Background: Activity of the circulating renin-angiotensin-aldosterone system (RAAS) has not been comprehensively characterized in cats with systemic hypertension (SH) or cardiomyopathy (CM), and the effects of furosemide or amlodipine treatment on the RAAS have not been fully evaluated in cats....

Background: Hypertension is a common problem in elderly cats. In most cats, systolic blood pressure (SBP) of <160 mmHg is achieved in response to amlodipine besylate at either 0.625 or 1.25 mg q24h. The individual cat factors determining dose requirement dose have not been explored. Aims: To determine whether individual cat factors...

Background: There is an unmet clinical need for a cat-specific formulation of amlodipine to treat hypertensive cats. Objectives: To assess the efficacy of chewable amlodipine tablets in reducing systolic blood pressure (SBP) in cats diagnosed with systemic arterial hypertension. Animals:...

Objectives: To determine the prevalence of ocular fundus abnormalities in cats with a diagnosis of systemic hypertension, to characterize the abnormalities observed, and to evaluate ophthalmoscopic evolution during treatment with amlodipine besylate. Animals studied: Cats diagnosed as affected by...

Secondary hypertension caused by an underlying disease is common in older cats, especially in those with chronic kidney disease and/or hyperthyroidism. Systolic blood pressure should be measured whenever an associated disease is diagnosed and persistent systolic blood pressure >160 mmHg should...

Objectives: Hypertensive emergency is well recognised in human medicine, yet there is limited veterinary evidence. This study aimed to determine the presentation, treatment and outcome in dogs and cats with hypertensive emergency. Materials and Methods: A retrospective case series of dogs and cats...

A 14-year-old male neutered European Shorthair was referred for hypokalemic polymyopathy manifesting as weakness and cervical ventroflexion. Further examinations revealed concurrent systemic hypertension and sonographically bilateral adrenal gland enlargement. The blood aldosterone concentration...

Case summary: Systemic arterial hypertension is commonly reported in middle-aged-to-older cats. Amlodipine is recommended as the initial antihypertensive drug in cats. In this case report, gingival hyperplasia secondary to the use of amlodipine in a cat is described. Benazepril as a monotherapy was ...

Objective: To describe and document the prevalence and cause of iris aneurysm in feline hypertensive oculopathy. Animals studied Privately owned cats with systemic hypertension presented for sudden visual deficits and/or hyphema. Procedures: A retrospective search of medical records of cats with...

Systolic arterial hypertension is often recognized in the clinical practice of feline internal medicine and is a common problem in older cats. This disease is usually secondary to other diseases, such as chronic kidney disease and hyperthyroidism. However, in some patients the underlying cause is...