Twenty-one cats with hypertrophic cardiomyopathy were enrolled in this study to determine if the administration of benazepril (0.5 mg/kg body weight [BW], PO, q24h) to cats with subclinical hypertrophic cardiomyopathy improves cardiac diastolic function and reverses left ventricular hypertrophy...

Serum diltiazem concentrations were evaluated following either 30 mg or 60 mg of an extended-release diltiazem administered orally once daily to 13 cats. Sequential blood samples were obtained over 24 hours. Both dosages usually resulted in elevated serum concentrations of >200 ng/mL at 6, 12, 18,...

A case of a nine-year-old spayed Himalayan female cat, 3.2 kg, is reported due to endocardial hyperechogenicity and accumulation of pleural effusion. The cat was diagnosed with restrictive cardiomyopathy (RCM) and was treated without any improvement in clinical conditions. The cat was introduced to ...

This article discusses tips on the treatment of arrhythmias in pets and presents the latest diagnostic and therapeutic tools available to the clinician.

The pharmacokinetics of diltiazem HCl (DLT) administered i.v. (single dose of 0.1 mg/kg) or orally (1 mg/kg, 3 times a day) and slow-absorption long-acting diltiazem (CD) given orally (10 mg/kg, once daily) were investigated in 6 cats. The effects of DLT and CD on heart rate and PR interval were...

Platelet aggregation in response to collagen (1 or 3 µg/ml), arachidonic acid (10^-2 M), and adenosine diphosphate (ADP, 2 µM) was compared in healthy cats treated with diltiazem (approximately 2 mg/kg body weight, q 8 h for 10 doses), aspirin (approximately 21 mg/kg, q 72 h for 3 doses), or a...

A 2-year-old, female, Turkish Angora cat was presented due to hindlimb paralysis with 2-day history of vomiting and depression. Physical examination revealed weak femoral pulse and cyanotic footpads of hind limbs. Chest auscultation, thoracic radiography, and electrocardiogram were no remarkable....

One of the consequences of blunt trauma in dogs, though extremely rare in cats, can be traumatic myocarditis, a syndrome of arrhythmias, rather than true inflammation of the myocardium. The pathogenesis of this syndrome is still not fully understood, though reperfusion injury, disorders of...

To determine the efficacy of, and clinical response to, several pharmacological agents for treatment of idiopathic hypertrophic cardiomyopathy in cats, 17 symptomatic cats were randomly assigned for treatment with either propranolol, diltiazem, or verapamil. Clinical, laboratory, radiographic,...