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Abstract

Excretory-secretory (ES) products of Ostertagia ostertagi, an abomasal nematode of cattle, are considered to be important for the development and survival of the parasite within the host. To gain insight in the composition of these ES products of both larval (L3, L4) and adult life stages of ...

Author(s)
Vercauteren, I.; Geldhof, P.; Peelaers, I.; Claerebout, E.; Berx, G.; Vercruysse, J.
Publisher
Elsevier Science Ltd, Oxford, UK
Citation
Molecular and Biochemical Parasitology, 2003, 126, 2, pp 201-208
Abstract

As an alternative to antihelminthic drugs, we are exploiting vaccination to control infections with the abomasal nematode Ostertagia ostertagi in cattle. Our focus for vaccine targets is excretory-secretory (ES) products of this parasite. One of the most abundant antigens in larval and adult ...

Author(s)
Vercauteren, I.; Geldhof, P.; Vercruysse, J.; Peelaers, I.; Broeck, W. van den; Gevaert, K.; Claerebout, E.
Publisher
American Society for Microbiology (ASM), Washington, USA
Citation
Infection and Immunity, 2004, 72, 5, pp 2995-3001
Abstract

Activation associated secreted proteins (ASP) are members of a nematode-specific protein family belonging to the SCP/Tpx-1/Ag5/PR-1/Sc7 family. Three different types of molecules have been identified in this family: two-domain ASPs and single-domain ASPs showing homology to either the C-terminal or ...

Author(s)
Visser, A.; Zeveren, A. M. van; Meyvis, Y.; Peelaers, I.; Broeck, W. van den; Gevaert, K.; Vercruysse, J.; Claerebout, E.; Geldhof, P.
Publisher
Elsevier, Oxford, UK
Citation
International Journal for Parasitology, 2008, 38, 3/4, pp 455-465
Abstract

The cysteine-rich secretory/antigen 5/pathogenesis-related 1 (CAP) protein superfamily is composed of a functionally diverse group of members that are found in both eukaryotes and prokaryotes. The excretome/secretome of numerous helminths (parasitic nematodes) contains abundant amounts of CAP...

Author(s)
Borloo, J.; Geldhof, P.; Peelaers, I.; Meulder, F. van; Ameloot, P.; Callewaert, N.; Vercruysse, J.; Claerebout, E.; Strelkov, S. V.; Weeks, S. D.
Publisher
Wiley-Blackwell, Copenhagen, Denmark
Citation
Acta Crystallographica Section D, Biological Crystallography, 2013, 69, 4, pp 493-503

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