OBJECTIVE: To evaluate IV iron sucrose safety and impact on hematologic and iron indices in healthy cats. ANIMALS: 5 healthy research cats. PROCEDURES: Cats were administered iron sucrose (0.5 mg/kg, IV) over 30 minutes. Monitoring for acute reactions (temperature, heart rate, respiratory rate, and ...

Background: Reticulocyte indices have been suggested as alternatives to transferrin saturation (TSAT) for iron status assessment in humans and dogs but they have not been evaluated thoroughly in cats. Objectives: To assess the value of the reticulocyte indices for the diagnosis of iron deficiency...

Background: Iron deficiency and cobalamin deficiency, as sequelae to chronic gastrointestinal (GI) disease, could result in anemia and increased morbidity in cats with chronic enteropathies. Objective: To evaluate iron deficiency in cats with chronic GI disease and its relationship with...

Background: Chronic iron overload could induce nephropathy via oxidative stress and inflammation, and chelating therapy has limited efficacy in removing excess intracellular iron. Although vitamin D (VD) has shown potent antioxidant and anti-inflammatory effects, as well contribute to iron...

Background: Iron deficiency is a proposed mechanism for the anemia that occurs in cats with chronic kidney disease (CKD). Minimal research investigating the iron status of these cats has been performed. Objective: To compare indicators of iron status in cats with CKD versus healthy cats and cats...

Background: The role of inflammation in the development and progression of chronic kidney disease (CKD) in cats is not well characterized. Hepcidin is a recently discovered acute-phase protein (APP) that plays an important role in iron metabolism and contributes to the development of anemia in...

Background: Decreased reticulocyte hemoglobin content (CHr) (Siemens ADVIA 2120) reflects iron-limited erythropoiesis (ILE). RETIC-HGB (IDEXX ProCyte Dx) is a novel marker of ILE for veterinary use. Objectives: We aimed to evaluate reference intervals (RIs) and the utility of RETIC-HGB and CHr in...

Objectives: To measure iron parameters and markers of inflammation in anaemic cats presented for intensive care unit hospitalisation, and to compare these to cohorts of non-anaemic hospitalised cats and cats that develop hospital-acquired anaemia. Methods: Blood samples were collected for...

This study was aimed to evaluate the effects of dietary iron on growth, haematology oxidative stress and determine the optimum dietary iron level for Heteropneustes fossilis by feeding graded levels of iron (6.9, 25.5, 47.0, 66.7, 86.6, 107.1, 126.8 and 146.9 mg kg^-1) achieved by supplementing...

This experiment aimed to study the effects of compound organic trace minerals (iron, copper, manganese, zinc and selenium) reducing level instead of inorganic trace minerals on growth performance, meat quality, serum antioxidant capacity and fecal trace element emissions of meat ducks. A total of...