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Abstract

Larval migration inhibition (LMI) activity of abomasal mucus from calves naturally infected with gastrointestinal nematodes was studied in vitro. LMI activity was also assessed in serum from calves during both natural and artificial O. ostertagi infections to monitor the development of acquired...

Author(s)
Claerebout, E.; Agneessens, J.; Shaw, D. J.; Vercruysse, J.
Citation
Research in Veterinary Science, 1999, 66, 3, pp 253-257
Abstract

Over a period of 1 year, from November 1997 to October 1998, the abomasa, blood and faecal samples of 121 dairy cows in Belgium were collected and examined for nematode infections. Nematodes were present in the abomasa of 110 animals. Ostertagia ostertagi was found in all 110, Trichostrongylus was...

Author(s)
Agneessens, J.; Claerebout, E.; Dorny, P.; Borgsteede, F. H. M.; Vercruysse, J.
Citation
Veterinary Parasitology, 2000, 90, 1/2, pp 83-92
Abstract

The present study reports on the development of a copro-antigen capture ELISA for detecting Ostertagia ostertagi infections in cattle. The ELISA was based on polyclonal rabbit antibodies, which recognize O. ostertagi excretory/secretory (ES) antigens. ES antigens are released by the metabolic...

Author(s)
Agneessens, J.; Claerebout, E.; Vercruysse, J.
Publisher
Elsevier Science B.V., Amsterdam, Netherlands
Citation
Veterinary Parasitology, 2001, 97, 3, pp 227-238
Abstract

As an alternative to antihelminthic drugs, we are exploiting vaccination to control infections with the abomasal nematode Ostertagia ostertagi in cattle. Our focus for vaccine targets is excretory-secretory (ES) products of this parasite. One of the most abundant antigens in larval and adult ...

Author(s)
Vercauteren, I.; Geldhof, P.; Vercruysse, J.; Peelaers, I.; Broeck, W. van den; Gevaert, K.; Claerebout, E.
Publisher
American Society for Microbiology (ASM), Washington, USA
Citation
Infection and Immunity, 2004, 72, 5, pp 2995-3001
Abstract

The objective of this study was to evaluate abomasal cytokine responses in helminth-naive calves and calves vaccinated with protective antigen fractions from Ostertagia ostertagi after an experimental challenge infection with infective third stage (L3) larvae. Abomasal lymph nodes and/or abomasal...

Author(s)
Claerebout, E.; Vercauteren, I.; Geldhof, P.; Olbrechts, A.; Zarlenga, D. S.; Goddeeris, B. M.; Vercruysse, J.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Parasite Immunology, 2005, 27, 9, pp 325-331
Abstract

The transthyretin-like (ttl) gene family is one of the largest conserved nematode-specific gene families, coding for a group of proteins with significant sequence similarity to transthyretins (TTR) and transthyretin-related proteins (TRP). In the present study, we investigated the ttl family in ...

Author(s)
Saverwyns, H.; Visser, A.; Durme, J. van; Power, D.; Morgado, I.; Kennedy, M. W.; Knox, D. P.; Schymkowitz, J.; Rousseau, F.; Gevaert, K.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
International Journal for Parasitology, 2008, 38, 13, pp 1545-1556
Abstract

The mucus layer in the gastrointestinal (GI) tract is considered to be the first line of defense to the external environment. Alteration in mucus components has been reported to occur during intestinal nematode infection in ruminants, but the role of mucus in response to abomasal parasites remains...

Author(s)
Rinaldi, M.; Dreesen, L.; Hoorens, P. R.; Li, R. W.; Claerebout, E.; Goddeeris, B.; Vercruysse, J.; Broek, W. van den; Geldhof, P.
Publisher
BioMed Central Ltd, London, UK
Citation
Veterinary Research, 2011, 42, 61, pp (11 May 2011)
Abstract

Ostertagia ostertagi is considered one of the most economically important bovine parasites. As an alternative to anthelmintic treatment, an experimental host-protective vaccine was previously developed on the basis of ASP proteins derived from adult worms. Intramuscular injection of this vaccine,...

Author(s)
Meulder, F. van; Coppernolle, S. van; Borloo, J.; Rinaldi, M.; Li, R. W.; Chiers, K.; Broeck, W. van den; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
American Society for Microbiology (ASM), Washington, USA
Citation
Infection and Immunity, 2013, 81, 5, pp 1798-1809

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