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The effects of muscle relaxants on the urethral pressure profiles of cats with obstructive lower urinary tract disease were investigated. Three cats were treated with dantrolene sodium (1 mg/kg body wt., i.v.) alone, and 3 cats were treated with dantrolene sodium in combination with prazosin (0.03...
Effects of the neuromuscular blocking agent succinylcholine (n = 9), the centrally acting skeletal muscle relaxant diazepam (n = 11), and the directing skeletal muscle relaxant dantrolene sodium (n = 8) on the urethral pressure profile were evaluated in anaesthetized, healthy, sexually intact,...
This article discusses urine storage and voiding as well as drug therapies that can be utilized in the event of nervous system problems. Focus is given on the neuroanatomical components and processes involved in the storage and voiding of urine.
Pressure within the urethra was reduced by i.v. injection of suxamethonium at 0.075 mg/kg and by dantrolene sodium at 1 mg/kg, but not by diazepam.
Malignant hyperthermia (MH) is one of a number of inherited muscle disorders that was first reported in humans in 1960. This potentially fatal...