Ventilator-associated pneumonia is an important clinical manifestation of the nosocomial pathogen Pseudomonas aeruginosa. We characterized the correlates of protection with MEDI3902, a bispecific human IgG1 monoclonal antibody that targets the P. aeruginosa type 3 secretion system PcrV protein and...
Author(s)
Aguiar-Alves, F.; Le, H. N.; Tran, V. G.; Gras, E.; Vu, T. T. T.; Dong, O. X.; Quetz, J. S.; Cheng, L. I.; Yu Li; Sellman, B. R.; Stover, C. K.; Digiandomenico, A.; Diepa, B. A.
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Antimicrobial Agents and Chemotherapy, 2022, 66, 2,
Bordetella bronchiseptica and Klebsiella pneumoniae infections are extremely harmful to the breeding of rabbits. They often cause multiple respiratory diseases. To determine the pathogens that cause dyspnea and diarrhea in rabbits, suspected dead rabbits in the rabbit farm were subjected to...
Author(s)
Zhang ZiQiang; Wang JiaJia; Ren YuYing; Zhu HuiJie; Zhang QianWen; Liu YuMei
Publisher
Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China
Citation
Acta Veterinaria et Zootechnica Sinica, 2021, 52, 8, pp 2254-2264
Development and validation of large animal models of Pseudomonas aeruginosa ventilator-associated pneumonia are needed for testing new drug candidates in a manner that mimics how they will be used clinically. We developed a new model in which rabbits were ventilated with low tidal volume and...
Author(s)
Nguyen, N. T. Q.; Gras, E.; Tran, N. D.; Nguyen, N. N. Y.; Lam, H. T. H.; Weiss, W. J.; Doan, T. N. M.; Diep, B. A.
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Antimicrobial Agents and Chemotherapy, 2021, 65, 7,
Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae (KPC-Kp) is an emerging global public health threat that causes life-threatening pneumonia and bacteremia. Ceftazidime-avibactam (CZA) represents a promising advance for the treatment of serious infections caused by KPC-Kp. We...
Author(s)
Petraitiene, R.; Petraitis, V.; Kavaliauskas, P.; Maung, B. B. W.; Khan, F.; Naing, E.; Aung, T.; Zigmantaite, V.; Grigaleviciute, R.; Kucinskas, A.; Stakauskas, R.; Georgiades, B. N.; Mazur, C. A.; Hayden, J. A.; Satlin, M. J.; Walsh, T. J.
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Antimicrobial Agents and Chemotherapy, 2020, 64, 4,
Stenotrophomonas maltophilia is an important cause of pneumonia in immunocompromised patients. Cefiderocol is a parenteral siderophore cephalosporin with potent in vitro activity against S. maltophilia. We evaluated the efficacy of cefiderocol in a neutropenic rabbit model of S. maltophilia ...
Author(s)
Petraitis, V.; Petraitiene, R.; Kavaliauskas, P.; Naing, E.; Garcia, A.; Georgiades, B. N.; Echols, R.; Bonomo, R. A.; Yamano, Y.; Satlin, M. J.; Walsh, T. J.
Publisher
American Society for Microbiology (ASM), Washington, D.C., USA
Citation
Antimicrobial Agents and Chemotherapy, 2022, 66, 10,
Staphylococcus aureus is one of the most important pathogens causing rabbit necrotizing pneumonia and brings huge economic losses to rabbit production. This study investigated the preventive effect of a phage on rabbit necrotizing pneumonia caused by S. aureus. S. aureus S6 was isolated from the...
Author(s)
Ji YaLu; Cheng MengJun; Zhai ShengJie; Xi HengYu; Cai RuoPeng; Wang ZiJing; Zhang Hao; Wang XinWu; Xue YiBing; Li XinWei; Sun ChangJiang; Feng Xin; Lei LianCheng; Sadeeq-ur-Rahman; Han WenYu; Gu JingMin
Publisher
Elsevier B.V., Amsterdam, Netherlands
Citation
Veterinary Microbiology, 2019, 229, pp 72-80
Staphylococcus aureus is a well-known pathogen that infects humans and animals. However, information on the fatal respiratory infection in rabbits caused by S. aureus is still limited. In the present study, a S. aureus isolate designated ND01 was recovered from lung samples of rabbits that died of...
Author(s)
Wang JinXiang; Sun, S.; Chen, Y.; Chen, D.; Sang, L.; Xie, X.
Publisher
Universidad Politécnica de Valencia, Valencia, Spain
Citation
World Rabbit Science, 2021, 29, 2, pp 99-107
To investigate the pathogenic bacteria of rabbit respiratory system infection and their resistance to antibiotics in Henan province, the pathogenic bacteria were isolated and identified from 143 rabbit samples with respiratory system infection collected from 36 large-scale rabbit farms in Henan...
Author(s)
Zhang ZiQiang; Wang JiaJia; Xie Hui; Zhang Xin; Xu JingYi; Chang ZhaoYang; Liu Ning; Liu YuMei
Publisher
Chinese Journal of Preventive Veterinary Medicine, Harbin, China
Citation
Zhongguo Yufang Shouyi Xuebao / Chinese Journal of Preventive Veterinary Medicine, 2022, 44, 7, pp 718-724
Background: The pre and post-weaning mortality in broiler rabbit limits the production potential and lower the income generation through rabbit farming. Therefore, mortality pattern of animals in a farm is very essential clue for future strategy to combat the incidences of various diseases and...
Author(s)
Asit Chakrabarti
Publisher
Agricultural Research Communication Centre, Karnal, India
Citation
Indian Journal of Animal Research, 2021, 55, 1, pp 115-119
Mannheimia haemolytica is the causal agent of the shipping fever in bovines and produces high economic losses worldwide. This bacterium possesses different virulence attributes to achieve a successful infection. One of the main virulence factors expressed by a pathogen is through adhesion...
Author(s)
Figueroa-Valenzuela, C.; Montes-García, J. F.; Vazquez-Cruz, C.; Zenteno, E.; Pereyra, M. A.; Negrete-Abascal, E.
Publisher
Elsevier Ltd, Oxford, UK
Citation
Microbial Pathogenesis, 2022, 172,