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Abstract

This study examined the effect of minocycline alone and in combination with immunotherapy against pythiosis. Twenty rabbits, aged three months old and subcutaneously inoculated with Pythium insidiosum zoospores were divided into four groups (n = 5): treated with minocycline (10 mg/kg/day twice...

Author(s)
Zimmermann, C. E. P.; Jesus, F. P. K.; Schlemmer, K. B.; Loreto, É. S.; Tondolo, J. S. M.; Driemeier, D.; Alves, S. H.; Ferreiro, L.; Santurio, J. M.
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2020, 243,
Abstract

Background: Chronic hepatitis B and D virus (HBV/HDV) infections can cause cancer. Current HBV therapy using nucleoside analogues (NAs) is life-long and reduces but does not eliminate the risk of cancer. A hallmark of chronic hepatitis B is a dysfunctional HBV-specific T-cell response. We therefore ...

Author(s)
Maravelia, P.; Frelin, L.; Ni Yi; Pérez, N. C.; Ahlén, G.; Jagya, N.; Verch, G.; Verhoye, L.; Pater, L.; Johansson, M.; Pasetto, A.; Meuleman, P.; Urban, S.; Sällberg, M.
Publisher
Oxford University Press, Oxford, UK
Citation
Journal of Infectious Diseases, 2020, 223, 1, pp 128-138
Abstract

Myxoma virus (MYXV) is the prototypic member of the Leporipoxvirus genus of the Poxviridae family of viruses. In nature, MYXV is highly restricted to leporids and causes a lethal disease called myxomatosis only in European rabbits (Oryctologous cuniculus). However, MYXV has been shown to also...

Author(s)
Rahman, M. M.; McFadden, G.
Publisher
MDPI AG, Basel, Switzerland
Citation
Vaccines, 2020, 8, 2,
Abstract

Pseudomonas aeruginosa is among the most formidable antibiotic-resistant pathogens and is a leading cause of hospital-associated infections. With dwindling options for antibiotic-resistant infections, a new paradigm for treatment and disease resolution is required. MEDI3902, a bispecific antibody...

Author(s)
Le, H. N.; Quetz, J. S.; Tran, V. G.; Le, V. T. M.; Aguiar-Alves, F.; Pinheiro, M. G.; Cheng, L.; Yu Li; Sellman, B. R.; Stover, C. K.; Digiandomenico, A.; Binh An Diep
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Antimicrobial Agents and Chemotherapy, 2018, 62, 5, pp e02565
Abstract

Introduction: Allergic Rhinitis (AR) effects 20-40% of the global population and its prevalance increases. Medical treatment and immunotherapy could be used in AR management. But they are not definitive solution. Medical treatment must be used a long time and has side effects. Immunotherapy cannot...

Author(s)
Güneș, M. S.; Külahlı, I.; Kökoğlu, K.; Vural, A.; Avcı, D.; Güleç, S.; Sönmez, M. F.; Çilenk, K. T.; Erçal, B. D.
Publisher
Elsevier Science Ireland Ltd., Shannon, Irish Republic
Citation
International Journal of Pediatric Otorhinolaryngology, 2016, 83, pp 51-56
Abstract

Envenoming by scorpion is a major health problem in Maghreb regions as well as in several regions of the world. Immunotherapy is the only effective treatment for scorpion stings. The immune sera are obtained from hyper-immunized animals with a formulation of venom associated to Freund's Complete...

Author(s)
Nouri, A.; Mohamed, F. A. N.; Laraba-Djebari, F.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2018, 36, 13, pp 1720-1727
Abstract

Active and passive immunotherapy targeting amyloid-β (Aβ) may be the most promising strategy to prevent or treat Alzheimer's disease (AD). Previously, immunization with the recombinant 6Aβ15-T antigen generated robust anti-Aβ serum antibodies that strongly recognized Aβ42 oligomers in different...

Author(s)
Wang HaiChao; Yu YunZhou; Liu Si; Zhao Meng; Xu Qing
Publisher
Elsevier Ltd, Oxford, UK
Citation
Vaccine, 2016, 34, 15, pp 1758-1766
Abstract

Treatment of scorpion envenomation is a challenging issue since serotherapy is implemented by administration of polyvalent equine antisera. In our previous study we discovered that recombinant phospholipase D1 (Hl-RecPLD1) is responsible for the lethality of Hemiscorpius lepturus (H. lepturus)...

Author(s)
Torabi, E.; Behdani, M.; Khalaj, V.; Pooshang, K. B.; Shahbazzadeh, D.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Toxicon, 2020, 183, pp 36-43
Abstract

This study investigated the in vivo antimicrobial activity of the essential oils of Origanum vulgare and Mentha piperita both singly, associated and in combination with immunotherapy to treat experimental pythiosis. The disease was reproduced in 18 rabbits divided into six groups (n=3): group 1,...

Author(s)
Fonseca, A. O. S.; Pereira, D. I. B.; Botton, S. A.; Pötter, L.; Sallis, E. S. V.; Júnior, S. F. V.; Filho, F. S. M.; Zambrano, C. G.; Maroneze, B. P.; Valente, J. S. S.; Baptista, C. T.; Braga, C. Q.; Ben, V. dal; Meireles, M. C. A.
Publisher
Elsevier B. V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2015, 178, 3/4, pp 265-269
Abstract

The use of nucleic acid as a drug substance for vaccines and other gene-based medicines continues to evolve. Here, we have used a technology originally developed for mRNA in vivo delivery to enhance the immunogenicity of DNA vaccines. We demonstrate that neutralizing antibodies produced in rabbits...

Author(s)
Mucker, E. M.; Karmali, P. P.; Vega, J.; Kwilas, S. A.; Wu Hua; Joselyn, M.; Ballantyne, J.; Sampey, D.; Rajesh Mukthavaram; Sullivan, E.; Chivukula, P.; Hooper, J. W.
Publisher
Nature Publishing Group, London, UK
Citation
Scientific Reports, 2020, 10, 5,

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