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Abstract

Copy number variations (CNVs) have been recently recognized as another important genetic variability complementary to single nucleotide polymorphisms (SNPs). Compelling evidence has indicated that CNVs are responsible for phenotypic traits by changing the copy numbers of functional genes. Myosin...

Author(s)
Xu Yao; Shi Tao; Cai HanFang; Zhou Yang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Qi XingLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 535, 2, pp 106-111
Abstract

Copy number variations (CNVs) recently have been recognized as an important source of genetic variability. Compelling evidence has indicated that CNVs are responsible for phenotypic traits by altering the copy numbers of functional genes. The molecule interacting with CasL-like protein 2 (MICAL-L2) ...

Author(s)
Xu Yao; Zhang LiangZhi; Shi Tao; Zhou Yang; Cai HanFang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
Springer, New York, USA
Citation
Mammalian Genome, 2013, 24, 11/12, pp 508-516
Abstract

The posttranscriptional gene regulation mediated by microRNAs (miRNAs) plays an important role in various species. Recently, a large number of miRNAs and their expression patterns have been identified. However, to date, limited miRNAs have been reported to modulate adipogenesis and lipid deposition ...

Author(s)
Sun JiaJie; Zhou Yang; Cai HanFang; Lan XianYong; Lei ChuZhao; Zhao Xin; Zhang ChunLei; Chen Hong
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2014, 9, 2, pp e90244
Abstract

Hepatocyte growth factor (HGF) is one of the multifunctional cell factors that regulates cellular proliferation, motility and morphogenesis in mammalians. And its medical research has deep significance. In this paper, polymorphisms of HGF gene were investigated in 1433 health and irrelated Chinese ...

Author(s)
Cai HanFang; Lan XianYong; Li AiMin; Zhou Yang; Sun JiaJie; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2013, 95, 2, pp 483-488
Abstract

The aim of this study was to detect mutations of the nuclear factor I/X (Nfix) gene and examine the association of its polymorphisms with growth traits in cattle. Six sequence variants (SVs) including five single-nucleotide mutations and an indel with multiple alleles were detected, among which...

Author(s)
Zhou Yang; Lan XianYong; Xu Yao; Zhang Bao; Li MiJie; Huang YongZhen; Sun JiaJie; Cai HanFang; Lei ChuZhao; Chen Hong
Publisher
NRC Research Press, Ottawa, Canada
Citation
Genome, 2012, 55, 12, pp 845-851
Abstract

Apolipoprotein A-II (APOA2) is one of the major constituents of high-density lipoprotein and plays a critical role in lipid metabolism and obesity. However, similar research for the bovine APOA2 gene is lacking. In this study, polymorphisms of the bovine APOA2 gene and its promoter region were...

Author(s)
Zhou Yang; Li CaiXia; Cai HanFang; Xu Yao; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2013, 531, 2, pp 288-293
Abstract

Paired box 3 (PAX3) belongs to the PAX superfamily of transcription factors and plays essential roles in the embryogenesis and postnatal formation of limb musculature through affecting the survival of muscle progenitor cells. By genetic mapping, PAX3 gene is assigned in the interval of quantitative ...

Author(s)
Xu Yao; Cai HanFang; Zhou Yang; Shi Tao; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Jia YuTang; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 7, pp 4295-4303
Abstract

Background: Identification of genetic variants, including SNPs (Single Nucleotide Polymorphisms), CNVs (Copy Number Variations) and alternative splicing, within functional genes has received increasing attention in animal science research. HGF (Hepatocyte Growth Factor) is a very important growth...

Author(s)
Cai HanFang; Zhou Yang; Jia WenChao; Zhang BoWen; Lan XianYong; Lei ChuZhao; Fang XinTang; Chen Hong
Publisher
BioMed Central Ltd, London, UK
Citation
Journal of Animal Science and Biotechnology, 2015, 6, 55, pp (22 December 2015)
Abstract

Background: Adipose tissue has long been recognized to play an extremely important role in development. In bovines, it not only serves a fundamental function but also plays a key role in the quality of beef and, consequently, has drawn much public attention. Age and sex are two key factors that...

Author(s)
Zhou Yang; Sun JiaJie; Li, C. J.; Wang YanHong; Li Lan; Cai HanFang; Lan XianYong; Lei ChuZhao; Zhao Xin; Chen Hong
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2014, 9, 7, pp e101261

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