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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

Adipocyte differentiation-associated long noncoding RNA (ADNCR) is a newly discovered lncRNA. It plays function by targeting miR-204 to significantly regulates the expression of the target SIRT1 gene in preadipocytes both at the level of mRNA and protein, thereby inhibiting adipogenesis. The...

Author(s)
Jin YunYun; Yang Qing; Zhang Meng; Zhang SiHuan; Cai HanFang; Dang RuiHua; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Routledge, Philadelphia, USA
Citation
Animal Biotechnology, 2019, 30, 2, pp 159-165
Abstract

Adipose tissue plays central role in determining the gustatory quality of beef, but traditional Chinese beef cattle have low levels of fat content. We applied RNA-seq to study the molecular mechanisms underlying adipocyte differentiation in Qinchuan cattle. A total of 18,283 genes were found to be...

Author(s)
Cai HanFang; Li MingXun; Sun XiaoMei; Plath, M.; Li CongJun; Lan XianYong; Lei ChuZhao; Huang YongZhen; Bai YueYu; Qi XingLei; Lin FengPeng; Chen Hong
Publisher
Frontiers Media S.A., Lausanne, Switzerland
Citation
Frontiers in Genetics, 2018, 9, October, pp 463
Abstract

Angiopoietin-like protein 6, which is encoded by ANGPTL6 gene (also known as angiopoietin growth factor, AGF), has been extensively characterized with regard to its proposed functions as angiogenesis and energy metabolism. The present results showed the occurrence of alternative splicing by intron...

Author(s)
Wu JiYao; Li AiMin; Cai HanFang; Zhang ChenGe; Lei ChuZhao; Lan XianYong; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2019, 709, pp 17-24
Abstract

SMAD3, the messenger of the transforming growth factor beta (TGF-β) signaling pathway, plays essential roles in myogenesis and osteogenesis and may relate to the regulation of body weight. In this study, a 17 bp indel (NC_007308: g.101893_101909 insGAGGATGAGTGCTCCAG) in intron3 of the SMAD3 gene...

Author(s)
Shi Tao; Peng WenWen; Yan JianYu; Cai HanFang; Lan XianYong; Lei ChuZhao; Bai YueYu; Chen Hong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 1, pp 151-157
Abstract

Paired box 7 (Pax7) gene, a member of the paired box gene family, plays a critical role in animal growth and muscle development, especially in cell proliferation and self-renewal. The aim of this study was to detect the 10 base pair (bp) duplication insertion/deletion (indel) in the promoter region ...

Author(s)
Jin YunYun; Cai HanFang; Liu JiMing; Lin FengPeng; Qi XingLei; Bai YueYu; Lei ChuZhao; Chen Hong; Lan XianYong
Publisher
Copernicus Gesellschaft mbH, Gottingen, Germany
Citation
Archives Animal Breeding, 2016, 59, 4, pp 469-476
Abstract

Transmembrane protein 95 (TMEM95) is closely related to male reproductive performance in cattle, but does not affect semen quality. Alternative splicing plays an important role in regulating biological function as well as in generating proteomic and functional diversity in metazoan organisms. Thus, ...

Author(s)
Zhang SiHuan; Cai HanFang; Yang Qing; Shi Tao; Pan ChuanYing; Lei ChuZhao; Dang RuiHua; Chen Hong; Lan XianYong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2016, 575, 2 Part 2, pp 531-536
Abstract

Copy number variations (CNVs) have been recently recognized as another important genetic variability complementary to single nucleotide polymorphisms (SNPs). Compelling evidence has indicated that CNVs are responsible for phenotypic traits by changing the copy numbers of functional genes. Myosin...

Author(s)
Xu Yao; Shi Tao; Cai HanFang; Zhou Yang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Qi XingLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Gene, 2014, 535, 2, pp 106-111
Abstract

Copy number variations (CNVs) recently have been recognized as an important source of genetic variability. Compelling evidence has indicated that CNVs are responsible for phenotypic traits by altering the copy numbers of functional genes. The molecule interacting with CasL-like protein 2 (MICAL-L2) ...

Author(s)
Xu Yao; Zhang LiangZhi; Shi Tao; Zhou Yang; Cai HanFang; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Chen Hong
Publisher
Springer, New York, USA
Citation
Mammalian Genome, 2013, 24, 11/12, pp 508-516
Abstract

The posttranscriptional gene regulation mediated by microRNAs (miRNAs) plays an important role in various species. Recently, a large number of miRNAs and their expression patterns have been identified. However, to date, limited miRNAs have been reported to modulate adipogenesis and lipid deposition ...

Author(s)
Sun JiaJie; Zhou Yang; Cai HanFang; Lan XianYong; Lei ChuZhao; Zhao Xin; Zhang ChunLei; Chen Hong
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2014, 9, 2, pp e90244
Abstract

Hepatocyte growth factor (HGF) is one of the multifunctional cell factors that regulates cellular proliferation, motility and morphogenesis in mammalians. And its medical research has deep significance. In this paper, polymorphisms of HGF gene were investigated in 1433 health and irrelated Chinese ...

Author(s)
Cai HanFang; Lan XianYong; Li AiMin; Zhou Yang; Sun JiaJie; Lei ChuZhao; Zhang ChunLei; Chen Hong
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2013, 95, 2, pp 483-488

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