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Abstract

Feline immunodeficiency virus (FIV) is a naturally occurring T-cell tropic lentiviral disease of felids with many similarities to HIV/AIDS in humans. Similar to primate lentiviral-host interactions, feline APOBEC3 (A3) has been shown to inhibit FIV infection in a host-specific manner and feline A3...

Author(s)
Troyer, R. M.; Malmberg, J. L.; Zhe Xin; Miller, C.; MacMil, M.; Sprague, W. S.; Wood, B. A.; Vandew, S.
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2019, 11, 9,
Abstract

Cats are becoming more popular as household companions and pets, forming close relationships with humans. Although feline viral diseases can pose serious health hazards to pet cats, commercialized preventative vaccines are lacking. Interferons (IFNs), especially type I IFNs (IFN-α, IFN-β, and ...

Author(s)
Wang XiaoNa; Li FengSai; Han MeiJing; Jia Shuo; Wang Li; Qiao XinYuan; Jiang YanPing; Cui Wen; Tang LiJie; Li YiJing; Xu YiGang
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2020, 12, 3,
Abstract

This study describes clinical and histopathological features, treatment, and outcome of cats diagnosed with ocular mycobacteriosis. Cases diagnosed from 2012 to 2017 were reviewed for (a) histopathological evidence of ocular (pyo)granulomatous inflammation containing acid-fast bacilli with...

Author(s)
Stavinohova, R.; O'Halloran, C.; Newton, J. R.; Oliver, J. A. C.; Scurrell, E.; Gunn-Moore, D. A.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Veterinary Pathology, 2019, 56, 5, pp 749-760
Abstract

Feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV), two of the most important pathogens of cats, produce chronic systemic diseases with progressive death of cells involved in the immune response, ultimately leading to death. Immunostimulants is one of the few alternatives to the...

Author(s)
Gomez-Lucia, E.; Collado, V. M.; Miró, G.; Martín, S.; Benítez, L.; Doménech, A.
Publisher
MDPI AG, Basel, Switzerland
Citation
Animals, 2020, 10, 9,
Abstract

Specific treatments for the long-life infections by feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) are either toxic, expensive or not too effective. Interferon α (IFN-α) is an immunomodulatory molecule which has been shown in vitro to decrease the release of infective...

Author(s)
Gomez-Lucia, E.; Collado, V. M.; Miró, G.; Martín, S.; Benítez, L.; Doménech, A.
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2019, 11, 9,
Abstract

Interleukin 18 (IL-18) can induce IFN-γ secretion, promote the proliferation and differentiation of T and Blymphocytes, and has good antiviral activity. In this study, in order to explore the biological activity of feline IL-18, a combination ofvesicular stomatitis virus (VSV) and poly I:C was used ...

Author(s)
Li Hua; Han WuJiao; Niu Chao; Pan RongHui; Jiang YanPing; Cui Wen; Li YiJing; Xu YiGang
Publisher
Chinese Journal of Preventive Veterinary Medicine, Harbin, China
Citation
Zhongguo Yufang Shouyi Xuebao / Chinese Journal of Preventive Veterinary Medicine, 2020, 42, 6, pp 612-616
Abstract

This is the first report of a successful treatment of a non-effusive feline infectious peritonitis (FIP) uveitis case using an oral adenosine nucleoside analogue drug and feline interferon omega, and alpha-1 acid glycoprotein (AGP) as an indicator of recovery. A 2-year-old male neutered Norwegian...

Author(s)
Addie, D. D.; Covell-Ritchie, J.; Jarrett, O.; Fosbery, M.
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2020, 12, 11,
Abstract

Objectives: Mycobacterium bovis, a member of the Mycobacterium tuberculosis complex, can infect cats and has proven zoonotic risks for owners. Infected cats typically present with a history of outdoor lifestyle and hunting behaviour, and cutaneous granulomas are most commonly observed. The aim of...

Author(s)
O'Halloran, C.; Ioannidi, O.; Reed, N.; Murtagh, K.; Dettemering, E.; Poucke, S. van; Gale, J.; Vickers, J.; Burr, P.; Gascoyne-Binzi, D.; Howe, R.; Dobromylskyj, M.; Mitchell, J.; Hope, J.; Gunn-Moore, D.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2019, 21, 8, pp 667-681
Abstract

Objectives: Feline infectious peritonitis (FIP) is a high mortality infectious disease. Single nucleotide polymorphisms (SNPs) in the genes encoding interferon gamma (IFNG), tumour necrosis factor alpha (TNFA) and dendritic cell-specific intercellular adhesion molecule-grabbing non-integrin...

Author(s)
Kedward-Dixon, H.; Barker, E. N.; Tasker, S.; Kipar, A.; Helps, C. R.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2020, 22, 6, pp 564-570
Abstract

Feline infectious peritonitis (FIP), caused by virulent feline coronavirus, is the leading infectious cause of death in cats. The type I interferon (type I IFN)-mediated immune responses provide host protection from infectious diseases. Several coronaviruses have been reported to evolve diverse...

Author(s)
Chen Si; Li ZhiJie; Tian Jin; Kang HongTao; Zhang JiKai; Huang JiaPei; Yin Hang; Hu XiaoLiang; Qu LianDong
Publisher
MDPI AG, Basel, Switzerland
Citation
Viruses, 2020, 12, 1,

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