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VetMed Resource

Veterinary information to support practice, based on evidence and continuing education

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Abstract

A differential rate of uptake of fenbendazole had been thought to account for its lower efficiency against the 4th stage larva (EL4). This was tested by giving large amounts of the isotope labelled anthelmintic to 4 infected calves, but testing recovered adult and larvae revealed no difference in...

Author(s)
Prichard, R. K.; Donald, A. D.; Dash, K. M.; Hennessy, D. R.
Citation
Veterinary Record, 1978, 102, 17, pp 382
Abstract

Cambendazole (CBZ), fenbendazole (FBZ), oxfendazole (OFZ) and thiabendazole (TBZ) all inhibited the fumarate-stimulated oxidation of NADH in Haemonchus contortus mitochondria. These observations plus the phenomenon of cross resistance to benzimidazoles suggested that the different benzimidazoles...

Author(s)
Prichard, R. K.; Hennessy, D. R.; Steel, J. W.
Citation
Veterinary Parasitology, 1978, 4, 4, pp 309-315
Abstract

Three of 6 10- to 12-month-old steers given a single drench of 700 mg thiabendazole/kg body-weight (8 times the normal dose) became very agitated 10 min after drenching. Within 20 min there was a loss of control of forelimbs, followed shortly after by total collapse. One animal died within 30 min...

Author(s)
Hennessy, D. R.; Prichard, R. K.
Citation
Australian Veterinary Journal, 1979, 55, 6, pp 298
Abstract

Oxfendazole (OFZ) was chemically modified to 1-n-butyl carbamoyl OFZ (C4-OFZ) in an attempt to improve the solubility of OFZ and enable it to be administered by injection. After intramuscular injection to sheep and cattle, C4-OFZ was metabolised to OFZ which resulted in higher plasma OFZ...

Author(s)
Hennessy, D. R.; Lacey, E.; Prichard, R. K.
Citation
Veterinary Research Communications, 1983, 6, 3, pp 177-187
Abstract

Author(s)
Davidson, S.
Citation
Rural Research, CSIRO, 1983, No.120, pp 9-12
Abstract

Newer methods of administering anthelmintics, which can be more effective in treating cattle and sheep infected with nematodes than the oral drenches normally employed, are discussed.

Author(s)
Prichard, R. K.
Citation
Span, 1985, 28, 2, pp 72-74
Abstract

Author(s)
Steel, J. W.; Hennessy, D. R.; Lacey, E.; Prichard, R. K.
Citation
New Zealand Journal of Zoology, 1985, 12, 3, pp 449
Abstract

Anthelmintic control of Ostertagia ostertagi in cattle presents some special problems because the arrested larval stage (hypobiotic EL4) tolerates all of the older anthelmintics. The only anthelmintics on the North American market that are effective against this atage as well as the adult and...

Author(s)
Prichard, R. K.
Citation
Veterinary Parasitology, 1988, 27, 1, pp 97-109
Abstract

Resistance has now been reported to all of the broad spectrum anthelmintic types currently available, namely to the benzimidazoles, levamisole/morantel and to ivermectin. The problem causes most concern for parasite control in sheep, but anthelmintic resistance has also been reported in nematodes...

Author(s)
Prichard, R. K.
Citation
International Journal for Parasitology, 1990, 20, 4, pp 515-523
Abstract

The efficacy of moxidectin, a new endectocide against natural nematode infections, was evaluated. 25 calves were divided into 2 groups of 8 calves each and a 3rd group of 9 calves served as controls. Moxidectin was administered sc to 2 groups (I, 0.2 mg/kg bwt; II, 0.3 mg/kg bwt) and the 3rd group...

Author(s)
Ranjan, S.; Trudeau, C.; Prichard, R. K.; Kutzleben, R. von; Carrier, D.
Citation
Veterinary Parasitology, 1992, 41, 3-4, pp 227-231

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