Objective: To estimate the pharmacokinetics of midazolam and 1-hydroxymidazolam after midazolam administration as an intravenous bolus in sevoflurane-anesthetized cats. Study design: Prospective pharmacokinetic study. Animals: A group of six healthy adult, female domestic cats. Methods: Anesthesia...
Author(s)
Dholakia, U.; Seddighi, R. M.; Cox, S. K.; Sun XiaoCun; Pypendop, B. H.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 2, pp 200-209
Two healthy research cats involved in a randomized, blinded prospective pharmacodynamics study evaluating midazolam continuous-rate infusion as a means to decrease sevoflurane concentrations experienced unexpectedly prolonged recoveries. Midazolam loading doses, infusion rates, and the targeted...
Author(s)
Dholakia, U.; Seddighi, R.; Odunayo, A.; Cox, S. K.; Jones, E. H.; Pypendop, B. H.
Publisher
American Association for Laboratory Animal Science, Memphis, USA
Citation
Comparative Medicine, 2019, 69, 4, pp 321-326
Objective: To investigate the median effective dose 50 (ED50) of midazolam required for endotracheal intubation when used for co-induction of anesthesia with a low dose of alfaxalone in sedated cats. Study design: Randomized up-and-down study. Animals: A group of 14 mixed-breed cats (eight males,...
Author(s)
Lagos-Carvajal, A.; Queiroz-Williams, P.; Cunha, A. da; Liu ChinChi
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 3, pp 299-307
The efficacy, safety, physiologic effects, and reversibility of butorphanol-medetomidine-midazolam (BMM) immobilization were evaluated in black-footed cats (Felis nigripes) and compared between captive and wild animals. Nine captive and 14 wild black-footed cats were hand injected into an...
Author(s)
Eggers, B.; Tordiffe, A. S. W.; Lamberski, N.; Lawrenz, A.; Sliwa, A.; Wilson, B.; Meyer, L. C. R.
Publisher
American Association of Zoo Veterinarians, Pomona, USA
Citation
Journal of Zoo and Wildlife Medicine, 2020, 51, 3, pp 497-506
The aim of this study was to compare cardiorespiratory changes and post-operative analgesia provided by dexmedetomidine or tramadol, associated with midazolam, in female cats. For that purpose, 18 healthy cats were assigned to two randomized groups: GDM, which received dexmedetomidine (10 µg/kg)...
Author(s)
Lemos, V. C. C.; Sande, J. Q.; Barbosa, V. F.; Costa Neto, J. M.; Martins Filho, E. F.; Iwassa, C. H. D.
Publisher
FEPMVZ - Editora, Belo Horizonte, Brazil
Citation
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2017, 69, 6, pp 1521-1528
The objective of this study was to determine the effects of propofol and midazolam on induction of anesthesia in cats undergoing ovariohysterectomy, measured in terms of the quality of tracheal intubation, anesthesia induction, cardiorespiratory effects, and recuperation period. Thirty healthy...
Author(s)
Castro, D. G. de; Caldeira, J. de A.; Devito, F. C.; Melo, S. R.; Cortopassi, S. R. G.
Publisher
Universidade Estadual de Londrina, Londrina, Brazil
Citation
Semina: Ciências Agrárias (Londrina), 2015, 36, 6 Suppl. 2, pp 4269-4276
Intramuscular administration of ketamine-midazolam was used as a fast-acting chemical restraint, with convenient use of the drug in domestic cats. Furthermore, biochemical and hematological changes were evaluated following administration. A total of 20 clinically healthy cats were selected. During...
Author(s)
Heidari, F.; Javdani, M.; Sadegh, A. B.; Nikouseft, Z.
Publisher
Springer Science + Business Media, London, UK
Citation
Comparative Clinical Pathology, 2017, 26, 4, pp 793-797
This study evaluated the effects of ketamine-dexmedetomidine-midazolam as part of an opioid-free, multimodal protocol in cats undergoing ovariohysterectomy. In a prospective, blinded, randomized clinical trial, cats received either 1 of 2 doses of ketamine [5 mg/kg body weight (BW), n = 10, K5 or 7 ...
Author(s)
Truc Ngoc Diep; Monteiro, B. P.; Evangelista, M. C.; Balleydier, A.; Watanabe, R.; Ruel, H. L. M.; Doodnaught, G. M.; Thong Le Quang; Steagall, P. V.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Veterinary Journal, 2020, 61, 6, pp 621-628
Propofol is the most frequent drug used for induction of anesthesia in small animals. Its cardiovascular and respiratory depressor effects are well known. The association with other drugs would determinate a reduction of its dose, and this possibility is little known in cats. In the present study,...
Author(s)
Castro, D. G. de
Publisher
Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil
Citation
Efeitos do Midazolam associado ao propofol na indução da anestesia de gatas submetidas a ovário-salpingo-histerectomia, 2010, pp 126 pp.
Objectives: Assess effects of benzodiazepine administration on the propofol dose required to induce anaesthesia in healthy cats, investigate differences between midazolam and diazepam, and determine an optimal benzodiazepine dose for co-induction. Study design: Prospective, randomised, blinded,...
Author(s)
Robinson, R.; Borer-Weir, K.
Publisher
Wiley-Blackwell, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2015, 42, 5, pp 493-501