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Abstract

This study evaluated the outcome of cats with diabetes mellitus treated with a loose-control approach using protamine zinc insulin and identified factors that influence the likelihood of remission and survival in these cats. A total of 185 client-owned domestic cats were followed until death, lost...

Author(s)
Restine, L. M.; Norsworthy, G. D.; Kass, P. H.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2019, 60, 4, pp 399-404
Abstract

Protamine zinc insulin use has been described in cats. To evaluate the available scientific information upon its pharcokinetics and clinical efficiency, a systematic review of litterature has been conducted in three medical databases. Eleven papers respond to the inclusion criteria. The analysis of ...

Author(s)
Boedec, K. le
Publisher
Newsmed, Paris, France
Citation
Point Vétérinaire, 2016, 47, 370 (Part 1), pp 38-44
Abstract

Objectives: The objective was to evaluate a nadir-led protocol for transitioning porcine lente insulin suspension (PLIS)-treated diabetic cats onto human recombinant protamine zinc insulin (PZIR). Methods: Recently diagnosed (<5 months) diabetic cats, treated with PLIS q12h for ≥6 weeks, were recruited. Fructosamine,...

Author(s)
Gostelow, R.; Hazuchova, K.; Scudder, C.; Forcada, Y.; Church, D.; Niessen, S. J. M.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2018, 20, 2, pp 114-121
Abstract

Background: Little information is available about posthypoglycemic hyperglycemia (PHH) in diabetic cats, and a causal link between hypoglycemia and subsequent hyperglycemia is not clear. Fluctuations in blood glucose concentrations might only represent high glycemic variability. Hypothesis: Insulin ...

Author(s)
Zini, E.; Salesov, E.; Dupont, P.; Moretto, L.; Contiero, B.; Lutz, T. A.; Reusch, C. E.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2018, 32, 3, pp 978-985
Abstract

With the aim to improve current therapeutic and monitoring options for diabetic cats, the present study compared pharmacodynamic parameters of protamine zinc insulin (PZI) and insulin degludec and validated the continuous glucose monitoring system (CGMS) iPro2 with Sof-sensor and Enlite-sensor...

Author(s)
Salesov, E.; Zini, E.; Riederer, A.; Lutz, T. A.; Reusch, C. E.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Research in Veterinary Science, 2018, 118, pp 79-85
Abstract

Case summary: An 8-year-old male neutered Persian cat was presented with polyuria, polydipsia, polyphagia and muscle weakness associated with a 7 month history of diabetes mellitus (DM). The cat had initially been treated with neutral protamine Hagedorn (NPH) insulin 2 U q12h, followed by porcine...

Author(s)
Muschner, A. C.; Varela, F. V.; Hazuchova, K.; Niessen, S. J. M.; Pöppl, Á. G.
Publisher
Sage Publications Ltd, London, UK
Citation
Journal of Feline Medicine and Surgery Open Reports, 2018, 4, 1, pp 2055116918767708
Abstract

Objectives: The aim of the study was to evaluate circulating insulin-like growth factor-1 (IGF-1), feline pancreas-specific lipase (fPLI) and total thyroxine (TT4) concentrations and urinary corticoid-to-creatinine ratio (UCCR) as indicators for the prevalence of acromegaly, pancreatitis,...

Author(s)
Schaefer, S.; Kooistra, H. S.; Riond, B.; Suchodolski, J. S.; Steiner, J. M.; Prins, M.; Zini, E.; Reusch, C. E.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2017, 19, 8, pp 888-896
Abstract

The objective of this study was to report owner experiences and satisfaction in treating a pet with diabetes mellitus using a descriptive report from an Internet-based survey. Descriptive analysis of results was performed, χ2 tests were used to detect differences in responses between dog and cat...

Author(s)
Aptekmann, K. P.; Armstrong, J.; Coradini, M.; Rand, J.
Publisher
American Animal Hospital Association, Denver, USA
Citation
Journal of the American Animal Hospital Association, 2014, 50, 4, pp 247-253
Abstract

Glycaemic control and remission probabilities were compared in 24 newly diagnosed diabetic cats treated twice daily with either glargine, protamine zinc (PZI) or lente insulin and fed a low carbohydrate diet. After day 17, the probability of remission was substantially higher for cats with lower...

Author(s)
Marshall, R. D.; Rand, J. S.; Mort, J. M.
Publisher
Elsevier, Amsterdam, Netherlands
Citation
Journal of Feline Medicine and Surgery, 2009, 11, 8, pp 683-691
Abstract

Background: This study describes the efficacy of a new protamine zinc recombinant human insulin (PZIR) preparation for treating diabetic cats. Objective: To evaluate effects of PZIR on control of glycemia in cats with newly diagnosed or poorly controlled diabetes mellitus. Animals: One hundred and...

Author(s)
Nelson, R. W.; Henley, K.; Cole, C.
Publisher
Blackwell Publishing, Oxford, UK
Citation
Journal of Veterinary Internal Medicine, 2009, 23, 4, pp 787-793

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