The autoagglutination test and direct and indirect Coombs, tests are used in the diagnosis of immune-mediated haemolytic anaemia (IMHA). The autoagglutination test is a test that the veterinary practitioner can easily implement in the clinic, but is only useful if autoagglutination is detected in...

Objectives: Increased erythrocytic osmotic fragility and splenomegaly have been reported in anemic Abyssinian and Somali cats. Here we report on this condition in anemic domestic shorthair cats and two other breeds, and describe common features of the clinicopathological profiles, management and...

Immune-mediated hemolytic anemia (IMHA) occurs less frequently in cats than in dogs. The value of the Coombs' test (CT) has been questioned, but detailed surveys of its use are lacking. The objective of this study was to describe 19 cats with primary IMHA (pIMHA) and to examine the diagnostic value ...

Erosive polyarthritis was diagnosed in an 11-month-old neutered male Egyptian Mau-cross cat with concurrent glucocorticoid-responsive dermatitis. Clinical signs, synovial fluid analysis, serological tests and radiographic appearance could not differentiate between immune-mediated and infective...

Immune-mediated hemolytic anemia (IMHA) is a common type of anemia in dogs and cats that results from a type II hypersensitivity reaction. The disease is most common in middle-aged female dogs, especially American cocker spaniels. The common clinical signs are associated with severe anemia and the...

The preparation of a feline Coombs serum (rabbit anti-feline gamma globulin) is described. The direct antiglobulin test using this serum was performed on 20 anaemic and 20 healthy control cats. Red cell membrane antibodies were detected in cats with feline leukaemia virus infection and in others...

Nine of 105 cats with hyperthyroidism treated with propylthiouracil developed a serious immune-mediated drug reaction. Adverse clinical signs, which developed after 19-37 days (mean 24.8 days) of propylthiouracil administration, included lethargy, weakness, anorexia, and bleeding diathesis....

Diagnostic techniques reviewed are tests to diagnose systemic immune-mediated skin diseases, histopathological evaluation of skin, direct immunofluorescence testing, immunoperoxidase testing, blood tests, haematology and blood chemistry, antinuclear antibody test, lupus erythematosus cell test, ...

A case of cold agglutinin disease in a 5-year-old Abyssinian cat is described. Ten days after upper respiratory tract infection which responded to symptomatic treatment, the animal showed dry gangrene of front paws, ear tips and the distal half of the tail and mild splenomegaly on palpation....

In 15 experimentally infected cats H. felis appeared on erythrocytes 3-18 days) (average 6.7 days) after inoculation. The erythrocyte count and haematocrit and haemoglobin values decreased during the appearance of H. felis on erythrocytes. They tended, however, to return gradually to their previous ...