is important for successful marker-assisted selection in cattle breeding. The family of mammalian sirtuin regulates many biological functions, such as life span extension and energy metabolism. SIRT2, a most abundant sirtuin in...

Author(s)
Sun XiaoMei; Li MingXun; Hao Dan; Hua LiuShuai; Lan XianYong; Lei ChuZhao; Hu ShenRong; Qi XingLei; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2015, 42, 3, pp 729-736
Abstract

Objective: The purpose of this study is to reveal the genetic variation characteristics of bovine ANGPTL6 gene and find several candidate molecular markers that related to growth traits of Luxi cattle, thus for accumulating some basic information for molecular breeding of Luxi cattle breed. Method: ...

Author(s)
Li AiMin; Ma Yun; Yang DongYing; Lan XianYong; Hu ShenRong; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Scientia Agricultura Sinica, Beijing, China
Citation
Scientia Agricultura Sinica, 2012, 45, 11, pp 2306-2314
Abstract

Peroxisome proliferators-activated receptor gamma (PPARG) is an important regulator in the regulation of adipose differentiation and development. The mutations of the PPARG in human had been shown to be associated with type II diabetes, fat distribution and body weight. The functional importance of ...

Author(s)
Hua LiuShuai; Wang Jing; Chen FuYing; Hu ShenRong; Chen Hong
Publisher
Academic Journals, Nairobi, Kenya
Citation
African Journal of Biotechnology, 2011, 10, 14, pp 2785-2790
Abstract

Zinc-a2-glycoprotien (AZGP1) involved in lipid metabolism and associated with adipose tissue atrophy in cachexia. And it also related to sperm motility and in turn fertilization. To ascertain whether there were mutations in the bovine AZGP1 gene, this study investigated variation of the AZGP1 gene...

Author(s)
Zhang Bao; Guo YiKun; Li ShengBin; Zhang LiangZhi; Lan XianYong; Hu ShenRong; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2012, 39, 12, pp 10475-10479
Abstract

The PROP1 protein, encoded by the prophet of Pit-1 (PROP1) gene, exhibits both DNA-binding and transcriptional activation abilities. Its expression leads to the ontogenesis of growth hormone (GH), prolactin (PRL), thyroid-stimulating hormone (TSH), and pituitary hormone. The missense mutation H173R ...

Author(s)
Pan ChuanYing; Wu ChongYang; Jia WenChao; Xu Yao; Lei ChuZhao; Hu ShenRong; Lan XianYong; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 531, 2, pp 398-402
Abstract

SIRT1, a mammalian homologue for yeast silent information regulator 2 (SIR2), is a NAD+-dependent deacetylase that belongs to the class III histone deacetylases. It plays an important role in diverse cellular processes, including stress resistance, mitochondrial function, suppression of...

Author(s)
Li MingXun; Sun XiaoMei; Zhang LiangZhi; Wang Jing; Huang YongZhen; Sun YuJia; Hu ShenRong; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Animal Genetics, 2013, 44, 5, pp 584-587
Abstract

GH secretagogue receptor (ghrelin receptor, GHSR) is known to be involved in the control of GH release by mediating the strong stimulatory effect of the endogenous ligand, ghrelin, on GH secretion. Associations between the GHSR gene polymorphism and the growth traits were revealed in Nanyang ...

Author(s)
Zhang Bao; Chen Hong; Guo YiKun; Zhang LiangZhi; Zhao Miao; Lan XianYong; Zhang ChunLei; Pan ChuanYing; Hu ShenRong; Wang JuQiang; Lei ChuZhao
Publisher
Springer, Dordrecht, Netherlands
Citation
Molecular Biology Reports, 2009, 36, 8, pp 2259-2263
Abstract

Blood and milk samples were collected from 61 Holstein cows in a farm in Xi'an area, China. Somatic cell count (SCC) and pre-somatic cell score (PreSCC) were recorded and somatic cell score (SCS) was calculated. PCR-RFLP (restriction fragment length polymorphism) was carried out on IGFBP-3, β-lg 5' ...

Author(s)
Zhang RunFeng; Chen Hong; Lei ChuZhao; Fang XingTang; Lan XianYong; Hu ShenRong; Su LiHong
Publisher
China Agricultural University, Beijing, China
Citation
Journal of Agricultural Biotechnology, 2007, 15, 1, pp 179-180
Abstract

The study was conducted to identify and characterize polymorphisms within the coding region and the 3′ flanking region of the bovine serotonin receptor 1B gene among different cattle breeds. Four DNA fragments were amplified by polymerase chain reaction and used for polymorphism identification by...

Author(s)
Zhang ChunLei; Chen Hong; Lei ChuZhao; Fang XingTang; Lan XianYong; Zhang Li; Zhang AiLing; Wang JuQiang; Hu ShenRong
Publisher
Editorial Office of Hereditas (Beijing), Beijing, China
Citation
Hereditas (Beijing), 2007, 29, 5, pp 565-569

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