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VetMed Resource

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Abstract

Background: In people, obesity and prediabetes mellitus might predispose to chronic kidney disease (CKD). Aims: To assess the association of overweight [Body condition score (BCS) >5] and glucose metabolism alterations, with established or potential markers of CKD. In addition, fructosamine and...

Author(s)
Pérez-López, L.; Boronat, M.; Melián, C.; Brito-Casillas, Y.; Wägner, A. M.
Publisher
Taylor & Francis, Abingdon, UK
Citation
Veterinary Quarterly, 2020, 40, 132-139, pp 132-139
Abstract

Diabetes mellitus is a common endocrinopathy of cats that is characterized by persistent fasting hyperglycemia. However, stress induces substantial hyperglycemia in cats that poses a challenge to the veterinarian who may wrongly interpret the high serum concentration of blood glucose as evidence of ...

Author(s)
Gal, A.; Trusiano, B.; French, A. F.; Lopez-Villalobos, N.; MacNeill, A. L.
Publisher
MDPI AG, Basel, Switzerland
Citation
Veterinary Sciences, 2017, 4, 1, pp 17
Abstract

Objectives: The objective was to evaluate a nadir-led protocol for transitioning porcine lente insulin suspension (PLIS)-treated diabetic cats onto human recombinant protamine zinc insulin (PZIR). Methods: Recently diagnosed (<5 months) diabetic cats, treated with PLIS q12h for ≥6 weeks, were recruited. Fructosamine,...

Author(s)
Gostelow, R.; Hazuchova, K.; Scudder, C.; Forcada, Y.; Church, D.; Niessen, S. J. M.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2018, 20, 2, pp 114-121
Abstract

Background: Treatment of diabetes mellitus (DM) in cats typically requires insulin injections q12h-q24h, posing a major compliance barrier for caregivers. Novel treatments enabling decreased injection frequency while maintaining safety are highly desirable. Insulin fused with feline immunoglobulin...

Author(s)
Gilor, C.; Hulsebosch, S. E.; Pires, J.; Bannasch, M. J.; Lancaster, T.; Delpero, A.; Ragupathy, R.; Murikipudi, S.; Zion, T.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2021, 35, 5, pp 2123-2130
Abstract

Background: Both diabetes mellitus (DM) and obesity are common in cats. The adipokines leptin, adiponectin, resistin and omentin are thought to have important roles in human obesity and glucose homeostasis; however, their functions in the pathophysiology of feline diabetes mellitus and obesity are...

Author(s)
Williams, M. C.; McMillan, C. J.; Snead, E. R.; Takada, K.; Chelikani, P. K.
Publisher
BioMed Central Ltd, London, UK
Citation
BMC Veterinary Research, 2019, 15, 332, pp (18 September 2019)
Abstract

Objectives: An affordable and effective treatment is needed to manage feline hypersomatotropism. The aim of this study was to assess whether treatment with oral cabergoline for 90 days in cats with hypersomatotropism and diabetes mellitus improved diabetic and insulin-like growth factor 1 (IGF-1)...

Author(s)
Scudder, C. J.; Hazuchova, K.; Gostelow, R.; Church, D. B.; Forcada, Y.; Fowkes, R. C.; Niessen, S. J. M.
Publisher
Sage Publications, Thousand Oaks, USA
Citation
Journal of Feline Medicine and Surgery, 2021, 23, 2, pp 131-137
Abstract

The objective of this study was to compare inhaled glucocorticoids with oral glucocorticoids for treatment of naturally occurring feline asthma. Secondary goals were to evaluate serum allergy testing results in cats and to quantify the effect of an inhaled glucocorticoid (fluticasone) on glucose...

Author(s)
Verschoor-Kirss, M.; Rozanski, E. A.; Sharp, C. R.; Oura, T. J.; Egan, A.; Bain, P.; Knoll, J.
Publisher
Canadian Veterinary Medical Association, Ottawa, Canada
Citation
Canadian Journal of Veterinary Research, 2021, 85, 1, pp 61-67
Abstract

Background: Insulin-like growth factor-I (IGF-I) is used to screen for acromegaly in diabetic cats. In humans, most circulating IGF-I forms ternary complexes (TC) with IGF-binding protein (IGFBP-3) and an acid-labile subunit. Compared to humans, the amount of TC in cats is more variable....

Author(s)
Strage, E. M.; Sundberg, M.; Holst, B. S.; Franko, M. A.; Ramström, M.; Fall, T.; Lewitt, M.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2018, 32, 5, pp 1579-1590
Abstract

Background: Long-term medical management of hypersomatotropism (HS) in cats has proved unrewarding. Pasireotide, a novel somatostatin analogue, decreases serum insulin-like growth factor 1 (IGF-1) and improves insulin sensitivity in cats with HS when administered as a short-acting preparation....

Author(s)
Gostelow, R.; Scudder, C.; Keyte, S.; Forcada, Y.; Fowkes, R. C.; Schmid, H. A.; Church, D. B.; Niessen, S. J. M.
Publisher
Wiley, Boston, USA
Citation
Journal of Veterinary Internal Medicine, 2017, 31, 2, pp 355-364
Abstract

Obesity and inactivity are major risk factors of feline diabetes mellitus (FDM) and human type II diabetes mellitus (T2DM). In recent years, changes in the gut microbiota have been suggested as a contributing factor to T2DM. Whether the gut microbiota (GM) composition plays a role in FDM remains...

Author(s)
Kieler, I. N.; Osto, M.; Hugentobler, L.; Puetz, L.; Gilbert, M. T. P.; Hansen, T.; Pedersen, O.; Reusch, C. E.; Zini, E.; Lutz, T. A.; Bjørnvad, C. R.
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2019, 9, 1, pp 4822

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