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Abstract

Paired box 7 (PAX7) gene regulates the conversion of muscle satellite cells into myogenic cells and participates in multi-step processes in myogenesis. Expression levels of PAX7 are decisive for its regulatory function. Previous reports revealed that PAX7 were responsible for the developmental...

Author(s)
Xu Yao; Shi Tao; Zhou Yang; Liu Mei; Klaus, S.; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2018, 8, 1, pp 1724
Abstract

Background: Copy number variation (CNV) is an important type of genetic variation contributing to phenotypic differences among mammals and may serve as an alternative molecular marker to single nucleotide polymorphism (SNP) for genome-wide association study (GWAS). Recently, GWAS analysis using CNV ...

Author(s)
Zhou Yang; Connor, E. E.; Wiggans, G. R.; Lu YongFang; Tempelman, R. J.; Schroeder, S. G.; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2018, 19, 314, pp (2 May 2018)
Abstract

The identification of copy number variations (CNVs) allow us to explore genomic polymorphisms. In recent years, significant progress in understanding CNVs has been made in studies of human and animals, however, association and expression studies of CNVs are still in the early stage. It was...

Author(s)
Yang MingJuan; Lv JingQiao; Zhang LiangZhi; Li MingXun; Zhou Yang; Lan XianYong; Lei ChuZhao; Chen Hong
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2017, 7, 1, pp 46599
Abstract

Background: As a major epigenetic component, DNA methylation plays important functions in individual development and various diseases. DNA methylation has been well studied in human and model organisms, but only limited data exist in economically important animals like cattle. Results: Using...

Author(s)
Zhou Yang; Xu LingYang; Bickhart, D. M.; Hay, E. H. A.; Schroeder, S. G.; Connor, E. E.; Alexander, L. J.; Sonstegard, T. S.; Tassell, C. P. van; Chen Hong; Liu, G. E.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2016, 17, 779, pp (6 October 2016)
Abstract

Flightless-1 (FLII) is essential for early embryogenesis, structural organization of indirect flight muscle and can inhibit adipocyte differentiation. We therefore aimed to identify common variations in FLII gene and to investigate their effects on cattle growth traits. By DNA sequencing and forced ...

Author(s)
Liu Mei; Liu Min; Li Bo; Zhou Yang; Huang YongZhen; Lan XianYong; Qu WeiDong; Qi XingShan; Bai YueYu; Chen Hong
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Molecular and Cellular Probes, 2016, 30, 4, pp 266-272
Abstract

Background: Identification of genetic variants, including SNPs (Single Nucleotide Polymorphisms), CNVs (Copy Number Variations) and alternative splicing, within functional genes has received increasing attention in animal science research. HGF (Hepatocyte Growth Factor) is a very important growth...

Author(s)
Cai HanFang; Zhou Yang; Jia WenChao; Zhang BoWen; Lan XianYong; Lei ChuZhao; Fang XinTang; Chen Hong
Publisher
BioMed Central Ltd, London, UK
Citation
Journal of Animal Science and Biotechnology, 2015, 6, 55, pp (22 December 2015)
Abstract

Background: Adipose tissue has long been recognized to play an extremely important role in development. In bovines, it not only serves a fundamental function but also plays a key role in the quality of beef and, consequently, has drawn much public attention. Age and sex are two key factors that...

Author(s)
Zhou Yang; Sun JiaJie; Li, C. J.; Wang YanHong; Li Lan; Cai HanFang; Lan XianYong; Lei ChuZhao; Zhao Xin; Chen Hong
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2014, 9, 7, pp e101261
Abstract

Paired box 3 (PAX3) belongs to the PAX superfamily of transcription factors and plays essential roles in the embryogenesis and postnatal formation of limb musculature through affecting the survival of muscle progenitor cells. By genetic mapping, PAX3 gene is assigned in the interval of quantitative ...

Author(s)
Xu Yao; Cai HanFang; Zhou Yang; Shi Tao; Lan XianYong; Zhang ChunLei; Lei ChuZhao; Jia YuTang; Chen Hong
Publisher
Springer, Amsterdam, Netherlands
Citation
Molecular Biology Reports, 2014, 41, 7, pp 4295-4303
Abstract

Background: Copy number variations (CNVs) are a main source of genomic structural variations underlying animal evolution and production traits. Here, with one pure-blooded Angus bull as reference, we describe a genome-wide analysis of CNVs based on comparative genomic hybridization arrays in 29...

Author(s)
Zhang LiangZhi; Jia ShanGang; Yang MingJuan; Xu Yao; Li, C. J.; Sun JiaJie; Huang YongZhen; Lan XianYong; Lei ChuZhao; Zhou Yang; Zhang ChunLei; Zhao Xin; Chen Hong
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Genomics, 2014, 15, 480, pp (17 June 2014)
Abstract

The posttranscriptional gene regulation mediated by microRNAs (miRNAs) plays an important role in various species. Recently, a large number of miRNAs and their expression patterns have been identified. However, to date, limited miRNAs have been reported to modulate adipogenesis and lipid deposition ...

Author(s)
Sun JiaJie; Zhou Yang; Cai HanFang; Lan XianYong; Lei ChuZhao; Zhao Xin; Zhang ChunLei; Chen Hong
Publisher
Public Library of Sciences (PLoS), San Francisco, USA
Citation
PLoS ONE, 2014, 9, 2, pp e90244

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