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Abstract

Objective: To estimate the pharmacokinetics of midazolam and 1-hydroxymidazolam after midazolam administration as an intravenous bolus in sevoflurane-anesthetized cats. Study design: Prospective pharmacokinetic study. Animals: A group of six healthy adult, female domestic cats. Methods: Anesthesia...

Author(s)
Dholakia, U.; Seddighi, R. M.; Cox, S. K.; Sun XiaoCun; Pypendop, B. H.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2020, 47, 2, pp 200-209
AbstractFull Text

The aim of this study was to compare the effects of midazolam-ketamine alone or in combination with dexmedetomidine or tramadol in a constant rate infusion (CRI) on the minimum infusion rate (MIR) of propofol and the cardiorespiratory function in cats undergoing an ovariohysterectomy (OH). This was ...

Author(s)
Souza, T.; Anjos, N. dos; Kersul, I.; Martins Filho, E.; Nunes, T.; Barbosa, V.
Publisher
Czech Academy of Agricultural Sciences, Prague, Czech Republic
Citation
Veterinární Medicína, 2022, 67, 4, pp 199-205
Abstract

Two healthy research cats involved in a randomized, blinded prospective pharmacodynamics study evaluating midazolam continuous-rate infusion as a means to decrease sevoflurane concentrations experienced unexpectedly prolonged recoveries. Midazolam loading doses, infusion rates, and the targeted...

Author(s)
Dholakia, U.; Seddighi, R.; Odunayo, A.; Cox, S. K.; Jones, E. H.; Pypendop, B. H.
Publisher
American Association for Laboratory Animal Science, Memphis, USA
Citation
Comparative Medicine, 2019, 69, 4, pp 321-326
Abstract

Pethidine is a synthetic opioid that is widely used in cats. However, the sedative, cardiorespiratory, and histaminic effects following administration of pethidine with midazolam in cats remain unclear. The objectives of this study were to evaluate and compare changes before and after intravenous...

Author(s)
Yang NianYao; Ko, J. C.; Wang HsienChi; Liu PinChen
Publisher
Elsevier, Oxford, UK
Citation
Veterinary and Animal Science, 2021, 14,
Abstract

Objective: To investigate the median effective dose 50 (ED50) of midazolam required for endotracheal intubation when used for co-induction of anesthesia with a low dose of alfaxalone in sedated cats. Study design: Randomized up-and-down study. Animals: A group of 14 mixed-breed cats (eight males,...

Author(s)
Lagos-Carvajal, A.; Queiroz-Williams, P.; Cunha, A. da; Liu ChinChi
Publisher
Elsevier Ltd, Oxford, UK
Citation
Veterinary Anaesthesia and Analgesia, 2019, 46, 3, pp 299-307
Abstract

This study aimed to elucidate whether midazolam affected the learning and memory of rats through the extracellular signalregulated kinase (ERK)/cyclic adenosine monophosphate response element-binding (CREB) signaling pathway and hippocampal oxidative damage. Overall 120 Wistar rats were randomly...

Author(s)
Zhao MingChao; Ma TianWen; Song XiaoPeng; Zhou Tong; Chen Hong; Tang JiLang; Wang XinYu; Liu Lin; Bai Hui; Gao Li
Publisher
Northeast Agricultural University, Harbin, China
Citation
Journal of Northeast Agricultural University (English Edition), 2022, 29, 3, pp 48-58
AbstractFull Text

This study examined the post-operative effects of atipamezole (Ati) and flumazenil (Flu) on stress-related neurohormonal and metabolic responses in isoflurane-anesthetized cats premedicated with medetomidine, midazolam and ketamine and undergoing ovariohysterectomy or castration. Client-owned...

Author(s)
Kamohara, H.; Kamohara, T.; Hikasa, Y.
Publisher
Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand
Citation
Thai Journal of Veterinary Medicine, 2022, 52, 1, pp 167-175
Abstract

Objectives: The aim of this pilot study was to compare the quality of sedation and ease of intravenous (IV) catheter placement following sedation using two intramuscular (IM) sedation protocols in cats: hydromorphone, alfaxalone and midazolam vs hydromorphone and alfaxalone. Methods: This was a...

Author(s)
Wheeler, E. P.; Abelson, A. L.; Lindsey, J. C.; Wetmore, L. A.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2021, 23, 12, pp 1109-1116
Abstract

The efficacy, safety, physiologic effects, and reversibility of butorphanol-medetomidine-midazolam (BMM) immobilization were evaluated in black-footed cats (Felis nigripes) and compared between captive and wild animals. Nine captive and 14 wild black-footed cats were hand injected into an...

Author(s)
Eggers, B.; Tordiffe, A. S. W.; Lamberski, N.; Lawrenz, A.; Sliwa, A.; Wilson, B.; Meyer, L. C. R.
Publisher
American Association of Zoo Veterinarians, Pomona, USA
Citation
Journal of Zoo and Wildlife Medicine, 2020, 51, 3, pp 497-506
AbstractFull Text

The aim of this clinical trial was to evaluate the impacts of administration via the intrarectal route (IR) in cats on their heart and respiratory rates, blood pressure, body temperature, and sedation quality compared to the intramuscular route (IM). The intramuscular group (IMG) received 0.003 mg...

Author(s)
Paolini, A.; Vignoli, M.; Guerri, G.; Falerno, I.; Tamburro, R.; Simeoni, F.; Signore, F. del; Bonis, A. de; Collivignarelli, F.; Salvo, M. C.; Cerasoli, I.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2022, 9, 10,

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